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Triethyl citrate

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Identification
Molecular formula
C12H20O7
CAS number
77-93-0
IUPAC name
triethyl 2-hydroxypropane-1,2,3-tricarboxylate
State
State

At room temperature, triethyl citrate is a liquid. This state is consistent even with slight variations in temperature, given its melting point well below room temperature.

Melting point (Celsius)
-55.00
Melting point (Kelvin)
218.15
Boiling point (Celsius)
294.00
Boiling point (Kelvin)
567.15
General information
Molecular weight
276.29g/mol
Molar mass
276.2630g/mol
Density
1.1370g/cm3
Appearence

Triethyl citrate is a colorless or pale yellow liquid. It is an odorless compound that is typically used as a plasticizer or as a solvent. The liquid nature and lack of color make it versatile for various industrial and pharmaceutical applications.

Comment on solubility

Solubility of Triethyl 2-hydroxypropane-1,2,3-tricarboxylate

Triethyl 2-hydroxypropane-1,2,3-tricarboxylate, a triester of citric acid, exhibits unique solubility characteristics that can be influenced by various factors. Understanding its solubility is crucial for applications in fields like pharmaceuticals, food science, and chemical engineering.

Key Points on Solubility:

  • Polar Nature: Due to the presence of three carboxylate groups, this compound tends to be polar, which generally favors solubility in polar solvents.
  • Solvent Compatibility: It is highly soluble in water and other polar solvents. This makes it suitable for aqueous formulations.
  • Temperature Factor: Like many organic compounds, its solubility may increase with temperature, allowing for better integration in solutions during processes such as dissolution.
  • pH Influence: The solubility of this compound can be affected by the pH of the solution, as the ionization state of the carboxyl groups will alter in acidic or basic environments.

In practical terms, when preparing solutions containing triethyl 2-hydroxypropane-1,2,3-tricarboxylate, one might consider:

  • The solvent choice (preferably water or polar organic solvents)
  • The temperature during preparation
  • The pH level of the solution being used

Ultimately, understanding these solubility aspects will enable Chemists to exploit the properties of triethyl 2-hydroxypropane-1,2,3-tricarboxylate effectively in various applications!

Interesting facts

Interesting Facts About Triethyl 2-Hydroxypropane-1,2,3-tricarboxylate

Triethyl 2-hydroxypropane-1,2,3-tricarboxylate, often abbreviated to THT, is an intriguing compound with various applications in the chemical industry. Here are some interesting facts that highlight its significance:

  • Prolific Use in Chemistry: THT is utilized as a key reagent in organic synthesis, making it an essential tool for chemists aiming to synthesize complex molecules.
  • Efficient Plasticizer: This compound acts as an effective plasticizer, improving the flexibility and durability of materials, especially in polymers.
  • Biocompatibility: Due to its structure, THT demonstrates a degree of biocompatibility, making it a candidate for applications in pharmaceutical formulations and medical devices.
  • Environmental Impact: Being a derivative of natural compounds, THT can be seen as a more sustainable option in various applications, aligning with the push towards greener chemistry.
  • Chemical Versatility: The presence of multiple functional groups allows for a variety of chemical reactions, giving researchers a versatile tool for modifying other compounds.

Applications and Research

Ongoing research into THT focuses on:

  • Polymer Science: Exploring new ways to integrate THT into advanced materials.
  • Drug Delivery: Investigating its potential to carry drugs more effectively within the body.
  • Green Chemistry: Developing more environmentally friendly reagents and processes using THT as a starting material.

In summary, triethyl 2-hydroxypropane-1,2,3-tricarboxylate is far more than just a compound; it represents the intersection of innovation and sustainability in modern chemistry. As scientists continue to explore its myriad possibilities, THT stands out as a compound worth watching in the future of chemical research.

Synonyms
TRIETHYL CITRATE
77-93-0
Ethyl citrate
Citroflex 2
Eudraflex
Hydragen CAT
Citric acid, triethyl ester
Triaethylcitrat
Triethylcitrate
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, triethyl ester
Citric Acid Triethyl Ester
triethyl 2-hydroxypropane-1,2,3-tricarboxylate
FEMA No. 3083
Citroflex ec
Citrofol ai
Morflex tec
Crodamol TC
Triaethylcitrat [German]
Uniflex TEC
Citroflex c 2
Triethylester kyseliny citronove
Citroflex sc 60
Morflex c 2
Uniplex 80
Hydagen C.A.T
NSC 8907
HSDB 729
Triethyl citrate (NF)
Triethyl citrate [NF]
Citric acid ethyl ester
UNII-8Z96QXD6UM
NSC-8907
EINECS 201-070-7
8Z96QXD6UM
Triethyl 2-hydroxy-1,2,3-propanetricarboxylate
BRN 1801199
Triethylester kyseliny citronove [Czech]
DTXSID0040701
INS NO.1505
AI3-00659
E1505
INS-1505
2-Hydroxy-1,2,3-propanetricarboxylic acid, triethyl ester
TRIETHYL CITRATE [II]
TRIETHYL CITRATE [FCC]
TRIETHYL CITRATE [FHFI]
TRIETHYL CITRATE [HSDB]
DTXCID8020701
FEMA 3083
TRIETHYL CITRATE [MART.]
NSC8907
E-1505
EC 201-070-7
TRIETHYL CITRATE [USP-RS]
CITRIC ACID ETHYL ESTER [MI]
1,2,3-triethyl 2-hydroxypropane-1,2,3-tricarboxylate
TRIETHYL CITRATE [EP MONOGRAPH]
Ethyl citrate, citric acid triethyl ester
2-Hydroxy-1,2,3-propanetricarboxylic acid, delta triethyl ester
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, 1,2,3-triethyl ester
TEC
TRIETHYL CITRATE (II)
TRIETHYL CITRATE (MART.)
TRIETHYL CITRATE (USP-RS)
TRIETHYL CITRATE (EP MONOGRAPH)
201-070-7
C12H20O7
Triethyl citrate; Triethyl 2-hydroxypropane-1,2,3-tricarboxylate
Triethyl citric acid
Triethyl Citrate, FCC
Triethyl citrate (Standard)
SCHEMBL23465
CHEMBL464988
TRIETHYL CITRATE [INCI]
WLN: 2OV1XQVO2&1VO2
CHEBI:168426
HY-W011602R
Tox21_300004
MFCD00009201
MSK014232
s6223
Triethyl citrate, analytical standard
Triethyl citrate, >=98.0% (GC)
AKOS015838720
CS-W012318
FT33634
HY-W011602
Triethyl citrate, >=99%, FCC, FG
CAS-77-93-0
NCGC00164037-01
NCGC00164037-02
NCGC00253989-01
Triethyl citrate, natural, >=97%, FG
Triethyl citrate, natural, >=99%, FG
BS-18150
1ST014232
DB-056271
MSK014232-1000
Triethyl 2hydroxy1,2,3propanetricarboxylate
NS00008140
triethyl2-hydroxypropane-1,2,3-tricarboxylate
D06228
D70438
Triethyl 2-hydroxy-1,2,3-propane-tricarboxylate
Triethyl citrate, Vetec(TM) reagent grade, 98%
1ST014232-1000
A839294
Q418057
SR-01000883952
Triethyl 2-hydroxy-1,2,3-propanetricarboxylate #
Triethyl citrate Solution in Acetone, 1000?g/mL
Triethyl citrate Solution in Acetone, 1000mug/mL
SR-01000883952-1
2-hydroxy-propane-1,2,3-tricarboxylic acidtriethyl ester
2Hydroxy1,2,3propanetricarboxylic acid, triethyl ester
Flavor and Extract Manufacturers' Association No. 3083
1,2,3-Propanetricarboxylic acid, 2-hydroxy-,triethyl ester
1,2,3Propanetricarboxylic acid, 2hydroxy, triethyl ester
1,3-Propanetricarboxylic acid, 2-hydroxy-, triethyl ester
Triethyl citrate, United States Pharmacopeia (USP) Reference Standard
Triethyl citrate, Pharmaceutical Secondary Standard; Certified Reference Material
629-703-6