Skip to main content

Thiophene-2-carbaldehyde

ADVERTISEMENT
Identification
Molecular formula
C5H4OS
CAS number
98-03-3
IUPAC name
thiophene-2-carbaldehyde
State
State

At room temperature, thiophene-2-carbaldehyde exists as a liquid. It has a relatively low boiling point and should be handled in a well-ventilated area to minimize inhalation exposure. The compound can be volatile, so it's important to ensure proper sealing during storage.

Melting point (Celsius)
-46.00
Melting point (Kelvin)
227.15
Boiling point (Celsius)
87.00
Boiling point (Kelvin)
360.15
General information
Molecular weight
112.16g/mol
Molar mass
112.1550g/mol
Density
1.2040g/cm3
Appearence

Thiophene-2-carbaldehyde is a colorless to pale yellow liquid with a distinctive, pungent odor. Its appearance can vary slightly depending on purity and storage conditions. As a liquid, it is often stored in well-sealed containers to prevent evaporation and maintain its integrity.

Comment on solubility

Solubility of Thiophene-2-carbaldehyde

Thiophene-2-carbaldehyde, a heterocyclic aromatic compound, exhibits intriguing solubility characteristics largely influenced by its molecular structure. When discussing solubility, it is important to note that:

  • Polarity: The presence of the aldehyde functional group increases the polarity of thiophene-2-carbaldehyde, thus enhancing its solubility in polar solvents.
  • Solvent Interaction: Thiophene-2-carbaldehyde is particularly soluble in solvents such as water, ethanol, and acetone.
  • Organic Compatibility: It is also compatible with various organic solvents, making it versatile for different applications.

In terms of its behavior in water, thiophene-2-carbaldehyde exhibits a moderate solubility due to the ability of the aldehyde group to engage in hydrogen bonding with water molecules. This allows it to dissolve more readily compared to less polar thiophene derivatives. As summed up effectively, "The solubility of organic compounds is often a game of polarity and functional groups."

To summarize, while thiophene-2-carbaldehyde shows favorable solubility in both polar and non-polar environments, its practical applications may vary based on the particular solvent used, exemplifying the complex interplay between solubility and chemical structure.

Interesting facts

Interesting Facts about Thiophene-2-carbaldehyde

Thiophene-2-carbaldehyde is an intriguing organosulfur compound belonging to the thiophene family, which is characterized by its five-membered ring structure containing sulfur. Here are some captivating insights that highlight the significance of this compound in both industrial and academic contexts:

  • Versatile Intermediary: Thiophene-2-carbaldehyde acts as an important *intermediate* in the synthesis of various chemical compounds, making it a valuable building block in organic chemistry.
  • Biological Relevance: This compound has been studied for its potential *antibacterial* and *antifungal* properties, opening avenues for developing new pharmaceuticals.
  • Material Science Applications: The unique structure of thiophene derivatives, including thiophene-2-carbaldehyde, enables their use in *conductive polymers* and materials, thereby contributing to advancements in electronics.
  • Synthesis Pathways: Various synthesis methods exist for producing thiophene-2-carbaldehyde, including the *Vilsmeier formylation* of 2-thiophenecarboxylic acid. Understanding these pathways is crucial for chemists aiming to optimize production.
  • Reagent in Reactions: As a reactive aldehyde, thiophene-2-carbaldehyde participates in *condensation reactions* and other transformations that can lead to the formation of more complex organic structures.

In conclusion, thiophene-2-carbaldehyde is more than just an organosulfur compound; it is a versatile chemical with numerous applications across various fields. Chemists continue to explore its properties and reactions, driving innovation in materials science and pharmaceutical development. As it is often described, "the ring structure is not just a feature; it’s a gateway to endless possibilities."

Synonyms
Thiophene-2-carbaldehyde
2-Thiophenecarboxaldehyde
98-03-3
2-Thenaldehyde
Thiophene-2-aldehyde
Thiophene-2-carboxaldehyde
2-Thiophenealdehyde
2-Thienylaldehyde
2-FORMYLTHIOPHENE
2-Thienaldehyde
2-Thienylcarboxaldehyde
2-Thiophene carboxaldehyde
2-Thiophenecarbaldehyde
alpha-Formylthiophene
2-Thiophenaldehyde
formylthiophene
Thenaldehyde
.alpha.-Formylthiophene
alpha-Thiophenecarboxaldehyde
NSC 2162
.alpha.-Thiophenecarboxaldehyde
2-thiophencarboxaldehyde
2-thienal
EINECS 202-629-8
MFCD00005429
THIOFURFURAL
thiophenecarboxaldehyde
AI3-16611
thiophen-2-carbaldehyde
2-FORMYLTHIOFURAN
thiophene-o-carboxaldehyde
2-Carboxaldehyde-thiophene
IW05BB9XBM
2-thiophene carboxyaldehyde
2-THIENYLCARBALDEHYDE
CHEMBL328441
.ALPHA.-THIOPHENALDEHYDE
2-THIOFURANCARBOXALDEHYDE
DTXSID7052656
CHEBI:87301
EC 202-629-8
THIOPHENEALDEHYDE [USP IMPURITY]
PYRANTEL EMBONATE IMPURITY C [EP IMPURITY]
THIOPHENEALDEHYDE (USP IMPURITY)
2-thiophene carbaldehyde
PYRANTEL EMBONATE IMPURITY C (EP IMPURITY)
Thiophene-2-carbaldehyde; Pyrantel Embonate Imp. C (EP)
thiophenaldehyde
2Thienaldehyde
a-Thenaldehyde
thiophenealdehyde
2Formylthiophene
2Thienylaldehyde
2Thiophenealdehyde
thien-2-aldehyde
alphaFormylthiophene
2-formyl-thiophene
thiophen-2-aldehyde
2-thiophene aldehyde
2-thiophene-aldehyde
thien-2-carbaldehyde
2Thienylcarboxaldehyde
Thiophene2carbaldehyde
2-thiophencarbaldehyde
2-Thiophenic aldehyde
alpha -formylthiophene
thiophene carboxaldehyde
thiophen 2-carbaldehyde
thiophen-2 carbaldehyde
Thiophenecarbox-aldehyde
thiophene 2-carbaldehyde
Pyrantel impurity C CRS
thiophen-2-carboxaldehyde
2-thiophene-carboxaldehyde
thiopbene-2-carboxaldehyde
alphaThiophenecarboxaldehyde
WLN: T5SJ BVH
ALPHA-THIOPHENALDEHYDE
SCHEMBL31206
alpha -thiophenecarboxaldehyde
BIDD:GT0227
2-Thiophenecarboxaldehyde, 98%
DTXCID4031229
NSC2162
HY-W012941R
NSC-2162
2-Thiophenecarboxaldehyde (Standard)
AC8106
BDBM50071926
STL194296
AKOS000119051
AC-4923
CS-W013657
FT34619
HY-W012941
PS-9245
BP-10496
SY001071
DB-057703
NS00005456
T0725
EN300-18990
2-Thiophenecarboxaldehyde, (stabilized with HQ)
Q27159509
F2190-0580
Z104472120
202-629-8