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2-Aminothiazole

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Identification
Molecular formula
C3H4N2S
CAS number
96-50-4
IUPAC name
thiazol-2-amine
State
State
At room temperature, 2-aminothiazole is typically found as a solid.
Melting point (Celsius)
88.00
Melting point (Kelvin)
361.15
Boiling point (Celsius)
246.00
Boiling point (Kelvin)
519.15
General information
Molecular weight
100.15g/mol
Molar mass
100.1510g/mol
Density
1.2296g/cm3
Appearence
2-Aminothiazole appears as a pale yellow to yellow crystalline solid. It may also appear in the form of needles or powder.
Comment on solubility

Solubility of Thiazol-2-amine

Thiazol-2-amine, with the chemical formula C3H4N2S, exhibits notable solubility characteristics that can be summarized as follows:

  • Solvent Polarities: Thiazol-2-amine is generally more soluble in polar solvents such as water than in non-polar solvents. This is due to the presence of electronegative atoms (nitrogen and sulfur) that can interact favorably with polar solvents.
  • pH Dependence: The solubility of thiazol-2-amine may vary with pH, as the amine group can become protonated in acidic conditions, potentially increasing its solubility in aqueous solutions.
  • Temperature Effects: Increased temperature typically enhances the solubility of organic compounds in solvents, which is relevant for thiazol-2-amine, making it more soluble at elevated temperatures.
  • Hydrogen Bonding: The ability of thiazol-2-amine to engage in hydrogen bonding with solvents contributes positively to its solubility, especially in aqueous solutions.

Overall, the solubility of thiazol-2-amine makes it a versatile compound in chemical reactions and applications. However, it is essential to consider the specific conditions of the environment when predicting its behavior in a solution.

Interesting facts

Interesting Facts about Thiazol-2-amine

Thiazol-2-amine is a fascinating compound in the realm of organic chemistry, primarily due to its unique structure and versatile applications. Here are some intriguing aspects that you might find captivating:

  • Structural Features: Thiazol-2-amine contains a thiazole ring, a five-membered heterocyclic compound characterized by the presence of both nitrogen and sulfur atoms. This configuration contributes to the chemical's reactivity and properties.
  • Biomedical Significance: Compounds derived from thiazol-2-amine often exhibit notable pharmacological activity. They are investigated for their potential applications in treating various diseases, particularly in the fields of antimicrobial and anti-inflammatory therapies.
  • Synthetic Versatility: Thiazol-2-amine can serve as a building block in organic synthesis, leading to the decoration of more complex molecules. Its ability to participate in various chemical reactions makes it valuable in drug discovery and development.
  • Role in Agrochemicals: This compound is also being explored for its use in agricultural chemicals. Thiazole derivatives can act as fungicides or herbicides, contributing to improved crop protection and yield.

Application Highlights

The versatility of thiazol-2-amine extends to various domains:

  • Pharmaceuticals: It plays a role in designing new therapeutic agents.
  • Agricultural Science: Its derivatives contribute to pest management solutions.
  • Research: Investigations into its properties help expand our understanding of heterocyclic chemistry.

In summary, thiazol-2-amine is not just a simple amine; it embodies the intersection of structure, reactivity, and application in chemical sciences. As research progresses, its potential continues to unfold, paving the way for future innovations!

Synonyms
2-AMINOTHIAZOLE
aminothiazole
96-50-4
thiazol-2-amine
2-Thiazolamine
1,3-Thiazol-2-amine
Abadole
2-Thiazolylamine
Basedol
Abadol
2-Thiazylamine
Aminothiazol
Aminotiazol
4-Thiazolin-2-onimine
2-Amino-1,3-thiazole
Thiazole, 2-amino-
Aminothiazolum
Thiazolamine
Aminothiazole [INN]
2-Aminothiazol
RP 2921
USAF EK-P-5501
Aminotiazolo
Aminotiazolo [DCIT]
2-amino thiazole
Thiazol-2-ylamine
Aminothiazol [INN-French]
Aminotiazol [INN-Spanish]
Aminothiazolum [INN-Latin]
NSC 1900
CCRIS 1279
NSC-1900
EINECS 202-511-6
MFCD00005325
CP 1585
5K8WKN668K
Aminothiazole (INN)
DTXSID5024508
AI3-14917
THIAZOLE,2-AMINO
RP-2921
2-AMINOTHIAZOLE [MI]
CHEMBL344760
DTXCID604508
361381-86-4
CHEBI:40782
NSC1900
29385-37-3
NCGC00091162-02
Aminothiazol (INN-French)
Aminotiazol (INN-Spanish)
Aminothiazolum (INN-Latin)
CAS-96-50-4
AMINOTHIAZOLINE
UNII-5K8WKN668K
amino thiazol
thiazole amine
thiazolyl amine
2-iminothiazole
2-amino thiozol
2-Amino-thiazol
2-amino-thiazole
thiazole-2-amine
N-(2-Methylbenzoyl)glycine-d2; NSC 163983-d2; o-Methylhippuric Acid-d2; o-Toluric Acid-d2;
thiazol-2-yl-amine
amino-1,3-thiazole
2-AMINOTHIOZOLE
Spectrum_000085
1,3-thiazole-2-amine
2-amino-1,3 thiazole
2-Aminothiazole, 97%
1,3-thiazol-2-ylamine
Spectrum2_000879
Spectrum3_001737
Spectrum4_000734
Spectrum5_000973
WLN: T5N CSJ BZ
SCHEMBL7401
1,3-Thiazol-2-amine #
T157602
BSPBio_003414
KBioGR_001028
KBioSS_000505
DivK1c_000176
SPECTRUM1503017
SPBio_000957
HMS500I18
KBio1_000176
KBio2_000505
KBio2_003073
KBio2_005641
KBio3_002634
NINDS_000176
HMS1922A05
HMS3652B11
Pharmakon1600-01503017
STR00409
Tox21_111093
Tox21_200726
2-imino-2,3-dihydro-1,3-thiazole
AC7847
BDBM50240843
CCG-40298
NSC758210
s4198
STK387115
AKOS000119189
CS-3404
FA06181
NSC-758210
PS-9323
IDI1_000176
NCGC00091162-01
NCGC00091162-03
NCGC00091162-04
NCGC00091162-05
NCGC00091162-06
NCGC00091162-07
NCGC00091162-09
NCGC00258280-01
BP-21217
HY-12396
SY001447
2-Aminothiazol, technical, >=90% (NT)
SBI-0051751.P002
DB-015940
A0633
NS00020245
SW219866-1
EN300-19107
D02479
AB00052300_03
AB00052300_04
AB-601/30915002
SR-01000872739
Q2746995
SR-01000872739-1
BRD-K13421763-001-05-4
BRD-K13421763-001-06-2
BRD-K13421763-001-07-0
F2146-0059
Z104472798
202-511-6