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Tetrahydrothiophene

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Identification
Molecular formula
C4H8S
CAS number
110-01-0
IUPAC name
tetrahydrothiophene
State
State

At room temperature, tetrahydrothiophene is a liquid.

Melting point (Celsius)
-96.70
Melting point (Kelvin)
176.50
Boiling point (Celsius)
121.00
Boiling point (Kelvin)
394.00
General information
Molecular weight
88.18g/mol
Molar mass
88.1760g/mol
Density
0.9980g/cm3
Appearence

Tetrahydrothiophene is a colorless liquid with a characteristic odor. It is generally clear, with no color impurities visible to the naked eye.

Comment on solubility

Solubility of Tetrahydrothiophene (C4H8S)

Tetrahydrothiophene, also known as thiolan, is an interesting compound when it comes to solubility. Its solubility behavior can be summarized as follows:

  • Polar and Nonpolar Solvents: Tetrahydrothiophene is predominantly soluble in polar aprotic solvents such as acetone and alcohols, as well as nonpolar solvents like hexane due to its balanced molecular structure.
  • Water Solubility: While tetrahydrothiophene does have some degree of interaction with water, it is not considered significantly soluble in water because of its hydrophobic characteristics.
  • Temperature Dependency: Solubility can also change with temperature; generally, an increase in temperature will enhance the solubility of tetrahydrothiophene in various solvents.

It's important to note that the compounds' solubility can greatly affect its applications in chemical synthesis and industrial processes. As with many organic compounds, understanding solubility is crucial for safe and effective use.

Interesting facts

Exploring Tetrahydrothiophene

Tetrahydrothiophene is a fascinating organic compound that falls within the category of thiophenes, a group of compounds characterized by their sulfur-containing aromatic ring systems. Here are some interesting details about tetrahydrothiophene that showcase its significance:

  • Structure and Stability: Tetrahydrothiophene features a six-membered ring structure, which provides a unique balance of stability and reactivity. This structural configuration allows it to behave as a versatile intermediate in various chemical reactions.
  • Industrial Relevance: It serves as a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and different materials. Its presence can significantly enhance the performance characteristics of the final products.
  • Natural Occurrence: Tetrahydrothiophene has been identified in certain essential oils and is often noted for its contribution to the aroma and flavor of some natural products.
  • Reactivity with Electrophiles: As a compound rich in electrons due to the presence of sulfur, tetrahydrothiophene readily engages in electrophilic aromatic substitution reactions, making it a key player in synthesizing complex organic molecules.

To quote *Linus Pauling*, a renowned chemist: "The structure of a molecule is a critical factor in determining its properties." In the case of tetrahydrothiophene, its unique structure underpins its diverse applications, from medicinal chemistry to materials science.

This compound also underscores the importance of sulfur in organic chemistry—a reminder that often, the most intriguing compounds are those that break conventional boundaries.

Synonyms
tetrahydrothiophene
Thiolane
110-01-0
Thiophene, tetrahydro-
Thiophane
Thiacyclopentane
Tetramethylene sulfide
Thilane
Tetrahydrothiophen
Thiofan
Thiolan
Pennodorant 1013
Tetrahydrothiofen
Thiofan [Czech]
Tetramethylenesulfide
Pennodorant 1073
Tetrahydrothiofen [Czech]
NSC 5272
HSDB 6122
EINECS 203-728-9
UNII-744EHT13FM
UN2412
744EHT13FM
DTXSID3047760
CHEBI:48458
Tetramethylene sulphide
AI3-30989
NSC-5272
THT
TETRAHYDROTHIOPHENE [MI]
DTXCID8027743
EC 203-728-9
UN 2412
THT, thiophene
MFCD00005476
thiocyclopentane
tetrahydro-thiophene
thiophene, tetrahydro
Tetrahydrothiophene, 99%
CHEMBL1379
NSC5272
Tox21_304026
AKOS006220479
Tetrahydrothiophene, analytical standard
NCGC00357279-01
CAS-110-01-0
NS00003128
T0114
EN300-105780
Q412118
Tetrahydrothiophene [UN2412] [Flammable liquid]
203-728-9