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Tetrahydrofuran-3-yl N-[3-[(4-aminophenyl)sulfonyl-isobutyl-amino]-1-benzyl-2-hydroxy-propyl]carbamate

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Identification
Molecular formula
C26H34N2O6S
CAS number
140283-79-0
IUPAC name
tetrahydrofuran-3-yl N-[3-[(4-aminophenyl)sulfonyl-isobutyl-amino]-1-benzyl-2-hydroxy-propyl]carbamate
State
State

At room temperature, this compound typically exists as a viscous liquid. It is stable under recommended storage conditions and should be kept away from heat sources and direct sunlight.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
455.65
Boiling point (Kelvin)
728.80
General information
Molecular weight
472.59g/mol
Molar mass
472.5850g/mol
Density
1.2400g/cm3
Appearence

The compound is typically a colorless, viscous liquid. It may appear somewhat oily and presents a faint smell characteristic of amines.

Comment on solubility

Solubility of Tetrahydrofuran-3-yl N-[3-[(4-aminophenyl)sulfonyl-isobutyl-amino]-1-benzyl-2-hydroxy-propyl]carbamate

The solubility of the compound with the formula C26H34N2O6S, commonly known as tetrahydrofuran-3-yl N-[3-[(4-aminophenyl)sulfonyl-isobutyl-amino]-1-benzyl-2-hydroxy-propyl]carbamate, can be assessed by examining several factors:

  • Polar Functional Groups: This compound contains several polar functional groups such as carbamate and sulfonyl, which contribute to its solubility in polar solvents.
  • Hydrophobic Characteristics: The presence of a bulky benzyl group may introduce hydrophobic characteristics, making it less soluble in water.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents like ethanol, methanol, or even acetone due to its non-polar pathways.
  • Temperature Dependence: As with many organic compounds, solubility may increase with temperature, suggesting that heating could enhance solubility in suitable solvents.

In conclusion, the solubility of this compound seems to be versatile, exhibiting higher solubility in organic solvents compared to water, which is a common trait for many similar compounds. Understanding these solubility characteristics is crucial for applications in the pharmaceutical industry, as they influence formulation and delivery mechanisms.

Interesting facts

Interesting Facts about Tetrahydrofuran-3-yl N-[3-[(4-aminophenyl)sulfonyl-isobutyl-amino]-1-benzyl-2-hydroxy-propyl]carbamate

This unique compound exhibits a fascinating molecular architecture, making it a noteworthy subject of study in medicinal and organic chemistry. Here are several compelling aspects:

  • Multifunctional Characteristics: The compound includes both a tetrahydrofuran segment and a carbamate moiety, which are known for their roles in enhancing solubility and biological activity. This multifunctionality allows for tailored applications within pharmaceutical contexts.
  • Potential Therapeutic Applications: Due to its structural resemblance to various pharmaceutical agents, it potentially serves as a scaffold in drug design. Compounds like these are often investigated for their ability to inhibit certain enzymes or act on biological targets.
  • Complex Synthesis: The synthetic pathway to create such a compound may involve advanced techniques like protecting group strategies and coupling reactions. This complexity opens avenues for innovation in organic synthesis and offers an educational platform for students.
  • Intermolecular Interactions: The presence of sulfonamide groups suggests enhanced hydrogen-bonding capabilities, which can influence the compound's physical properties and reactivity, thus making it a point of interest in intermolecular interactions studies.
  • Biological Insights: Structurally rich compounds such as this can provide insight into structure-activity relationships, an essential area in drug discovery that explores how variations in molecular composition can affect biological outcomes.

In conclusion, the exploration of tetrahydrofuran-3-yl N-[3-[(4-aminophenyl)sulfonyl-isobutyl-amino]-1-benzyl-2-hydroxy-propyl]carbamate highlights the intersection of synthetic strategy and therapeutic potential, making it a prominent candidate for further research. As noted by an esteemed researcher in the field, “The complexity of such compounds is a testament to the beauty of chemical synthesis and its implications for human health.”

Synonyms
CHEMBL195725
SCHEMBL7287657
DTXSID30861429
HMS3655K13
{3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER
BDBM50163391
SB19589
LS-15128
DB-043501
Oxolan-3-yl {4-[(4-aminobenzene-1-sulfonyl)(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate