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Sodium oxamate

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Identification
Molecular formula
NaC2H2NO3
CAS number
6131-90-4
IUPAC name
sodium;oxamate
State
State

At room temperature, sodium oxamate is typically seen as a solid.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
111.02g/mol
Molar mass
111.0220g/mol
Density
2.2657g/cm3
Appearence

Sodium oxamate typically appears as a white, crystalline powder. It is often encountered in its sodium salt form, either as an anhydrous solid or as a hydrate, depending on the environmental conditions.

Comment on solubility

Solubility of Sodium Oxamate (NaC2H2NO3)

Sodium oxamate, known by its chemical formula NaC2H2NO3, is a fascinating compound when it comes to solubility. Understanding its behavior in different solvents can provide insight into its practical applications:

  • Water Solubility: Sodium oxamate is highly soluble in water. This property stems from its ionic nature, which allows it to interact effectively with polar water molecules.
  • Solvent Variability: While it is predominantly soluble in aqueous solutions, the solubility in other solvents may vary. For instance, it may have limited solubility in organic solvents like ethanol or methanol.
  • Temperature Dependency: The solubility of sodium oxamate can also be influenced by temperature. Generally, an increase in temperature can lead to an increase in solubility.
  • Effect of pH: The solubility may be affected by the pH of the solution, as changes can alter the ionization state of the compound, potentially enhancing its solubility at certain pH levels.

In summary, sodium oxamate exhibits remarkable solubility in water, making it readily available for various chemical processes. As with many compounds, its solubility characteristics can vary based on solvent type, temperature, and pH, allowing for diverse applications in both academia and industry.

Interesting facts

Interesting Facts about Sodium Oxamate

Sodium oxamate is a fascinating compound with significant applications in biochemistry and medical research. This sodium salt forms when oxamic acid, a derivative of oxalic acid, reacts with sodium ions.

Significance in Biochemistry

  • Enzyme Inhibitor: Sodium oxamate is widely recognized for its role as an inhibitor of lactate dehydrogenase, an important enzyme in the metabolic pathway that leads to the production of lactate.
  • Clinical Research: It has drawn attention in studies concerning cancer metabolism, where the regulation of lactate production can be crucial for therapeutic strategies.
  • Metabolic Regulation: This compound also plays a part in investigating the effects of glucose metabolism and its relationship to various health conditions.

Applications and Uses

  • Drug Development: Sodium oxamate's inhibitory properties are explored in the development of novel anticancer agents.
  • Research Tool: Scientists utilize it to manipulate lactate levels in biological studies and understand metabolic pathways better.

Overall, sodium oxamate stands out not just as a chemical compound but as a valuable tool in advancing our understanding of biochemical processes and therapeutic innovations. The compound exemplifies how simple alterations in molecular structure can lead to profound effects in biological systems. As the renowned chemist Linus Pauling once said, "The best way to have a good idea is to have lots of ideas," and sodium oxamate certainly opens the door to numerous research possibilities.

Synonyms
sodium oxamate
565-73-1
Oxamic acid sodium salt
Sodium 2-amino-2-oxoacetate
Oxamic acid, sodium salt
Aminooxoacetic acid sodium salt
Acetic acid, aminooxo-, monosodium salt
sodium;oxamate
Oxamate (sodium)
MFCD00044553
Oxamic acid (sodium)
EINECS 209-290-5
Acetic acid, 2-amino-2-oxo-, sodium salt (1:1)
Oxalic acid monoamide sodium salt
Lopac-O-2751
SCHEMBL2370295
CHEMBL1256289
DTXSID1060342
RQVZIJIQDCGIKI-UHFFFAOYSA-M
HMS3262H08
HY-W013032A
Tox21_500913
BDBM50144744
AKOS024462579
CCG-222217
FS35024
LP00913
NCGC00016183-01
NCGC00016183-02
NCGC00094224-01
NCGC00261598-01
SY021553
DB-052941
CS-0109107
EU-0100913
NS00080022
O 2751