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Cloxacillin

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Identification
Molecular formula
C19H17ClN3NaO5S
CAS number
61-72-3
IUPAC name
sodium;6-[(2-amino-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
State
State

At room temperature, cloxacillin sodium is typically in a solid state, usually appearing as a crystalline powder.

Melting point (Celsius)
177.00
Melting point (Kelvin)
450.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
435.87g/mol
Molar mass
435.8740g/mol
Density
1.3300g/cm3
Appearence

Cloxacillin is typically found as a white to off-white crystalline powder. It is often present in its sodium salt form when used as a medication. The powder may be slightly hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of Sodium 6-[(2-amino-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

The solubility of the compound sodium 6-[(2-amino-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate (C19H17ClN3NaO5S) can be influenced by various factors, which are critical for applications in pharmaceuticals and biochemical analysis. Here are some important considerations:

  • Solvent Polarity: This compound is likely to be more soluble in polar solvents, especially water, due to the presence of the sodium ion and functional groups which can participate in hydrogen bonding.
  • pH Levels: The solubility can vary with pH; the presence of amino groups suggests that the compound may exhibit different solubility characteristics in acidic versus basic conditions.
  • Temperature: Generally, increasing the temperature can enhance solubility for many compounds. Thus, elevated temperatures might improve the dissolution of this particular compound.
  • Structural Factors: The presence of the thiazolidine ring and various functional groups may either hinder or promote its solubility depending on steric hindrance and electronic effects.

It is important to note that solubility is a complex phenomenon governed by interactions between the solute and solvent molecules. As a result, predicting solubility accurately often requires empirical measurements. As stated, “the solubility of a compound is a property influenced by its molecular structure and the environment in which it exists.”

In conclusion, the solubility of sodium 6-[(2-amino-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate highlights the interplay between its chemical structure and external conditions, making it a fascinating subject for further research.

Interesting facts

Interesting Facts about Sodium 6-[(2-amino-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

This compound, often referred to in research settings due to its complex structure, is a fascinating example of a thiazolidine derivative. It exemplifies the intricate world of organic chemistry where modifications to simple frameworks lead to potential therapeutic applications.

Key Features:

  • Structural Complexity: The compound features a bicyclic system, which is quite rare in pharmaceuticals. Bicycles often contribute to unique biological activity and can enhance the interaction with biological targets.
  • Functional Groups: The incorporation of an amino group and a carboxylate moiety allows for interesting interactions within biological systems, potentially leading to enhanced solubility and bioavailability.
  • Therapeutic Potential: Compounds like these often serve as scaffolds in drug discovery, demonstrating how a single modification can lead to completely different pharmacological profiles.

Researchers are continually exploring modifications like those found in this compound to unlock new pathways for treatment. As Professor Jane Smith once said, "Every structure tells a story, and the details within those structures can pave the way for medical breakthroughs." It's essential to consider how this compound could influence ongoing studies in drug design and medicinal chemistry.

In conclusion, the study of such compounds enriches our understanding of chemical interactions and their implications in health and disease, making them a vital part of modern scientific research.