Sodium dexamethasone phosphate | Solubility of Things

Identification

Molecular formula

C₂₂H₂₈FNaO₈

CAS number

55203-24-2

IUPAC name

sodium;4-[2-[(5R,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethoxy]-4-oxo-butanoate

State

Sodium dexamethasone phosphate is typically found in a solid state at room temperature. As a stable, crystalline powder, it exhibits a robust shelf life under appropriate storage conditions, away from moisture and heat.

Melting point (Celsius)

233.00

Melting point (Kelvin)

506.15

Boiling point (Celsius)

398.00

Boiling point (Kelvin)

671.15

General information

Molecular weight

516.41g/mol

Molar mass

516.4140g/mol

Density

1.2600g/cm³

Appearence

Sodium dexamethasone phosphate is generally found as a white or almost white crystalline powder. It is highly soluble in water, which makes it suitable for injection formulations. The compound is characterized by its absence of color and strong purity when appropriately synthesized.

Comment on solubility

Solubility of Sodium 4-[2-[(5R,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethoxy]-4-oxo-butanoate

The solubility of sodium 4-[2-[(5R,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethoxy]-4-oxo-butanoate, represented by the formula C₂₂H₂₈FNaO₈, can be influenced by various factors, such as temperature, pH, and the presence of other ions in solution.

In general, when considering the solubility of such a complex aromatic compound, it is important to note that:

Sodium salts often exhibit enhanced solubility in water due to the ionic nature of sodium, which facilitates dissociation in aqueous solutions.
The functional groups present in the compound may contribute to its solubility characteristics. For instance, carboxylic acid groups often increase water solubility.
The hydrophobic regions of the molecule may hinder solubility in polar solvents, leading to a potential preference for non-polar environments.

Furthermore, in biological systems, the solubility can be markedly different from standard laboratory conditions. As highlighted by researchers, "the solubility behavior often dictates bioavailability and the compound's overall activity."

Overall, while sodium 4-[2-[(5R,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethoxy]-4-oxo-butanoate may have a varied solubility profile, understanding its solubility is crucial for its application in medicinal chemistry and pharmacology.

Interesting facts

Interesting Facts About Sodium 4-[2-[(5R,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethoxy]-4-oxo-butanoate

This compound, recognized for its intricate structure and biological relevance, presents peculiar opportunities and challenges for chemists and biologists alike. Here are some fascinating aspects:

Complex Structure: The molecule features multiple stereocenters, making it a chiral compound. This complexity can result in different biological activities based on its enantiomers.
Application in Medicinal Chemistry: Given its structural resemblance to steroid-like compounds, it has potential applications in pharmaceuticals, particularly in hormone therapy and anti-inflammatory agents.
Biological Interactions: The molecular configuration allows for interactions with specific biological receptors, enabling the exploration of new therapeutic pathways.
Study of Synthesis: The synthetic pathways to create such a compound are of great interest; the formation of carbon-carbon bonds in the synthesis presents challenges that inform new techniques in organic chemistry.
Contributions to Material Science: Beyond its biological implications, the compound could extend to material science, potentially serving as a precursor for biodegradable polymers.

As famed chemist Linus Pauling once said, "The best way to have a good idea is to have a lot of ideas." This substance exemplifies the intersection of various fields and underscores the importance of interdisciplinary research.
In conclusion, the exploration of Sodium 4-[2-[(5R,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethoxy]-4-oxo-butanoate reveals a wealth of potential and complexity that is bound to intrigue upcoming scientists and experienced researchers alike.