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Penicillin G sodium

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Identification
Molecular formula
C16H17N2NaO4S
CAS number
69-57-8
IUPAC name
sodium;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
State
State
At room temperature, Penicillin G sodium is typically in powder form and is used in solution for injection. It is generally stable if kept in an appropriate dry environment.
Melting point (Celsius)
199.50
Melting point (Kelvin)
472.65
Boiling point (Celsius)
150.00
Boiling point (Kelvin)
423.15
General information
Molecular weight
356.39g/mol
Molar mass
356.3900g/mol
Density
1.3300g/cm3
Appearence

Penicillin G sodium appears as a white or almost white crystalline powder. It is known for being odorless, although it may have a faint odor if any at all. Due to its crystalline nature, it is typically provided in a powdered form for use in various medical applications.

Comment on solubility

Solubility of Sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate (C16H17N2NaO4S)

The solubility of sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate is influenced by various factors due to its complex structure. Here are some key points regarding its solubility:

  • Sodium Salt Form: As a sodium salt, this compound is likely to exhibit good solubility in polar solvents like water. Sodium salts generally tend to dissolve well due to the ionic nature of sodium ions, which can stabilize interactions with water molecules.
  • Polarity: The presence of both amine and carboxylate functional groups enhances the polarity of the compound, contributing to its solubility in aqueous environments.
  • Hydrophobic Groups: The phenylacetyl moiety introduces hydrophobic characteristics, which can limit solubility in non-polar solvents. Conversely, this hydrophobicity can also lead to enhanced solubility in mixed-solvent systems or when used in formulations that mask its hydrophobic effects.
  • Temperature Dependency: Like many compounds, solubility may increase with temperature. This is important to consider in both laboratory settings and potential applications.

In summary, the solubility of C16H17N2NaO4S is determined by a balance of its ionic properties, functional group interactions, and temperature conditions. Understanding these factors is essential for optimizing its use in various applications.

Interesting facts

Interesting Facts about (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

This fascinating compound, commonly known as a sodium salt derivative, belongs to a class of organic compounds that exhibit significant biological properties. Here are some intriguing facts that highlight its importance:

  • Pharmaceutical Applications: This compound is often featured in the development of antibiotics and anti-inflammatory drugs, showcasing its potential in medicinal chemistry.
  • Mechanism of Action: The unique bicyclic structure plays a critical role in its ability to interact with biological systems, which can lead to inhibition of specific enzymes or receptors, making it a point of interest in pharmacology.
  • Synthetic Pathways: The synthesis of this compound often involves multi-step reactions, utilizing various reagents and conditions. Understanding these synthetic pathways is essential for producing it efficiently and safely.
  • Structure-Activity Relationship (SAR): Researchers rigorously study the structure of this compound to identify how slight modifications can enhance its efficacy or reduce side effects, driving innovations in drug design.
  • Environmental Concerns: As with many pharmaceutical compounds, its environmental impact is under scrutiny, especially in terms of metabolic byproducts and persistence in ecosystems, prompting studies in green chemistry.

In the realm of organic synthesis and medicinal chemistry, the versatility and complexity of such compounds provide endless possibilities for research and development. As one scientist noted, "The beauty of organic compounds lies in their ability to yield innovative solutions to medicinal challenges."

Overall, compounds like this one are at the forefront of chemical research, combining aspects of organic chemistry, pharmacology, and environmental science in their study and application.