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Sodium Ceftazidime

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Identification
Molecular formula
C22H22N6NaO7S4
CAS number
72558-82-8
IUPAC name
sodium;2-methyl-3-[(5-methylthiazol-2-yl)carbamoyl]-1,1-dioxo-1lambda6,2-benzothiazin-4-olate
State
State

At room temperature, sodium ceftazidime is in a solid state, typically available in the form of powder for industrial and pharmaceutical applications.

Melting point (Celsius)
93.00
Melting point (Kelvin)
366.15
Boiling point (Celsius)
160.00
Boiling point (Kelvin)
433.15
General information
Molecular weight
546.58g/mol
Molar mass
546.5790g/mol
Density
1.5580g/cm3
Appearence

Sodium ceftazidime is typically supplied as a white to light yellow crystalline powder. It is odorless and is hygroscopic, meaning it can absorb moisture from the environment.

Comment on solubility

Solubility of Sodium 2-methyl-3-[(5-methylthiazol-2-yl)carbamoyl]-1,1-dioxo-1lambda6,2-benzothiazin-4-olate

The solubility of the compound sodium 2-methyl-3-[(5-methylthiazol-2-yl)carbamoyl]-1,1-dioxo-1lambda6,2-benzothiazin-4-olate (C22H22N6NaO7S4) can be influenced by various factors. Understanding these can be crucial for various applications in chemical processes, drug formulation, and material science. Here are some key points to consider:

  • Polarity: The compound contains multiple functional groups, which can enhance its polarity. This increased polarity often results in higher solubility in polar solvents, particularly water.
  • Ionic Nature: The presence of sodium (Na) suggests that this compound has an ionic aspect, which generally leads to good solubility in aqueous solutions.
  • Hydrogen Bonding: Various moieties, especially the thiazole and amide groups, may participate in hydrogen bonding, further enhancing solubility in water.
  • pH Levels: The solubility may also be affected by the pH of the solution. A more acidic or basic environment can potentially alter the ionization state of the compound, thus impacting its solubility.

In summary, it is likely that sodium 2-methyl-3-[(5-methylthiazol-2-yl)carbamoyl]-1,1-dioxo-1lambda6,2-benzothiazin-4-olate exhibits good solubility in water due to its ionic characteristics and polarity. However, specific solubility tests would be necessary to provide quantitative data and confirm these properties in practice.

Interesting facts

Interesting Facts about Sodium; 2-Methyl-3-[(5-methylthiazol-2-yl)carbamoyl]-1,1-dioxo-1lambda6,2-benzothiazin-4-olate

This compound, a fascinating example of modern chemistry, possesses unique properties and potential applications that make it noteworthy in the field of pharmaceutical research. Here are some interesting points to consider:

  • Complex Structure: The compound's structure incorporates a benzothiazine moiety, which is known for its biological activity. This complexity can influence its pharmacodynamics and interactions with biological systems.
  • Biological Importance: Compounds like this one are often designed to target specific biological pathways. Its thiazole and carbamate groups may play significant roles in enhancing activity against certain diseases or conditions.
  • Potential Therapeutic Uses: Researchers are increasingly exploring compounds such as this one for their potential in developing treatments for bacterial infections and possibly even cancer, given the presence of unique reactive sites that may modulate enzyme activity.
  • Research and Development: Interest in compounds like this particular benzothiazine derivative highlights the importance of modifying existing chemical structures to improve efficacy and reduce side effects in therapeutic agents.
  • Analytical Techniques: Investigating the properties of this compound often involves sophisticated analytical techniques, including NMR spectroscopy and mass spectrometry, enabling scientists to determine structural integrity and explore its reactivity.

Overall, the sodium; 2-methyl-3-[(5-methylthiazol-2-yl)carbamoyl]-1,1-dioxo-1lambda6,2-benzothiazin-4-olate stands as a testament to the innovative directions in medicinal chemistry, offering insights into how small structural modifications can lead to significant advances in drug design. The evolution of such compounds continues to expand the horizon of therapeutic possibilities.

Synonyms
Meloxicam sodium
MELOXICAM (SODIUM)
DTXSID601017452
Sodium 2-methyl-3-((5-methylthiazol-2-yl)carbamoyl)-2H-benzo[e][1,2]thiazin-4-olate 1,1-dioxide
NCGC00015671-01
Lopac-M-3935
MLS002153247
CHEMBL1256873
HY-B0261A
DTXCID401476248
HMS2094I11
HMS2235M13
HMS3262I14
HMS3369C08
Tox21_500766
CCG-204851
CCG-213268
LP00766
SDCCGSBI-0050744.P002
NCGC00015671-02
NCGC00015671-03
NCGC00015671-04
NCGC00094105-01
NCGC00094105-02
NCGC00261451-01
SMR001230703
CS-0013662
EU-0100766
M 3935
EN300-37299900
sodium 2-methyl-3-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]-1,1-dioxo-2H-1lambda6,2-benzothiazin-4-olate