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(S)-(6-Methoxy-4-quinolyl)-[(2R,5R)-5-vinylquinuclidin-2-yl]methanol

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Identification
Molecular formula
C21H26ClN2O
CAS number
37576-25-9
IUPAC name
(S)-(6-methoxy-4-quinolyl)-[(2R,5R)-5-vinylquinuclidin-2-yl]methanol
State
State

At room temperature, this compound is a solid. It is often found in a crystalline powder form, which is stable under normal conditions of storage and handling.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
560.20
Boiling point (Kelvin)
833.30
General information
Molecular weight
345.43g/mol
Molar mass
345.4340g/mol
Density
1.0800g/cm3
Appearence

This compound appears as a solid substance, typically presented as yellow crystals or powder. It may change its color slightly depending on the purity and specific form in which it is prepared.

Comment on solubility

Solubility of (S)-(6-methoxy-4-quinolyl)-[(2R,5R)-5-vinylquinuclidin-2-yl]methanol

The solubility of the compound (S)-(6-methoxy-4-quinolyl)-[(2R,5R)-5-vinylquinuclidin-2-yl]methanol, with the chemical formula C21H26ClN2O, can be quite intriguing due to its structural complexity and various functional groups. Understanding the solubility of such compounds is crucial for their applications in pharmaceutical and chemical industries. Here are some key points to consider:

  • Polar vs. Non-Polar Solvents: Typically, compounds containing hydroxyl groups (–OH), like this one due to the methanol moiety, tend to be more soluble in polar solvents such as water. However, the presence of hydrophobic aromatic and aliphatic sections can impede solubility in highly polar solvents.
  • Influence of Temperature: Solubility can also be temperature-dependent; generally, increasing temperature enhances solubility for many organic compounds. Thus, evaluating solubility at different temperatures can provide more insights.
  • pH Sensitivity: pH can influence the solubility of compounds that can ionize. If any components in this compound can deprotonate or protonate, their solubility can vary significantly across different pH levels.
  • Crystallinity: The degree of crystallinity in the compound also greatly affects solubility. Amorphous compounds typically exhibit higher solubility than their crystalline counterparts.

In summary, the solubility of C21H26ClN2O should be explored in various solvents and conditions to fully understand its behavior. As a general rule, compounds with intricate structures usually present unique solubility profiles, and thus, empirical testing is often necessary.

Interesting facts

Interesting Facts about (S)-(6-methoxy-4-quinolyl)-[(2R,5R)-5-vinylquinuclidin-2-yl]methanol

This intriguing compound, often referred to for its complex structure, belongs to the category of quinoline derivatives. Its multifaceted arrangement not only creates a unique molecular profile but also garners interest in various research fields.

Key Characteristics

  • Stereochemistry: The presence of specific stereochemical configurations, indicated by (S) and (R) notations, suggests that this compound exhibits chirality, making it a vital subject in studies involving enantiomers and their biological interactions.
  • Potential Pharmacological Applications: Compounds containing both quinoline and quinuclidine structures have been investigated for their potential as therapeutic agents. This compound's unique combination of features hints at possible activity against certain diseases, attracting the attention of medicinal chemists.
  • Structure-Activity Relationship (SAR): Chemists are often keen to explore how modifications in molecular structure impact biological activity. This compound serves as an excellent model for SAR studies due to its complex functional groups.

Scientific Exploration

Discovery and development of such compounds typically arise from a desire to create new therapies targeting specific receptors or enzymes. The design of (S)-(6-methoxy-4-quinolyl)-[(2R,5R)-5-vinylquinuclidin-2-yl]methanol offers a window into the intricate workings of drug design, where subtle changes to the molecule can lead to significant impacts on efficacy.

In the words of a prominent medicinal chemist, "Understanding the structure is key to unlocking the potential of new drugs." This emphasizes the compound's importance not just in its isolated form, but as a potential candidate for further research and therapeutic development.

In summary, the exploration of (S)-(6-methoxy-4-quinolyl)-[(2R,5R)-5-vinylquinuclidin-2-yl]methanol exemplifies the combination of complexity and promise that defines modern chemical research. Its unique features could pave the way for discovering innovative solutions in pharmacology.

Synonyms
Quinidine sulfate
(S)-[(2R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol
Quinaglute
SR-01000075163
Quinidine (BAN)
Kinidin (TN)
Prestwick0_000280
Prestwick1_000280
Prestwick2_000280
Lopac0_001009
BSPBio_001467
SPBio_002379
SCHEMBL2760464
SCHEMBL17664740
GNF-PF-5459
CHEBI:182417
LOUPRKONTZGTKE-NBGVHYBESA-N
HMS1989J09
BDBM50410855
C06527
D08458
EN300-24442275
SR-01000075163-1
SR-01000075163-5
BRD-A17470778-001-02-9
(S)-[(2R,5R)-5-ETHENYL-1-AZABICYCLO[2.2.2]OCTAN-2-YL](6-METHOXYQUINOLIN-4-YL)METHANOL
1234784-40-7