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Poly(A) polymerase gamma

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Identification
Molecular formula
C43H70N7O18P3S
CAS number
134918-20-8
IUPAC name
S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] octadeca-9,12-dienethioate
State
State

At room temperature, this compound typically exists in a solid state. It is stable under standard conditions and does not easily convert to other states without significant energy input.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
362.00
Boiling point (Kelvin)
635.15
General information
Molecular weight
789.80g/mol
Molar mass
789.7600g/mol
Density
1.6500g/cm3
Appearence

The compound is generally observed as a white or off-white powder. It is not very soluble in water and has a crystalline structure characteristic of many organic compounds with complex side chains.

Comment on solubility

Solubility of S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] octadeca-9,12-dienethioate (C43H70N7O18P3S)

The solubility of this complex compound is influenced by various structural features, making it quite intriguing. As a rule of thumb, the solubility of compounds typically depends on:

  • Polarity: Given the presence of multiple hydroxyl (-OH) groups and phosphate moieties, this compound exhibits a degree of polarity that can contribute to its solubility in polar solvents such as water.
  • Functional Groups: The presence of amino and phosphonic acid groups tends to enhance solubility in aqueous environments.
  • Hydrophobic Regions: The octadeca chain introduces a hydrophobic element that might limit solubility in water but may allow for solubility in organic solvents.
  • pH Dependency: Solubility may also vary with changes in pH, especially accounting for the ionic nature of phosphate groups, influencing their protonation state.

Overall, it can be stated that this compound is likely to be soluble in polar solvents while showing limited solubility in non-polar solvents due to its intricate balance of hydrophilic and hydrophobic characteristics. Understanding these solubility properties is crucial for its potential applications in biochemical contexts.

Interesting facts

Interesting Facts about S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] octadeca-9,12-dienethioate

This complex compound, with its intricate structure, is a remarkable example of modern organic chemistry and biotechnology. It is a derivative in the field of nucleotide chemistry, where the fusion of multiple functional groups often leads to enhanced biological activities and applications. Here are some fascinating aspects of this compound:

  • Bioactivity: Compounds like this one often play a critical role in pharmacology, functioning as potential therapeutic agents that may target specific cellular mechanisms.
  • Design Complexity: The assembly of such a molecule showcases the intricate designs chemists must consider. The careful placement of various substituents can significantly affect the compound's biological behavior.
  • Potential Uses: Due to its structural similarities with nucleotide and nucleoside analogs, this compound could potentially be explored for its antiviral or anticancer properties.
  • Synthetic Pathways: The synthesis of such a compound often involves multiple steps, incorporating strategies from combinatorial chemistry to optimize yield and selectivity.

The molecule also features a variety of chemical functionalities, including:

  • Aminopurines
  • Hydroxy groups
  • Phosphoryl groups
  • Sulfonate esters

As stated by renowned chemists in the field, "Innovation in molecular design could lead to unprecedented capabilities in biomedicine." The research surrounding compounds like this can bridge gaps between synthetic chemistry and practical medical applications.

Overall, the structural and functional diversity of such compounds emphasizes the *importance of interdisciplinary approaches* in chemistry. Understanding these intricate molecules not only enhances our knowledge of chemical interactions but also paves the way for future therapeutic innovations.