Skip to main content

S-adenosylmethionine

ADVERTISEMENT
Identification
Molecular formula
C15H22N6O5P
CAS number
29908-03-0
IUPAC name
S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] tetradecanethioate
State
State

At room temperature, S-adenosylmethionine is usually found as a solid. It is often in powder form for supplements or research purposes and should be preserved in a moisture-free environment to retain its stability and efficacy.

Melting point (Celsius)
50.00
Melting point (Kelvin)
323.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
398.44g/mol
Molar mass
398.4380g/mol
Density
1.2300g/cm3
Appearence

S-adenosylmethionine (SAMe) typically appears as a white powder. It is hygroscopic, meaning it can absorb moisture from the air, and thus, it should be stored properly to prevent any change in its consistency or appearance.

Comment on solubility

Solubility of S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] tetradecanethioate

The solubility characteristics of the compound S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] tetradecanethioate (C15H22N6O5P) can be interestingly complex due to its structural makeup. Here are some key points to consider:

  • Hydrophilicity: The presence of hydrophilic groups such as phosphate and amino functionalities may contribute to a certain degree of water solubility.
  • Hydrophobic Interactions: The tetradecanethioate group suggests potential for hydrophobic interactions, which could lead to reduced solubility in polar solvents.
  • pH Dependency: Solubility may vary significantly with changes in pH, especially due to the ionizable groups present; this warrants careful consideration in different environments.
  • Concentration Factors: The saturation point may be substantially impacted by concentration, affecting solubility profiles when dissolved in solvents.

In summary, while some components may lend to water solubility, the overall complex structure of this compound points to a nuanced interaction that can lead to varying solubility in different solvents. As with many biological and pharmaceutical compounds, empirically determined solubility data would be vital for practical applications.


Interesting facts

Interesting Facts about S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] tetradecanethioate

This compound is a fascinating example of a complex molecular structure that demonstrates the intricate relationships between various functional groups and their biological significance. It represents a class of compounds that are often involved in important biochemical processes such as cellular signaling and metabolism.

Here are some insights into this remarkable compound:

  • Multifunctional Groups: The presence of multiple phosphoryl and amino groups suggests that this compound might play a role in energy transfer processes or enzyme regulation.
  • Potential Therapeutic Applications: Compounds containing purine derivatives like 6-aminopurine have been studied for their potential in treating various diseases due to their ability to mimic natural nucleotides.
  • Structural Complexity: The compound's long carbon chain (tetradecanethioate) hints at its possible applications in lipid biochemistry and may influence its interactions within biological membranes.
  • Hydroxyl Functionalities: The myriad hydroxyl (-OH) groups suggest high polarity, which could affect solubility and interaction with biomolecules, making it interesting for research in drug formulation.

As a member of a larger class of compounds, it is crucial to study such complex molecules to understand their roles and mechanisms in biological systems. As noted by many researchers, "the structure of a molecule often holds the key to its function," highlighting the significance of chemical structure in real-world applications.

In summary, this compound is not just a random arrangement of atoms but a potential key player in understanding biochemical pathways and the development of new therapeutic strategies. Its intricate features make it a subject of interest for chemists and biochemists alike.

Synonyms
Myristoyl coenzyme A
3130-72-1
myristoylCoA
Myristoyl coenzyme A sodium salt
BCP31960
S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] tetradecanethioate
Tetradecanoyl-CoA;Myristoyl-CoA;S-Tetradecanoyl-coenzyme A