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Amiprilose

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Identification
Molecular formula
C21H36N7O16P3S
CAS number
105505-60-8
IUPAC name
S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] 2-methylpropanethioate
State
State
Amiprilose is generally in a solid state at room temperature, maintaining its form as a crystalline powder.
Melting point (Celsius)
229.00
Melting point (Kelvin)
502.15
Boiling point (Celsius)
150.00
Boiling point (Kelvin)
423.15
General information
Molecular weight
691.73g/mol
Molar mass
691.7330g/mol
Density
1.7000g/cm3
Appearence
Amiprilose typically appears as a white crystalline powder. This physical form is common for many pharmaceuticals and aids in its identification.
Comment on solubility

Solubility of S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] 2-methylpropanethioate

This compound, with the chemical formula C21H36N7O16P3S, exhibits unique solubility characteristics influenced by its complex structure. The solubility of such large and multi-functional organic molecules often presents an intriguing profile:

  • Polarity: The presence of multiple hydroxyl (-OH) and phosphate groups within the compound increases its polarity, which can enhance solubility in polar solvents such as water.
  • Functional Groups: The amino and thioate functional groups are known to interact favorably with solvents, potentially improving overall solubility.
  • Hydrophobic Regions: Conversely, parts of the molecule, particularly the hydrocarbon chains, may create hydrophobic regions that can limit solubility in water.
  • pH Dependence: The solubility may also change with pH as the protonation state of the amino and phosphate groups alters, impacting their ability to interact with solvents.
  • Solvent Systems: It may exhibit better solubility in mixed solvent systems, particularly those combining both polar and nonpolar characteristics.

To summarize, while one might anticipate varying solubility profiles due to its diverse functional groups, understanding the balance between hydrophobic and hydrophilic interactions is key. Remember, as the famous quote goes: "Solubility is not just a number; it’s a balance of forces."

Interesting facts

Interesting Facts about S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] 2-methylpropanethioate

This compound holds an intriguing position in biochemistry due to its complex structure and potential biological activities. Here are some fascinating facets of this chemical:

  • Biological Relevance: This compound features the purine base 6-aminopurine, which is known for its role in various biochemical pathways, including nucleic acid metabolism.
  • Phosphorylation Importance: The presence of multiple phosphate groups in its structure is significant, as phosphorylation is a crucial process for signal transduction and regulation in cellular functions.
  • Addressing Health: Given its intricate design, this compound may offer insights into therapeutic applications, particularly in treating conditions related to purine metabolism.
  • Structural Complexity: With over 20 atoms and a variety of functional groups including hydroxyl and thioate functional groups, this molecule exemplifies the chemical diversity often found in biologically active compounds.
  • Synthetic Pathways: The synthesis of such compounds often requires specialized techniques and knowledge in organic synthesis, demonstrating the intersection of chemistry and pharmacology.

Furthermore, it is worth noting how compounds like this can sometimes exhibit unexpected properties or interactions that make them valuable in research. As with many compounds in the realm of biochemistry, the pursuit of understanding their mechanisms can lead to groundbreaking discoveries in medicine and biotechnology.

In summary, this compound is a prime candidate for further study, where its complex nature may unveil new avenues in scientific research and therapeutic interventions.

Synonyms
SCHEMBL120458
DTXSID00864609
NS00120045
Q943828
S-{1-[5-(6-Amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5,10,14-tetraoxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} 2-methylpropanethioate