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Quinoline-2-carboxylic acid

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Identification
Molecular formula
C10H7NO2
CAS number
89-00-9
IUPAC name
quinoline-2-carboxylic acid
State
State

Quinoline-2-carboxylic acid is a solid at room temperature. It is typically found in the form of crystalline powder.

Melting point (Celsius)
208.00
Melting point (Kelvin)
481.15
Boiling point (Celsius)
465.00
Boiling point (Kelvin)
738.15
General information
Molecular weight
173.16g/mol
Molar mass
173.1580g/mol
Density
1.2087g/cm3
Appearence

Quinoline-2-carboxylic acid is presented as a light yellow to yellow solid with a crystalline appearance. It may exhibit a slight odor, characteristic of aromatic carboxylic acids. The compound is stable at room temperature, but should be stored away from light to prevent degradation.

Comment on solubility

Solubility of Quinoline-2-Carboxylic Acid

Quinoline-2-carboxylic acid is an interesting compound with unique solubility characteristics in various solvents. Its solubility can be attributed to its molecular structure, which includes both a quinoline and a carboxylic acid functional group. Below are some crucial points regarding its solubility:

  • Polar Solvents: Quinoline-2-carboxylic acid is generally soluble in polar solvents such as water and methanol. The presence of the carboxylic acid group enhances its ability to form hydrogen bonds with water molecules.
  • Non-Polar Solvents: In contrast, this compound has limited solubility in non-polar solvents like hexane. The hydrophobic quinoline ring tends to resist dissolution in non-polar environments.
  • pH Dependence: The solubility is also pH-dependent. At higher pH levels, the carboxylic acid can deprotonate, increasing its solubility in aqueous solutions because of the ionic form created.
  • Temperature Influence: Increasing the temperature generally leads to enhanced solubility in most solvents, making quinoline-2-carboxylic acid more soluble when heated.

To summarize, the solubility of quinoline-2-carboxylic acid is influenced by solvent polarity, pH levels, and temperature, making it a fascinating subject for further study in chemical sciences.

Interesting facts

Interesting Facts About Quinoline-2-Carboxylic Acid

Quinoline-2-carboxylic acid is a fascinating organic compound with numerous applications in various fields of chemistry. Here are some intriguing aspects of this compound:

  • Structure and Derivation: Quinoline-2-carboxylic acid is derived from quinoline, which is a bicyclic compound characterized by its fusion of a benzene ring and a pyridine ring. This unique structure imparts exceptional properties to quinoline derivatives.
  • Biological Significance: Compounds related to quinoline-2-carboxylic acid have been studied for their potential biological activities. Researchers have found derivatives of this compound to possess antibacterial, antiviral, and anti-inflammatory properties, making them of great interest in pharmaceutical research.
  • Role in Synthesis: Quinoline-2-carboxylic acid is a versatile building block in organic synthesis. It serves as a precursor for synthesizing various complex molecules, thus playing a crucial role in the development of new compounds in medicinal chemistry.
  • Research Frontiers: The compound has garnered attention in the field of materials science. Studies reveal its potential application in creating novel materials such as dyes and pigments, owing to its interesting optical properties.
  • Environmental Applications: Quinoline-2-carboxylic acid also finds a place in environmental chemistry. It's explored for its role in soil remediation and as a chelating agent in removing heavy metals from contaminated environments.
  • Historical Context: The exploration of quinoline derivatives dates back to the early 19th century, making them integral to the history of organic chemistry. The study of quinoline-2-carboxylic acid further enriches this narrative, demonstrating the evolution of chemical research.

In conclusion, quinoline-2-carboxylic acid is not just a simple organic compound; it embodies the intersection of various scientific disciplines, showcasing its versatility and significance in modern chemistry.

Synonyms
Quinoline-2-carboxylic acid
QUINALDIC ACID
93-10-7
2-Quinolinecarboxylic acid
Quinaldinic acid
2-Carboxyquinoline
2-Quinolinylcarboxylic acid
Quinolinecarboxylic acid
1199266-78-8
2-Quinoline carboxylic acid
2-Quinolinecarboxylate
MFCD00006752
Chinaldinsaeure
CHEBI:18386
NSC 4882
EINECS 202-218-3
BRN 0126322
P90NWT719R
2-Chinolincarbonsaeure
AI3-18872
Quinoline-2-carboxylic acid anion
NSC-4882
QUINALDIC ACID [MI]
26469-60-3
DTXSID6059079
5-22-03-00183 (Beilstein Handbook Reference)
2-?Quinolinecarboxylic Acid
2-quinaldic acid
chinaldinsaure
UNII-P90NWT719R
Quinaldinate
2Carboxyquinoline
Quinaldic Acid, 2-Carboxyquinoline, 2-Quinolinic Acid, 2-Quinolinylcarboxylic Acid,Quinaldinic Acid, Quinolin-2-carboxylic Acid
2-Quinolinylcarboxylate
Quinolin-2-carboxylate
Quinaldic acid, 98%
quinoline, 2-carboxy-
2quinolinecarboxylic acid
quinoline carboxylic acid
Quinoline2carboxylic acid
quinolinium-2-carboxylate
2Quinolinylcarboxylic acid
quinoline-2-carboxylic acid (quinaldic acid)
bmse000417
Quinolin-2-carboxylic acid
2-quinoline-carboxylic acid
Cambridge id 5116923
Oprea1_469219
Oprea1_509154
SCHEMBL39024
WLN: T66 BNJ CVQ
Chinolin-2-carbonsA currencyure
CHEMBL1160559
DTXCID7048829
NSC4882
HMS1648G18
HMS3604O18
ALBB-005959
BDBM50546252
STK500701
AKOS000119019
AB00802
AC-2457
CS-W002011
DB02428
FQ10003
FS-2156
HY-W002011
SDCCGMLS-0065930.P001
NCGC00330664-01
BP-13045
SY001304
Quinaldic Acid;Quinoline-2-carboxylic acid
DB-023064
NS00015184
Q0003
S6366
EN300-19301
C06325
2,3-pyridinedicarboxylic acid (quinolinic acid)
AB01325078-02
AH-034/32851010
AK-830/25033071
Q17189267
F1018-0303
Z104473458
202-218-3