Skip to main content

Proline

ADVERTISEMENT
Identification
Molecular formula
C5H9NO4
CAS number
609-36-9
IUPAC name
pyrrolidine-2,4-dicarboxylic acid
State
State

Proline is a solid at room temperature, presenting as a crystalline substance. It is stable under normal conditions and is typically used in its solid form for various biochemical applications.

Melting point (Celsius)
200.00
Melting point (Kelvin)
473.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
129.12g/mol
Molar mass
129.1150g/mol
Density
1.4400g/cm3
Appearence

Pyrrolidine-2,4-dicarboxylic acid, commonly known as proline, appears as a white crystalline solid. In its pure form, it is typically encountered as a powder that is white to off-white in appearance.

Comment on solubility

Solubility of Pyrrolidine-2,4-dicarboxylic Acid (C5H9NO4)

Pyrrolidine-2,4-dicarboxylic acid, a five-membered nitrogenous compound, exhibits interesting solubility properties that can often be attributed to its molecular structure and the presence of carboxylic acid functional groups. Here are some key points regarding its solubility:

  • Water Solubility: This compound is typically soluble in water due to the polar carboxylic acid groups that can form hydrogen bonds with water molecules.
  • Solvent Compatibility: Pyrrolidine-2,4-dicarboxylic acid tends to dissolve well in organic solvents such as ethanol and methanol, which suggests its amphiphilic nature.
  • pH Dependency: The solubility of this compound can be influenced by the pH of the solution. In more alkaline conditions, the carboxylic acid groups can deprotonate, enhancing its solubility.
  • Temperature Effects: Like many other organic compounds, increasing the temperature usually results in higher solubility, making it more versatile in various applications.

In summary, the solubility of pyrrolidine-2,4-dicarboxylic acid is significantly influenced by factors such as solvent type, pH, and temperature, making it a compound of interest for various chemical and biological applications.

Interesting facts

Interesting Facts about Pyrrolidine-2,4-Dicarboxylic Acid

Pyrrolidine-2,4-dicarboxylic acid, often referred to in scientific literature, is an intriguing compound that exemplifies the complexity of organic chemistry. Here are some fascinating insights into this molecule:

  • Structure and Functionality: The compound features two carboxylic acid groups attached to a pyrrolidine ring. This unique structure confers valuable properties, making it useful in various chemical reactions and syntheses.
  • Biochemical Relevance: Pyrrolidine-2,4-dicarboxylic acid is a precursor in the synthesis of amino acids and plays an important role in the biochemical pathways of certain organisms. It is particularly noted for its involvement in the metabolism of proline.
  • Potential Applications: Research has shown that this compound may have potential applications in pharmaceuticals and agrochemicals due to its structural uniqueness. Its carboxylic groups can facilitate interactions with biological targets.
  • Stereochemistry: The stereochemistry of pyrrolidine derivatives is a rich field of study. The compound’s ability to exist in multiple configurations can influence its reactivity and interactions, making it a significant subject in stereochemical research.
  • Research Opportunities: Scientists are continually exploring the properties of pyrrolidine-2,4-dicarboxylic acid. Its diverse reactivity provides a fertile ground for producing novel materials and compounds in medicinal chemistry.

In summary, pyrrolidine-2,4-dicarboxylic acid stands out not only for its intriguing molecular structure but also for its practical applications in chemistry and biochemistry. As scientists delve deeper into its properties, we may uncover even more benefits and uses for this fascinating compound.

Synonyms
Pyrrolidine-2,4-dicarboxylic acid
99319-03-6
2,4-Pyrrolidinedicarboxylic acid
Pdc-2,4
Pyrrolidine-2,4-dicarboxylate
1-trans-Pyrrolidine-2,4-dicarboxylic acid
L-trans-Pyrrolidine-2,4-dicarboxylic acid
DTXSID10912746
1-pyrrolidine-2,4-dicarboxylic acid
2,4-pyrrolidine dicarboxylate
188345-76-8
L-pyrrolidine-2,4-dicarboxylic acid
l-trans-2,4-pyrrolidine dicarboxylate
rel-(2S,4S)-Pyrrolidine-2,4-dicarboxylic acid
SCHEMBL542244
DTXCID00866800
AT43372
PB48186