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Niacin

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Identification
Molecular formula
C6H5NO2
CAS number
59-67-6
IUPAC name
pyridine-3-carboxylate
State
State

At room temperature, niacin is a solid that can exist in the form of crystalline powder.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
123.11g/mol
Molar mass
123.1110g/mol
Density
1.4730g/cm3
Appearence

Niacin appears as a white crystalline solid or fine powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of Pyridine-3-carboxylate (C6H5NO2)

Pyridine-3-carboxylate, with its distinctive chemical structure, exhibits notable solubility characteristics that are fascinating to explore. This compound is generally soluble in polar solvents, making it suitable for various applications in chemical synthesis and industrial processes. Here are some key points regarding its solubility:

  • Polar Solvents: Pyridine-3-carboxylate tends to dissolve well in water and alcohols due to its polar carboxylate group.
  • Hydrogen Bonding: The presence of the carboxylate moiety facilitates hydrogen bonding with solvents, enhancing its solubility.
  • Temperature Dependence: Its solubility may increase with temperature, a common trend observed in many organic compounds.
  • Non-Polar Solvents: Conversely, it has limited solubility in non-polar solvents given its polar nature, which can hinder interaction with such environments.

In summary, the solubility profile of pyridine-3-carboxylate underscores its versatility and relevance in various chemical contexts. The compound's ability to engage with different solvent systems illustrates the importance of understanding solubility principles in chemical research and application.

Interesting facts

Interesting Facts about Pyridine-3-Carboxylate

Pyridine-3-carboxylate, also known in some contexts as 3-pyridinecarboxylate, is a fascinating compound that belongs to the family of pyridine derivatives. Its distinct structure and properties make it a subject of interest in various fields, such as organic chemistry, biochemistry, and pharmaceuticals.

Chemical Characteristics

  • Functional Group: Pyridine-3-carboxylate features a carboxylate group, which is essential for its reactivity and interaction with other substances.
  • Isomer Relevance: This compound is one of several isomers of carboxylate derivatives of pyridine, each exhibiting different chemical behavior.

Applications in Science and Industry

  • Pharmaceuticals: Pyridine derivatives, including pyridine-3-carboxylate, are significant in drug design. They often serve as building blocks for more complex medicinal compounds.
  • Biological Relevance: This compound can act as a biochemical precursor, involved in metabolic pathways essential for various biological functions.

Notable Reactions

Pyridine-3-carboxylate can participate in various chemical reactions, such as:

  • Electrophilic substitution reactions due to the presence of the electron-withdrawing carboxyl group.
  • Decarboxylation, a reaction where the carboxyl group is removed, generating a simpler pyridine compound.

Educational Perspective

For students, understanding pyridine-3-carboxylate can enhance one's grasp of:

  • The importance of functional groups in determining the properties and reactivity of organic molecules.
  • How molecular structure influences biological activity and interaction within living systems.

In the words of a chemist, "The beauty of chemistry lies in understanding how simple structures create complex behaviors." Thus, pyridine-3-carboxylate serves as an excellent representation of this concept.

Synonyms
nicotinate
pyridine-3-carboxylate
3-pyridinecarboxylate
3 Pyridinecarboxylic Acid
nico-400-
CHEBI:32544
PVNIIMVLHYAWGP-UHFFFAOYSA-M
AC-907/25004509
AE-848/01496050
Q27104221