Interesting facts
Exploring Pyridine-3-Carboxamide
Pyridine-3-carboxamide, often referred to as nicotinamide or niacinamide, is a fascinating compound belonging to the family of pyridines. As an aromatic heterocyclic compound, it displays a unique structure that contributes to its diverse range of applications in various fields:
- Pharmaceuticals: Prominently utilized in the healthcare industry, pyridine-3-carboxamide plays a critical role in skin care formulations and has been shown to possess anti-inflammatory properties.
- Biochemistry: This compound is an essential precursor of nicotinamide adenine dinucleotide (NAD), a crucial coenzyme involved in metabolic processes, including cellular energy production.
- Research Applications: Scientists often leverage pyridine-3-carboxamide in research for studying cell signaling pathways and gene expression.
In terms of its mechanism, pyridine-3-carboxamide is known for its ability to:
- Enhance skin hydration by preventing moisture loss.
- Minimize the appearance of fine lines and pigmentation.
- Exhibit antioxidant properties, protecting the skin from oxidative stress.
One compelling aspect of pyridine-3-carboxamide is its dual role in both nutrition and medication. As an integral component of the vitamin B3 group, it is essential for human health. According to research, just 2-3 mg is sufficient for maintaining optimal health, with higher doses prescribed for specific conditions.
Furthermore, the potential neuroprotective effects of pyridine-3-carboxamide are being explored as a therapeutic avenue for neurodegenerative diseases, highlighting its promise in pharmaceutical development.
In summary, pyridine-3-carboxamide is a compound that underscores the intersection of chemistry and health, embodying a rich profile of benefits that extend beyond simple biochemical roles, making it a valuable subject of study and application.
Synonyms
nicotinamide
niacinamide
98-92-0
3-Pyridinecarboxamide
pyridine-3-carboxamide
Nicotinic acid amide
vitamin PP
Aminicotin
Amixicotyn
Papulex
Nicotylamide
Endobion
Hansamid
Nicobion
Nikotinamid
Savacotyl
Benicot
Dipegyl
Pelmine
Nicotinic amide
Delonin amide
Pelonin amide
Austrovit PP
Vi-Nicotyl
Inovitan PP
Amnicotin
Nicamindon
Nicomidol
Nicosylamide
Nicotamide
Nicotilamide
Nicotililamido
Nicovitina
Nicovitol
Nicozymin
Niocinamide
Niacevit
Niamide
Nicamina
Nicasir
Nicofort
Nicogen
Nicotol
Nicovit
Niozymin
Nicota
Niko-tamin
3-Carbamoylpyridine
Nandervit-N
Nicotinamidum
Niavit PP
Nicosan 2
Nicotine amide
Nicotine acid amide
Nikotinsaeureamid
Pyridine-3-carboxylic acid amide
Vitamin B
Pyridine, 3-carbamoyl-
Nicotylamidum
Nicotinsaureamid
beta-Pyridinecarboxamide
Nicotinamida
Mediatric
Factor pp
m-(Aminocarbonyl)pyridine
3-Pyridinecarboxylic acid amide
Pelmin
Acid amide
Witamina PP
PP-Faktor
Amid kyseliny nikotinove
Amide PP
3-(aminocarbonyl)pyridine
Dipigyl
Niacinamid
Nicovel
Vitamin B (VAN)
CCRIS 1901
Nicotinsaureamid [German]
NAM
HSDB 1237
Nikotinsaeureamid [German]
Amid kyseliny nikotinove [Czech]
Nicotinamidum [INN-Latin]
Nicotinamida [INN-Spanish]
AI3-02906
NSC 13128
Nicotinamid
Nictoamide
Nicotinsaeureamid
3-Amidopyridine
Vi-noctyl
EINECS 202-713-4
MFCD00006395
NSC-13128
NSC-27452
b-Pyridinecarboxamide
Niacinamide (USP)
Niacinamide [USP]
UNII-25X51I8RD4
Nicotinamide [INN]
DTXSID2020929
CHEBI:17154
25X51I8RD4
Nicotinamide (Standard)
NSC13128
.beta.-Pyridinecarboxamide
Nicotinamide (Vitamin B3)
CHEMBL1140
DTXCID00929
MLS000069714
TPN COMPONENT NIACINAMIDE
EC 202-713-4
NSC27452
NCGC00093354-03
NCGC00093354-05
SMR000058212
Nicotinamide 10 microg/mL in Acetonitrile
NIACINAMIDE (II)
NIACINAMIDE [II]
Niacinamide;Nicotinic acid amide;Vitamin B3
WLN: T6NJ CVZ
Nicotinamidum (INN-Latin)
Nicotinamida (INN-Spanish)
NIACINAMIDE (USP-RS)
NIACINAMIDE [USP-RS]
NICOTINAMIDE (MART.)
NICOTINAMIDE [MART.]
Nicotinamide-(amide-15N)
3 Pyridinecarboxamide
Niacinamide [USAN]
NICOTINAMIDE (EP IMPURITY)
NICOTINAMIDE [EP IMPURITY]
NIACINAMIDE (USP MONOGRAPH)
NIACINAMIDE [USP MONOGRAPH]
NICOTINAMIDE (EP MONOGRAPH)
NICOTINAMIDE [EP MONOGRAPH]
CAS-98-92-0
Vitamin B3;Nicotinamide;3-Pyridinecarboxamide
SR-01000721872
Niacotinamide
Nicosedine
Nicamid
nicotin-amide
Pahaba Control
Ultra Whitening
CellExosome HR
CellExosome SB
DEA No. 1405
Celonia CM
Ginseng Whitening
Dr. Cellmo
Royal GinsengCream
TOAS Rejuvenation
Nicotinamide,(S)
Vitamin B3 amide
Costem cell 5 N
Royal GinsengLotion
AAPE Skin Ampoule
CellExosome HE HR
Fantastic LightCream
Royal Ginseng Toner
Vita C Bright Serum
Vita C Bright Toner
Niacinamide Face Mask
Royal Ginseng Essence
Ultra Whitening Ample
11032-50-1
TANIA PURECREAM
JUVEHEAL W Ampoule
Nicotinamidum (Latin)
BREXTEM S
NI-NICOTYL
Mediatric (Salt/Mix)
niacin - Vitamin B3
Dr. Color Effect Red
1yc5
DPC Aura Booster Mask
Dr Cellinme Mask Sheet
Opera_ID_775
Vita C Bright EyeCream
Miracle Laser Skin Mist
Niacin (as niacinamide)
Pyridine-3-carboxylamide
APLIN SPOT REMOVER
KARATICA I M CURE
NIACINAMIDE [FCC]
NICOTINAMIDE [MI]
TANIA PURE ESSENCE
VITA C BRIGHTCREAM
Pellagra-Preventing Factor
INTOMEDI HR PEPTIDE
NIACINAMIDE [HSDB]
NICOTINAMIDE [JAN]
NYAAM NYAAM Vita Serum
RGO HYDRATION TONER
bmse000281
Miracle Moisturizer Essence
MolMap_000061
APLIN SPOT ALL KILL
MOISTIE PURE ESSENCE
NIACINAMIDE [VANDF]
DPC Whitening Booster Mask
SCHEMBL2926
AAPE Nutrient Facial Toner
Nicotinamide (JP17/INN)
NICOTINAMIDUM [HPUS]
NYAAM NYAAM Peptide Serum
Cellpium double essence toner
AAPE Continuous Renewal Mask
MLS001424246
Primerose Snail Hydro Essence
Shieldlife Whitening Ion Mask
Ultra V AQUA SHINE MASK
Ultra Whitening First Essence
NICOTINAMIDE [WHO-DD]
NICOTINAMIDE [WHO-IP]
by selected hyaluron day serum
Dr Cellinme Skin Care Ampoule
CELLPIUM REAL MASK PACK
Cellpium super richness ampoule
CAVIALL Wrinkle-Free PowerTox
Cellpium premiumEX hybrid toner
Revital Perfecting Dual Ampoule
SCHEMBL6278767
SGCUT00176
Daily Whitening Care Sheet Mask
Edge Cutimal Cat Whitening Mask
SCHEMBL19978192
BDBM27507
CELLBN MILKY TONE-UPCREAM
HY-B0150R
Nicotinamide - Bio-X trade mark
NYAAM NYAAM Skin Reborn Serum
A11HA01
Cellpium premiumEX hybrid essence
NIACINAMIDE [ORANGE BOOK]
BRIGHTUNING PEPTIDE AMPOULE
Nicotinamide, niacin, vitamin B3
HMS2052M21
HMS2090B05
HMS2093H03
HMS2236J03
HMS3370F21
HMS3394M21
HMS3655M20
HMS3713B22
HMS3884A16
Pharmakon1600-01505397
Ala-C Snail Cell Reparing Essence
AROCELL TIME REVERSE K I T
DR. GLODERM TABRX WHITENING
BCP07322
COSMEPURE BRIGHTENING CALMING
HY-B0150
NIACINAMIDE COMPONENT OF TPN
THE SKIN HOUSE Vital BrightCream
THE SKIN HOUSE Vital BrightSerum
to_000073
ARILAC Brightening Mask Sheet Pack
Nicotinamide 1.0 mg/ml in Methanol
Nicotinamide, >=98.5% (HPLC)
Nicotinamide, >=99.5% (HPLC)
Tox21_111202
Tox21_201716
Tox21_302776
NICOTINAMIDUM [WHO-IP LATIN]
NSC759115
s1899
STL163867
THE SKIN HOUSE Vital Bright Toner
SFERANGS VITA C CAPSULEBOOSTER
AKOS005715850
Niveola P.H.c 3d Festival Mask Pack
Skin Project Ya Cooling Celluven Mask
THE SKIN HOUSE Vital BrightEmulsion
Tox21_111202_1
CCG-101149
CS-1968
DB02701
FN01411
NC00399
NSC-759115
SB74497
Bk Cell 5days Of Secret Snow Whitening
EVECODE THREAD LIFTING MASK PACK
Nicotinamide 100 microg/mL in Methanol
Nicotinamide, >=98% (HPLC), powder
THE SKIN HOUSE Vital Bright Emulsion
THE SKIN HOUSE Vital Bright EyeCream
NCGC00093354-04
NCGC00093354-06
NCGC00093354-09
NCGC00256432-01
NCGC00259265-01
NIACIN (AS NIACINAMIDE) [VANDF]
AS-13845
BN166252
BN183763
COSMEPURE BRIGHTENING CALMING TONER
DERLADIE HerbalExtract BodySolution MIST
Nicotinamide, puriss., 99.0-101.0%
SY024804
DR. GLODERM TIME TO WHITENING MASK
FRESH MANDARIN AROMATHERAPY MASK27g
SBI-0206826.P001
AN ADC SP INTENSIVE MOISTURE ESSENCE
DB-057754
CS-0694823
Derma Pella Facial Cleanser for Normal Skin
DR.ALTHEA POWER WHITENING GLUTATHIONE
MIZON ENJOY VITAL UP TIME Whitening Mask
N0078
NS00005364
SW197779-3
The Hayan Cherry Blossom Brightening Essence
EN300-15612
Niacinamide, meets USP testing specifications
C00153
D00036
DERMAHAN THE WHITENING MOISTURIZING MASK
Nicotinamide (Niacinamide), analytical standard
AB00373895-13
AB00373895_15
AB00373895_16
Derma Pella Cleanser for Sensitive and Dry Skin
Nicotinamide, Vetec(TM) reagent grade, >=98%
A845925
AC-907/25014114
AG-227/20370056
AROCELL X BELLE J SUPER POWER CELL AMPOULE
J9 ULTRA ADVANCED INTENSIVE SCALP SERUM V2
Q192423
LEBODY LAB RENEWAL DUAL EFFECT PEPTIDE SERUM
SR-01000721872-3
SR-01000721872-4
SR-01000721872-5
BRD-K28912512-001-23-2
BRD-K28912512-001-24-0
BRD-K28912512-001-25-7
LEBODY LAB RENEWAL DUAL EFFECT IDEBENONE SERUM
MUSTUS DAILY HARVEST SQUEEZE TONE UP MASK PACK
PAPA RECIPE BOMBEE BRIGHTENING HONEY MASK PACK
SISEUNDEUSI LUMINANT MASK PACK STEP2(WHITENING)
Z33546463
F2173-0513
Niacinamide;Nicotinic acid amide;Vitamin B3; Vitamin PP
Nicotinamide, British Pharmacopoeia (BP) Reference Standard
A186B02E-6C70-4E54-9739-79398D439AAA
Nicotinamide, European Pharmacopoeia (EP) Reference Standard
Niacinamide, United States Pharmacopeia (USP) Reference Standard
InChI=1/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9
Niacinamide, Pharmaceutical Secondary Standard; Certified Reference Material
Nicotinamide, BioReagent, suitable for cell culture, suitable for insect cell culture
202-713-4
Solubility of Pyridine-3-carboxamide
Pyridine-3-carboxamide, with the chemical formula C6H6N2O, exhibits interesting solubility characteristics that are influenced by its molecular structure.
Water Solubility
This compound is generally considered to be moderately soluble in water. This solubility can be attributed to the presence of the carboxamide functional group, which can form hydrogen bonds with water molecules.
Solvent Compatibility
In addition to water, pyridine-3-carboxamide is known to be soluble in various organic solvents, enhancing its versatility in chemical applications. The following are notable aspects of its solubility:
Factors Influencing Solubility
Several factors influence the solubility of pyridine-3-carboxamide:
In summary, the solubility of pyridine-3-carboxamide is a product of its functional groups and the solvents involved. Understanding these solubility dynamics is essential for its effective application in various chemical contexts.