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3-Cyanopyridine

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Identification
Molecular formula
C6H4N2
CAS number
100-48-1
IUPAC name
pyridine-3-carbonitrile
State
State

At room temperature, 3-Cyanopyridine is generally found as a solid. It has a low melting point, which allows it to become liquid with slight heating.

Melting point (Celsius)
52.00
Melting point (Kelvin)
325.15
Boiling point (Celsius)
211.00
Boiling point (Kelvin)
484.15
General information
Molecular weight
104.12g/mol
Molar mass
104.1170g/mol
Density
1.1165g/cm3
Appearence

3-Cyanopyridine is typically a solid compound that appears as colorless crystallites or powder. However, it can also appear as a clear liquid if it is melted. The powdered form may sometimes have a slight yellowish tint due to impurities or exposure to air.

Comment on solubility

Solubility of Pyridine-3-carbonitrile (C6H4N2)

Pyridine-3-carbonitrile, known for its unique heterocyclic structure, showcases interesting solubility characteristics:

  • Solvent Compatibility: Pyridine-3-carbonitrile is typically soluble in polar organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO).
  • Water Solubility: This compound has limited solubility in water, indicating that it favors more lipophilic environments.
  • Influence of Functional Groups: The presence of the cyano group (-C≡N) influences its polar character, affecting how it interacts with various solvents.
  • Temperature Dependence: Like many organic compounds, its solubility may increase with temperature, which is a crucial factor when considering its applications.

In summary, the solubility profile of pyridine-3-carbonitrile reflects its chemical nature and functional groups, making it more compatible with specific organic solvents while remaining relatively insoluble in water.

Interesting facts

Interesting Facts about Pyridine-3-carbonitrile

Pyridine-3-carbonitrile, also known as 3-cyanopyridine, is an intriguing compound that has garnered significant interest in the field of organic chemistry. Here are some compelling facts about this unique heterocyclic compound:

  • Reactivity and Applications: Pyridine-3-carbonitrile is a versatile building block in organic synthesis. Its functional groups enable a range of chemical reactions, making it useful in the production of pharmaceuticals and agrochemicals.
  • Biological Activity: Many derivatives of pyridine-3-carbonitrile exhibit remarkable biological properties, including antimicrobial and anti-inflammatory effects. Research is ongoing to explore its potential as a therapeutic agent.
  • Industrial Importance: This compound serves as an intermediate in the manufacture of compounds like pyridine and other nitrogen-containing heterocycles, which are vital in the dye and chemical industry.
  • Research Utility: Pyridine-3-carbonitrile is often used in studies related to material science and catalysis, showcasing its role in the development of new synthetic methodologies.
  • Environmental Impact: As a nitrogen-containing aromatic compound, understanding its behavior in the environment is crucial for evaluating its ecological effects and persistence.

In summary, pyridine-3-carbonitrile is more than just a simple carbonitrile; it is a compound with a broad spectrum of applications and ongoing research opportunities. Its unique structure and reactivity continue to make it a subject of interest within the scientific community.

Synonyms
3-cyanopyridine
Nicotinonitrile
100-54-9
3-PYRIDINECARBONITRILE
pyridine-3-carbonitrile
Nicotinic acid nitrile
3-Pyridinenitrile
3-Pyridylcarbonitrile
3-Azabenzonitrile
3-Cyjanopirydyna
Nitryl kwasu nikotynowego
3-Cyjanopirydyna [Polish]
NSC 17558
HSDB 5335
3-Pyridinecarboxylic acid, nitrile
Nitryl kwasu nikotynowego [Polish]
EINECS 202-863-0
BRN 0107711
Pyridine, 3-cyano-
DTXSID1026665
CHEBI:86556
AI3-15766
MFCD00006372
NSC-17558
X64V0K6260
DTXCID606665
EC 202-863-0
5-22-02-00115 (Beilstein Handbook Reference)
3-PYRIDINECARBONITRILE [HSDB]
CAS-100-54-9
3Cyjanopirydyna
3Azabenzonitrile
3Pyridinenitrile
UNII-X64V0K6260
3-cyano pyridine
3-Pyridyl cyanide
3Pyridinecarbonitrile
PncA Inhibitor, 5
bmse000622
CYANOPYRIDINE, 3-
SCHEMBL28776
Nicotinamidase Inhibitor, 23
3-Pyridinecarbonitrile, 98%
CHEMBL3181972
BDBM92856
3Pyridinecarboxylic acid, nitrile
NSC17558
Tox21_201669
Tox21_300354
BBL037217
STK046164
AKOS000119616
3-Pyridinecarbonitrile; Nicotinonitrile
AC-2424
FG-0468
SB52234
NCGC00248004-01
NCGC00248004-02
NCGC00254450-01
NCGC00259218-01
DB-023674
CS-0003918
NS00008250
EN300-18318
P19604
AC-907/25014098
Q18730591
Z57899719
F2108-0102
6C16C9E3-90DC-4565-9F55-F6CC5D13CC33
202-863-0