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nicotinaldehyde oxime

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Identification
Molecular formula
C6H6N2O
CAS number
1003-82-5
IUPAC name
pyridine-3-carbaldehyde oxime
State
State

At room temperature, pyridine-3-carbaldehyde oxime is typically found as a solid. Its crystalline structure can absorb moisture from the environment, though it largely remains a stable solid under standard conditions. It can also be dissolved in organic solvents for various chemical applications.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
268.40
Boiling point (Kelvin)
541.55
General information
Molecular weight
122.13g/mol
Molar mass
122.1250g/mol
Density
1.1113g/cm3
Appearence

Pyridine-3-carbaldehyde oxime typically appears as a fine crystalline solid. The color can vary from colorless to slightly yellow, depending on the purity and specific conditions of storage. It may also present a distinct odor characteristic of pyridine derivatives, slightly resembling an aromatic solvent smell. The compound is commonly used in chemical synthesis and may demonstrate different properties when incorporated into complexes or under various conditions.

Comment on solubility

Solubility of Pyridine-3-carbaldehyde Oxime

Pyridine-3-carbaldehyde oxime, with the chemical formula C6H6N2O, exhibits interesting solubility characteristics that can be advantageous in various applications:

  • Polar Character: The presence of the oxime functional group (-C=N-OH) contributes to its polar character, making it soluble in polar solvents.
  • Solvent Compatibility: Pyridine-3-carbaldehyde oxime is typically soluble in water and alcohols, as well as other polar organic solvents.
  • Insolubility in Nonpolar Solvents: Due to its polar nature, it shows poor solubility in nonpolar solvents like hexane or benzene.

Overall, the solubility profile of pyridine-3-carbaldehyde oxime enables its use in various chemical reactions and as a building block in synthetic organic chemistry. As encapsulated in the quote, "Solubility is the key to reactivity," understanding its solubility can lead to improved application outcomes in research and industrial processes.

Interesting facts

Interesting Facts about Pyridine-3-carbaldehyde Oxime

Pyridine-3-carbaldehyde oxime is a fascinating compound with a distinct chemical structure and a variety of applications in the field of chemistry. Here are some notable aspects:

  • Structure and Isomerism: The compound features a pyridine ring, which is a six-membered aromatic ring containing one nitrogen atom. This unique structure allows for several isomeric forms, which can lead to different chemical behaviors.
  • Reactivity: As an oxime, this compound can engage in a variety of reactions, including condensation, which is important in syntheses involving carbon-nitrogen bond formation. This makes it a valuable building block for chemists.
  • Applications: Pyridine-3-carbaldehyde oxime plays a significant role in the synthesis of various pharmaceuticals and agrochemicals. It is particularly noted for its utility in developing compounds with potential biological activities.
  • Biological Significance: Compounds derived from pyridine bases are often found to exhibit interesting biological properties, including antimicrobial and anti-inflammatory activities, making the study of pyridine derivatives crucial in medicinal chemistry.
  • Historical Importance: Pyridine itself was first obtained from coal tar in the 19th century, which paved the way for further research into its derivatives and their reactions, laying the groundwork for modern organic synthesis techniques.

In summary, pyridine-3-carbaldehyde oxime offers intriguing avenues for exploration in both synthetic chemistry and medicinal applications. As chemists continue to investigate its properties and potential uses, it remains an exciting compound in the realm of chemical research.

Synonyms
3-pyridine aldoxime
1193-92-6
3-formylpyridine oxime
pyridine-3-carbaldehyde oxime
CHEBI:86555
N-[(pyridin-3-yl)methylidene]hydroxylamine
N-(pyridin-3-ylmethylidene)hydroxylamine
3-Pyridinecarbaldehyde oxime
DTXSID30922928
YBKOPFQCLSPTPV-UHFFFAOYSA-N
ALBB-019926
AKOS000266539
AKOS015935086
DB-041469