Interesting facts
Exploring Pyridin-4-amine
Pyridin-4-amine, also known as 4-aminopyridine, is a fascinating organic compound that belongs to the family of pyridine derivatives. This heterocyclic compound has garnered significant interest in the field of chemistry and pharmacology due to its diverse applications. Here are some intriguing facts about pyridin-4-amine:
- Pharmaceutical Relevance: Pyridin-4-amine plays a crucial role in medicinal chemistry. It has been investigated for its potential in treating neurological disorders such as multiple sclerosis and spinal cord injuries. The compound works by enhancing nerve conduction, making it a subject of ongoing research.
- Agonistic Activity: This compound acts as a potassium channel blocker. By inhibiting potassium ion channels, pyridin-4-amine can influence neurotransmitter release, ultimately affecting synaptic transmission.
- Synthetic Versatility: The chemical structure of pyridin-4-amine allows for a variety of synthetic modifications, enabling chemists to create a range of derivatives. This versatility is beneficial for designing new pharmaceuticals with enhanced efficacy and reduced side effects.
- Analytical Applications: Due to its unique properties, pyridin-4-amine is employed in analytical chemistry as a reagent. It can assist in the detection and quantification of various substances in complex mixtures.
To quote the famous chemist Linus Pauling, “The best way to have a good idea is to have a lot of ideas.” Pyridin-4-amine is an embodiment of this principle, showcasing the continuous innovation within chemical research and its potential impact on modern medicine.
In summary, pyridin-4-amine not only exemplifies the intricate designs of organic chemistry but also stands as a testament to the blend of science and medicine, offering hope for treating challenging conditions. With ongoing research, the future of this compound looks promising!
Synonyms
4-aminopyridine
504-24-5
pyridin-4-amine
Fampridine
4-Pyridinamine
Dalfampridine
4-Pyridylamine
p-Aminopyridine
4-AP
Avitrol
Ampyra
gamma-Aminopyridine
Pyridine, 4-amino-
FAMPYRA
Compound 1861
Pimadin (free base)
Amino-4 pyridine
Neurelan
Amaya
Avitrol 200
Phillips 1861
4 Aminopyridine
Prc 1237
fampridina
Caswell No. 038
EL-970
VMI 10-3
fampridinum
NSC 15041
C5H6N2
HSDB 6037
UNII-BH3B64OKL9
pyridin-4-ylamine
EINECS 207-987-9
BH3B64OKL9
NSC-15041
Fampridine [INN]
BIIB041
EPA Pesticide Chemical Code 069201
BRN 0105782
BIIB 041
.gamma.-Aminopyridine
DTXSID0023870
CHEBI:34385
Dalfampridine [USAN]
AI3-52547
N07XX07
Fampridine (4-aminopyridine)
MLS000069400
CHEMBL284348
DTXCID003870
Dalfampridine (4-aminopyridine)
5-22-09-00106 (Beilstein Handbook Reference)
NSC15041
MFCD00006439
Dalfampridine (USAN)
NCGC00015009-08
Pymadine
SMR000058211
286367-79-1
Fampridine-SR
DALFAMPRIDINE (II)
DALFAMPRIDINE [II]
FAMPRIDINE (MART.)
FAMPRIDINE [MART.]
DALFAMPRIDINE (USP-RS)
DALFAMPRIDINE [USP-RS]
ACETYL-2-13C CHLORIDE,2,2-DICHLORO- (9CI)
VMI-103
DALFAMPRIDINE (USP MONOGRAPH)
DALFAMPRIDINE [USP MONOGRAPH]
4-amino pyridine
4-amino-pyridine
4- Aminopyridine
Mi-W-3
4AP
CAS-504-24-5
Ampyra (TN)
VMI 103
SR-01000075299
RCRA waste no. P008
Dalfampridine [USAN:INN]
Frampridine
Ampydin
Pymadin
Fampridine-PR
Dalfampridine-ER
4-pyridyl amine
para-aminopyridine
pyridine-4-amine
3rxf
Neurelan (TN)
pyridine-4-ylamine
Fampyra (TN)
pyridin-4-yl-amine
4-Aminopyridine 10
Philips 1861
4-AMINOPYRDINE
Spectrum_000155
Tocris-0940
Fampridine (JAN/INN)
4-Aminopyridine, 98%
FAMPRIDINE [JAN]
PYRIDINE,4-AMINO
Opera_ID_1768
Spectrum2_001413
Spectrum3_000914
Spectrum4_001013
Spectrum5_001501
4-Pyridinamine;Fampridine
Lopac-A-0152
DALFAMPRIDINE [MI]
FAMPRIDINE [VANDF]
UPCMLD-DP125
WLN: T6NJ DZ
4-Aminopyridine (4-AP)
4-Aminopyridine, >=99%
DALFAMPRIDINE [HSDB]
FAMPRIDINE [WHO-DD]
1,4-dihydropyridin-4-imine
Lopac0_000032
BSPBio_001562
DALFAMPRIDINE [VANDF]
KBioGR_000282
KBioGR_001505
KBioSS_000282
KBioSS_000635
DivK1c_000572
FAMPRIDINE [EMA EPAR]
SPECTRUM1501130
SPBio_001486
4 AP
BIIB-041
GTPL2416
CL-COB-III-274-1
UPCMLD-DP125:001
BDBM10458
HMS501M14
KBio1_000572
KBio2_000282
KBio2_000635
KBio2_002850
KBio2_003203
KBio2_005418
KBio2_005771
KBio3_000563
KBio3_000564
KBio3_001888
NINDS_000572
Bio1_000353
Bio1_000842
Bio1_001331
Bio2_000282
Bio2_000762
HMS1361O04
HMS1791O04
HMS1921H15
HMS1989O04
HMS2092F05
HMS2234N24
HMS3260G05
HMS3267E21
HMS3370J03
HMS3402O04
HMS3414H15
HMS3678H13
HMS3886I09
KUC111877N
Pharmakon1600-01501130
DALFAMPRIDINE [ORANGE BOOK]
HY-B0604
VMI-10-3
Tox21_110065
Tox21_200793
Tox21_500032
CCG-39031
HB1073
NSC757845
RB8003
s5028
STK298717
AKOS000119896
Tox21_110065_1
BS-3729
DB06637
FA00151
LP00032
NSC-757845
SDCCGMLS-0066228.P001
SDCCGSBI-0050021.P004
IDI1_000572
IDI1_034032
p-Aminopyridine [UN2671] [Poison]
USEPA/OPP Pesticide Code: 069201
NCGC00015009-01
NCGC00015009-02
NCGC00015009-03
NCGC00015009-04
NCGC00015009-05
NCGC00015009-06
NCGC00015009-07
NCGC00015009-09
NCGC00015009-10
NCGC00015009-11
NCGC00015009-12
NCGC00015009-13
NCGC00015009-14
NCGC00015009-16
NCGC00015009-23
NCGC00015009-24
NCGC00024890-01
NCGC00024890-02
NCGC00024890-03
NCGC00024890-04
NCGC00024890-05
NCGC00024890-06
NCGC00024890-07
NCGC00024890-08
NCGC00024890-09
NCGC00024890-10
NCGC00258347-01
NCGC00260717-01
BP-21343
SBI-0050021.P003
DB-028705
A0414
EU-0100032
NS00002207
EN300-21310
FAMPRIDINE (4-AMINOPYRIDINE) [VANDF]
A 0152
D04127
AB00052209_12
[J.Pharmacol.Exp.Ther. 275:864 (1995)]
AC-907/25014071
Q372539
4-Aminopyridine, PESTANAL(R), analytical standard
SR-01000075299-1
SR-01000075299-3
SR-01000075299-5
BRD-K22482860-001-20-6
BRD-K22482860-001-21-4
F2190-0487
Z104495272
Dalfampridine, United States Pharmacopeia (USP) Reference Standard
InChI=1/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7
207-987-9
Solubility of Pyridin-4-amine (C5H6N2)
Pyridin-4-amine, a heterocyclic amine, showcases interesting solubility characteristics that are largely influenced by its molecular structure. Solubility is a crucial property that determines how this compound behaves in various solvents, particularly in laboratory and industrial applications.
General Solubility Behavior
Practical Implications
Understanding the solubility of pyridin-4-amine is essential for its effective application in synthetic chemistry and pharmaceuticals. As noted, its solubility profile enriches its versatility:
In summary, while pyridin-4-amine exhibits good solubility in polar solvents, its performance in non-polar environments can be limited. Thus, selecting the appropriate solvent is critical for maximizing its effectiveness in practical scenarios.