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Pyrazinecarboxamide

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Identification
Molecular formula
C5H6N2O
CAS number
98-96-4
IUPAC name
pyrazine-2-carboxamide
State
State

At room temperature, Pyrazinecarboxamide exists as a solid. It is stable under normal conditions and dissolves in polar organic solvents.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
173.00
Boiling point (Kelvin)
446.15
General information
Molecular weight
122.12g/mol
Molar mass
122.1170g/mol
Density
1.4031g/cm3
Appearence

Pyrazinecarboxamide typically appears as a white or off-white crystalline solid. It is an odorless compound, often characterized by its flat aromatic ring structure.

Comment on solubility

Solubility of Pyrazine-2-carboxamide

Pyrazine-2-carboxamide (C5H6N2O) exhibits interesting solubility characteristics that are influenced by its molecular structure. Here are some key points regarding its solubility:

  • Polarity: The presence of the amide functional group contributes to **moderate polarity**, making it more likely to dissolve in polar solvents.
  • Common Solvents: Pyrazine-2-carboxamide is generally soluble in water due to its ability to form hydrogen bonds with water molecules.
  • Solvent Compatibility: In addition to water, this compound tends to be soluble in a range of organic solvents including ethanol and dimethyl sulfoxide (DMSO).
  • Crystal Form: Depending on the crystalline form, the solubility can vary significantly, which is essential to consider in applications.

Overall, while pyrazine-2-carboxamide’s solubility profiles indicate good compatibility with polar solvents, the **exact solubility can be contingent on environmental factors** such as temperature and pH. Understanding these properties can be crucial in various chemical applications and synthesis processes.

Interesting facts

Interesting Facts about Pyrazine-2-carboxamide

Pyrazine-2-carboxamide is a fascinating compound that plays an essential role in both organic chemistry and material science. As a derivative of pyrazine, this compound brings intriguing properties and potential applications:

  • Biological Relevance: Pyrazine derivatives are often studied due to their biological activity. Pyrazine-2-carboxamide, in particular, has been investigated for its potential pharmacological effects, making it a compound of interest in medicinal chemistry.
  • Versatility: This compound serves as a building block for synthesizing a variety of other pyrazine-based molecules, expanding its usefulness in chemical research and applications.
  • Research Applications: Scientists explore pyrazine-2-carboxamide in the fields of agrochemicals and pharmaceuticals, where its structural features can influence biological activity.
  • Electronic Properties: The unique electronic structure of pyrazine-2-carboxamide can be utilized in organic electronics, particularly in the development of materials for semiconductors and organic light-emitting diodes (OLEDs).
  • Potential in Material Science: Given its chemical characteristics, this compound might find its way into the development of new materials with specific functionalities, such as sensors or catalysts.

In summary, pyrazine-2-carboxamide exemplifies how a simple compound can have a wide range of applications and relevance across various fields of study. As researchers continue to explore its properties, the future holds promising possibilities for this compound.

Synonyms
pyrazinamide
pyrazinecarboxamide
98-96-4
pyrazine-2-carboxamide
Zinamide
Aldinamide
pyrazinoic acid amide
2-Pyrazinecarboxamide
Aldinamid
Pirazinamid
Tebrazid
Unipyranamide
Eprazin
Farmizina
Novamid
Pirazimida
Pyrafat
pyrazine carboxylamide
Pyrazineamide
2-Carbamylpyrazine
Isopas
Pyrazinecarboxylic acid amide
Pirazinamida
Pyrazinamidum
Pyrazide
Rozide
Pirazinamide
Pezetamid
Piraldina
Pyrazine carboxamide
D-50
pyramizade
MK 56
PZA
Rifafour
NCI-C01785
Pyrazinamidum [INN-Latin]
Pirazinamida [INN-Spanish]
Rifafour e-200
DRG 0124
CCRIS 545
MFCD00006132
NSC 14911
pyrazinamida
Pyrizinamide
HSDB 3576
UNII-2KNI5N06TI
EINECS 202-717-6
2KNI5N06TI
NSC-14911
.alpha.-pyrazinamide
BRN 0112306
DTXSID9021215
CHEBI:45285
MK-56
T 165
NSC14911
Pyrazinamide (Pyrazinoic acid amide)
Tisamid
MLS000069730
DTXCID801215
Pyrazinamide [USP:INN:BAN:JAN]
5-25-04-00178 (Beilstein Handbook Reference)
RIFATER COMPONENT PYRAZINAMIDE
NCGC00015833-09
Pyrazinamdie
SMR000036662
Pirazinamide [DCIT]
Pyrazinamidum (INN-Latin)
Pirazinamida (INN-Spanish)
PYRAZINAMIDE (MART.)
PYRAZINAMIDE [MART.]
2-carbamyl pyrazine
PYRAZINAMIDE (USP-RS)
PYRAZINAMIDE [USP-RS]
PYRAZINAMIDE (EP MONOGRAPH)
PYRAZINAMIDE (USP IMPURITY)
Pyrazinamide (USP:INN:BAN:JAN)
PYRAZINAMIDE [EP MONOGRAPH]
PYRAZINAMIDE [USP IMPURITY]
PYRAZINAMIDE (USP MONOGRAPH)
PYRAZINAMIDE [USP MONOGRAPH]
D-50 (VAN)
alpha-pyrazinamide
CAS-98-96-4
Pyrazinamide (TN)
SR-01000076077
Pyrazinamid
pyrazine amide
AZT + Pyrazinamide combination
Pyrazine-2-carboxylic acid amide
Pirazinecarboxamide
pyrazinamide tablet
Pyrazinamide,(S)
Prestwick_811
Pyranzinoic acid amide
2-pyrazine carboxamide
Spectrum_000902
Pyrazinamide (Standard)
Opera_ID_735
pyrazine, 2-carbamoyl-
Prestwick0_000514
Prestwick1_000514
Prestwick2_000514
Prestwick3_000514
Spectrum2_001305
Spectrum3_001046
Spectrum4_001186
Spectrum5_001026
Lopac-P-7136
PYRAZINAMIDE [MI]
PYRAZINAMIDE [INN]
PYRAZINAMIDE [JAN]
CHEMBL614
P 7136
PRAZINOIC ACID AMIDE
PYRAZINAMIDE [HSDB]
WLN: T6N DNJ BVZ
2-CARBOXAMIDOPYRAZINE
PYRAZINAMIDE [VANDF]
pyrazine-2-carboximidic acid
Lopac0_001011
SCHEMBL24102
BSPBio_000467
BSPBio_002572
KBioGR_001851
KBioSS_001382
MLS002222347
BIDD:GT0228
DivK1c_000241
PYRAZINAMIDE [WHO-DD]
PYRAZINAMIDE [WHO-IP]
SPECTRUM1500518
SPBio_001369
SPBio_002388
BPBio1_000515
GTPL7287
HMS500M03
HY-B0271R
KBio1_000241
KBio2_001382
KBio2_003950
KBio2_006518
KBio3_001792
Pyrazinamide (JP18/USP/INN)
2-(AMINOCARBONYL)PYRAZINE
J04AK01
NINDS_000241
BDBM228814
HMS1569H09
HMS1920N08
HMS2092E09
HMS2096H09
HMS2235G17
HMS3259O04
HMS3263K03
HMS3371G09
HMS3655A10
HMS3713H09
KUC109577N
Pharmakon1600-01500518
PYRAZINAMIDE [ORANGE BOOK]
BCP30257
HY-B0271
KSC-27-052E
WZB81781
Tox21_110237
Tox21_202059
Tox21_302771
Tox21_501011
CCG-39243
NSC757304
PYRAZINAMIDUM [WHO-IP LATIN]
s1762
STK801661
AKOS000120280
Tox21_110237_1
AP27270
DB00339
LP01011
NC00534
NSC-757304
Pyrazinecarboxamide, analytical standard
SDCCGSBI-0050984.P005
IDI1_000241
PYRAZINAMIDE COMPONENT OF RIFATER
NCGC00015833-01
NCGC00015833-02
NCGC00015833-03
NCGC00015833-04
NCGC00015833-05
NCGC00015833-06
NCGC00015833-07
NCGC00015833-08
NCGC00015833-10
NCGC00015833-11
NCGC00015833-12
NCGC00015833-15
NCGC00015833-16
NCGC00015833-25
NCGC00090695-01
NCGC00090695-03
NCGC00090695-04
NCGC00090695-05
NCGC00090695-06
NCGC00090695-07
NCGC00256336-01
NCGC00259608-01
NCGC00261696-01
Pyrazinamide;Pyrazinoic acid amide;D-50
Pyrazinoic acid amide; pyrazinamide; PZA
CAS- 98-96-4
SY013550
TS-01626
SBI-0050984.P004
DB-002866
AB00052083
EU-0101011
NS00010008
P0633
SW196945-3
EN300-15621
C01956
D00144
D70481
AB00052083-16
AB00052083_17
AB00052083_18
AC-907/25014068
Q417571
SR-01000076077-1
SR-01000076077-4
SR-01000076077-6
BRD-K28667793-001-27-3
BRD-K28667793-001-28-1
Z33546644
Pyrazinamide, British Pharmacopoeia (BP) Reference Standard
Pyrazinamide, European Pharmacopoeia (EP) Reference Standard
2-Carbamylpyrazine ;Aldinamid ;Aldinamide; Pyrazinoic acid amide
Pyrazinamide, United States Pharmacopeia (USP) Reference Standard
InChI=1/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9
Pyrazinamide, Pharmaceutical Secondary Standard; Certified Reference Material
202-717-6