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Pyrazine

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Identification
Molecular formula
C4H4N2
CAS number
290-37-9
IUPAC name
pyrazine
State
State

Pyrazine is found in a liquid state at room temperature. It can also be described as a volatile liquid due to its relatively low boiling point.

Melting point (Celsius)
52.00
Melting point (Kelvin)
325.15
Boiling point (Celsius)
115.50
Boiling point (Kelvin)
388.65
General information
Molecular weight
80.09g/mol
Molar mass
80.0890g/mol
Density
1.0310g/cm3
Appearence

Pyrazine appears as a colorless liquid. It possesses a distinctive, sweet odor that is reminiscent of nutty and roast-like aromas. This compound crystallizes in the form of white needles.

Comment on solubility

Solubility of Pyrazine

Pyrazine, with the chemical formula C4H4N2, is a heterocyclic aromatic compound that exhibits interesting solubility characteristics. Generally, pyrazine is moderately soluble in water. This solubility is influenced by several factors:

  • Polarity: Pyrazine is polar due to the presence of nitrogen atoms in the ring structure, which facilitates its interaction with polar solvents like water.
  • Temperature: Solubility in water tends to increase with temperature, enabling greater dissolution at elevated temperatures.
  • Solvent Interaction: It is also soluble in various organic solvents, such as alcohols and ether, which can be attributed to its molecular structure.

When discussing the solubility of pyrazine, it's important to note that:

  • The compound may form hydrogen bonds, enhancing its solubility in polar solvents.
  • It has low solubility in nonpolar solvents due to a lack of significant interactions.

As stated in literature, "the behavior of pyrazine in different solvents can open pathways for its application in various fields," underscoring the importance of understanding its solubility. Overall, while pyrazine is not the most hydrophilic compound, its moderate solubility in polar solvents makes it useful in both chemical and industrial applications.

Interesting facts

Interesting Facts about Pyrazine

Pyrazine is a fascinating organic compound known for its unique structure and versatile applications. Here are some interesting attributes that highlight its significance in the scientific community:

  • Structure: Pyrazine is a six-membered aromatic heterocycle containing two nitrogen atoms. This specific arrangement contributes to its unique chemical properties.
  • Synthetic Pathways: There are several methods for synthesizing pyrazine, including the condensation of α,β-unsaturated carbonyl compounds with hydrazine or through the reaction of diketones with hydrazine. This versatility makes it an interesting target for synthetic chemists.
  • Biological Activity: Studies have shown that pyrazine derivatives exhibit various biological activities, including antimicrobial and antitumor properties. This has sparked interest in utilizing these derivatives in pharmaceutical applications.
  • Aromatic Flavor: Pyrazine imparts a distinctive nutty, roasted aroma to various food products. It is commonly found in coffee, popcorn, and other cooked foods, making it a key compound in flavor chemistry.
  • Energy Storage: Recent research has explored the potential of pyrazine-based compounds for use in battery technologies, particularly as charge storage materials due to their redox properties.

As noted by many researchers, *“Understanding compounds like pyrazine not only provides insights into their individual properties but also opens up avenues for innovation across numerous fields.”*

In summary, pyrazine stands out not just for its chemical structure but also for its broad applications in diverse domains such as food chemistry, pharmaceuticals, and energy technology. Its multifaceted nature makes it a compound worth studying for anyone interested in the wonders of organic chemistry.

Synonyms
PYRAZINE
290-37-9
1,4-Diazine
p-Diazine
Paradiazine
Piazine
1,4-Diazabenzene
pyrazin
1,4-Diazin
CCRIS 1331
pyrazine phase IV
EINECS 206-027-6
Piazine (obsol.)
pyrazine phase III
NSC 400221
NSC-400221
1, 4-Diazabenzene
DTXSID8049410
FEMA NO. 4015
UNII-2JKE371789
CHEBI:30953
PYRAZINE [FHFI]
PYRAZINE [MI]
MFCD00006122
2JKE371789
DTXCID7029370
pyrazine phase I
pyrazine phase II
Pyrazines
pDiazine
1,4-Diazabenzene; 1,4-Diazine; Paradiazine; Piazine; p-Diazine
1,4Diazabenzene
1,4Diazine
Pyrazine, >=99%
Pyrazine, >=99%, FG
Pyrazine, analytical standard
CHEMBL15797
STR04325
Tox21_202911
BBL027560
NSC400221
STL373491
AKOS006223200
Pyrazine, purum, >=98.0% (GC)
CS-W013756
NCGC00260457-01
BP-10420
CAS-290-37-9
DB-003769
NS00010841
P0544
EN300-72616
A819731
Q424284
F0001-0907
206-027-6