Skip to main content

Prop-2-ynyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate

ADVERTISEMENT
Identification
Molecular formula
C11H13NO2
CAS number
. As it is not a commonly traded chemical, the CAS number may not be readily available.
IUPAC name
prop-2-ynyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate
State
State

At room temperature, this compound is a liquid. It is a clear, almost colorless liquid with a density slightly higher than water, making it easy to handle in laboratory and industrial settings.

Melting point (Celsius)
-10.00
Melting point (Kelvin)
263.15
Boiling point (Celsius)
246.00
Boiling point (Kelvin)
519.15
General information
Molecular weight
179.20g/mol
Molar mass
179.2040g/mol
Density
1.0300g/cm3
Appearence

Prop-2-ynyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate is characterized by its pale yellow liquid appearance. It is typically clear and colorless, although variations in quality or production method may introduce slight color changes. Under room temperature, it typically maintains its liquid state, providing ease of handling for various applications.

Comment on solubility

Solubility of Prop-2-ynyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate

The solubility of prop-2-ynyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate (C11H13NO2) is influenced by several factors including its molecular structure, polarity, and the presence of functional groups.

Factors Influencing Solubility

  • Polarity: The presence of the carboxylate group can enhance solubility in polar solvents like water, while the hydrocarbon portions of the molecule tend to favor solubility in non-polar solvents.
  • Hydrogen Bonding: The ability of the molecule to form hydrogen bonds with solvent molecules can significantly affect its solubility; for example, amines can interact favorably with water.
  • Temperature: As temperature increases, the solubility generally increases for many organic compounds, including this one.

In practice, this compound may exhibit moderate solubility in various organic solvents such as ethanol or dimethyl sulfoxide (DMSO), but it may show limited solubility in water due to its relatively large hydrophobic character from the alkyl groups. Thus, experimentation is encouraged to determine precise solubility characteristics under specific conditions.

As a general guideline regarding its potential solubility, it's valuable to remember that many pyridine derivatives traditionally possess remarkable solubility profiles due to their structural features.

Interesting facts

Interesting Facts about Prop-2-ynyl 1-Methyl-3,6-Dihydro-2H-Pyridine-5-Carboxylate

Prop-2-ynyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate is a fascinating compound with intriguing properties and applications in various fields. Here are some engaging facts that highlight its significance:

  • Chemical Structure: The compound features a unique bicyclic structure combining a pyridine ring with an alkyne side group, making it a versatile building block in organic synthesis.
  • Synthetic Utility: Its structure allows it to serve as a valuable intermediate in the synthesis of various biologically active molecules, particularly in pharmaceuticals.
  • Biological Relevance: Variants of this pyridine derivative have been explored for their potential therapeutic benefits, particularly in the realm of neurological disorders.
  • Reactivity: The presence of both an alkyne and an ester in its functional groups provides opportunities for diverse chemical reactions, including nucleophilic attacks and cycloadditions.
  • Research Interest: Ongoing research is focused on understanding the mechanism of action of this compound and its derivatives in medicinal chemistry, which could lead to the development of new drugs.

As noted by one researcher, "The incorporation of unique functionalities in compounds like prop-2-ynyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate opens doors to innovative therapeutic strategies."
The exploration of this compound not only underscores the complexity and beauty of organic chemistry but also emphasizes the endless possibilities within the realm of synthetic organic compounds.

Synonyms
Arecaidine propargyl ester
35516-99-5
prop-2-ynyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate
DTXSID30274358
3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, 2-propynyl ester
3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, 2-butynyl ester,4-methylbenzenesulfonate
prop-2-ynyl 1-methyl-5,6-dihydro-2H-pyridine-3-carboxylate
1-Methyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid, 2-propynyl ester
NCGC00015006-01
Lopac-A-140
arecaidine-propargyl-ester
Lopac0_000136
GTPL295
CHEMBL128365
SCHEMBL13184690
CHEBI:92418
DTXCID40199503
BDBM50475680
CCG-204231
SDCCGSBI-0050124.P002
NCGC00015006-02
NCGC00015006-03
NCGC00015006-04
NCGC00015006-07
NCGC00162072-01
NCGC00162072-02
DB-409905
L000114
BRD-K23922020-075-01-1
BRD-K23922020-075-02-9
Q27074500
2-Propyn-1-yl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate
2-Propynyl 1-methyl-1,2,5,6-tetrahydro-3-pyridinecarboxylate #