Skip to main content

Acrylamide

ADVERTISEMENT
Identification
Molecular formula
C3H5NO
CAS number
79-06-1
IUPAC name
prop-2-enamide
State
State

At room temperature, acrylamide exists as a solid. Due to its ability to absorb moisture from the air, it can sometimes form a sticky paste. In its pure form, it is a stable compound, but precautions are often taken to avoid its polymerization or exposure to heat which can lead to decomposition.

Melting point (Celsius)
84.00
Melting point (Kelvin)
357.15
Boiling point (Celsius)
125.00
Boiling point (Kelvin)
398.15
General information
Molecular weight
71.08g/mol
Molar mass
71.0800g/mol
Density
1.1300g/cm3
Appearence

Acrylamide is a white, odorless, crystalline solid. It tends to absorb moisture from the air and can form a paste when exposed to moisture. The compound is typically encountered in its solid form, but it is soluble in water, ethanol, ether, and chloroform.

Comment on solubility

Solubility of Prop-2-enamide

Prop-2-enamide, also known as acrylamide, exhibits interesting solubility characteristics that are pivotal in various chemical applications. Its ability to dissolve in different solvents can significantly influence its behavior in chemical processes.

Key Solubility Traits:

  • Polar Solvent Solubility: Prop-2-enamide is highly soluble in water, a property attributed to its polar amide group. This allows it to interact favorably with water molecules.
  • Organic Solvents: It is also soluble in most organic solvents such as ethanol and acetone, which underscores its versatility in varied chemical environments.
  • Temperature Dependence: The solubility of prop-2-enamide can be enhanced by heating, which can alter its solvation dynamics.

To quote a noteworthy observation, "The capacity of a compound to dissolve is a fundamental trait influencing its utility in synthetic and analytical chemistry." Thus, the solubility of prop-2-enamide not only impacts its reactivity but also its practicality in formulations and reactions.

In conclusion, understanding the solubility profile of prop-2-enamide is essential in tailoring its use in different chemical scenarios, providing a gateway to exploring its full potential in the realm of chemistry.

Interesting facts

Interesting Facts about Prop-2-enamide

Prop-2-enamide, also known as acrylamide, is a fascinating compound with several significant applications and properties that make it an interesting subject of study in chemistry.

1. Versatile Applications

  • Industrial Use: Acrylamide is primarily used in the production of polyacrylamide, a polymer used for various purposes including water treatment, soil conditioning, and as a thickening agent in food products.
  • Research Applications: It serves as a crucial building block in the synthesis of complex organic compounds, helping chemists design molecules for pharmaceuticals and other chemical products.
  • Laboratory Techniques: Acrylamide is a key component in electrophoresis gels, often utilized in the separation of biomolecules such as proteins and nucleic acids.

2. Health and Safety Considerations

While prop-2-enamide has valuable uses, it also raises concerns regarding health and safety:

  • Potential Carcinogen: Acrylamide is considered a potential neurotoxin and has been classified as a probable human carcinogen based on studies primarily involving animal exposure.
  • Food Safety: It can form during the cooking of carbohydrate-rich foods at high temperatures, leading to regulatory scrutiny and food safety discussions.

3. Chemical Properties and Reactions

From a chemical perspective, prop-2-enamide is particularly intriguing:

  • Reactivity: It can undergo various chemical reactions, such as polymerization and electrophilic addition, making it a reactive species in organic synthesis.
  • Functional Group: The amide functional group present in acrylamide allows for hydrogen bonding, contributing to its solubility in polar solvents.

4. Environmental Impact

Research has shown that acrylamide can be released into the environment, which raises the need for:

  • Waste Management: Proper disposal techniques to mitigate environmental contamination.
  • Treatment Methods: Strategies to reduce acrylamide levels in wastewater and food products are actively being developed.

In summary, prop-2-enamide (acrylamide) is not just a common chemical compound; it is an area of active research with implications that extend from industrial applications to public health, making it a significant topic of study in contemporary chemistry.

Synonyms
ACRYLAMIDE
79-06-1
2-Propenamide
prop-2-enamide
Propenamide
Ethylenecarboxamide
Acrylic amide
Vinyl amide
Akrylamid
Acrylic acid amide
Acrylagel
Propeneamide
Optimum
2-Propeneamide
Amresco Acryl-40
Ethylene Carboxamide
Propenoic acid amide
Amid kyseliny akrylove
RCRA waste number U007
Acrylamide Monomer
Akrylamid [Czech]
CCRIS 7
Amide propenoic acid
NSC 7785
Porisutoron
HSDB 191
Amid kyseliny akrylove [Czech]
acryl amide
CHEBI:28619
Flokonit E
Aminogen PA
Acrylamide Monome
Flygtol GB
Stipix AD
EINECS 201-173-7
Superfloc 84
Cytame 5
UNII-20R035KLCI
Sursolan P 5
Solvitose 433
Sumitex A 1
Superfloc 900
Cyanamer P 35
Gelamide 250
Nacolyte 673
Versicol W 11
BRN 0605349
Magnafloc R 292
Sumirez A 17
Sumirez A 27
20R035KLCI
Aerofloc 3453
Cyanamer P 250
Praestol 2800
DTXSID5020027
Himoloc SS 200
Stokopol D 2624
ACYLAMIDE-
AI3-04119
Bio-Gel P 2
Reten 420
American Cyanamid KPAM
BioGel P-100
K-PAM
NSC-7785
MFCD00008032
American Cyanamid P-250
Dow ET 597
DTXCID6027
Taloflote
Pamid
AAM
Acrylamide, electrophoresis grade
NSC7785
EC 201-173-7
Acrylamide [UN2074] [Poison]
Acrylamide-13C
Himoloc OK 507
Percol 720
PAARK 123sh
ACRYLAMIDE (IARC)
ACRYLAMIDE [IARC]
ACRYLAMIDE (MART.)
ACRYLAMIDE [MART.]
PAA-1
Dow J 100
PAA 70L
PAM-50
Acrilamida
Q 41F
AP 273
ET 597
Acrylamide 1000 microg/mL in Methanol
CAS-79-06-1
J 100
P 250
P 300
Propenoic acid, amide
UN2074
RCRA waste no. U007
acrylarnide
Acrylamide (1.0 mg/mL in Deionized water with 0.1% Formic Acid)
Amide propenoate
2-propene amide
acryloic acid amide
1HC
37 - Acrylamide
Acrylamide, 97%
Bio Gel P2
Bio Gel P-2
Bio-Gel P-2
ACRYLAMIDE [MI]
CH2CHCONH2
ACRYLAMIDE [HSDB]
bmse000392
Acrylamide Solution, 40%
Acrylamide, >=98.0%
Acrylamide, >=99.9%
RCRA Waste Numbrt U007
WLN: ZV1U1
PROPENAMIDE (50%)
Acrylamide_RamanathanGurudeeban
BIDD:ER0629
Acrylamide, analytical standard
CHEMBL348107
GTPL4553
Acrylamide, for synthesis, 99%
2-Propenamide;Acrylic acid amide
USEPA Pesticide Code: 600008
BCP25183
MLA39924
Tox21_201526
Tox21_300145
BDBM50226193
MSK001221
NSC116573
NSC116574
NSC116575
NSC118185
STL282727
788 - Acrylamide analysis in snacks
881 - Acrylamide analysis in coffee
AKOS000120965
Ethylene monoclinic tablets carboxamide
Acrylamide, purum, >=98.0% (GC)
FA14017
NSC-116573
NSC-116574
NSC-116575
NSC-118185
UN 2074
Acrylamide Monomer (ca. 50% in Water)
Acrylamide Monomer [for Electrophoresis]
NCGC00090736-01
NCGC00090736-02
NCGC00090736-03
NCGC00090736-04
NCGC00090736-05
NCGC00253932-01
NCGC00259076-01
Acrylamide Monomer, [for Electrophoresis]
Acrylamide, SAJ first grade, >=98.0%
FP176974
Polyacrylamide, average Mn 200W-1400W
DB-124507
DB-253723
A0139
A1132
A2625
Acrylamide, Ultrapure, Electrophoresis Grade
NS00009623
EN300-20803
AcrylamideRNase, DNase, Protease None detected
C01659
G77307
Acrylamide, suitable for electrophoresis, >=99%
A839565
Acrylamide, for electrophoresis, >=99.0% (GC)
Q342939
Acrylamide, for molecular biology, >=99% (HPLC)
Acrylamide, certified reference material, TraceCERT(R)
Acrylamide, for electrophoresis, >=99% (HPLC), powder
BC269F2E-D242-48E1-87E4-E51DB86FF0A8
F8880-6341
InChI=1/C3H5NO/c1-2-3(4)5/h2H,1H2,(H2,4,5
Acrylamide, for Northern and Southern blotting, powder blend
Acrylamide, Vetec(TM) reagent grade, suitable for electrophoresis
201-173-7
9082-06-8