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Potassium Cloxacillin

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Identification
Molecular formula
C19H17ClKN3O5S
CAS number
7081-44-9
IUPAC name
potassium;3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
State
State

At room temperature, potassium cloxacillin is typically found as a solid, specifically in powder form. It is stable under normal conditions of use and storage, though it should be kept away from moisture and acidic or alkaline substances to prevent potential degradation.

Melting point (Celsius)
200.00
Melting point (Kelvin)
473.15
Boiling point (Celsius)
691.90
Boiling point (Kelvin)
965.05
General information
Molecular weight
475.95g/mol
Molar mass
475.9530g/mol
Density
1.5803g/cm3
Appearence

Potassium cloxacillin appears as a white to off-white crystalline powder. It is usually supplied in the form of a lyophilized powder, facilitating its use in various pharmaceutical formulations. Its crystalline nature often gives it a slight sheen under bright light.

Comment on solubility

Solubility of Potassium 3,3-Dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

The solubility of the compound potassium 3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate (C19H17ClKN3O5S) is influenced by several factors that affect its interaction with solvents. Below are some key points regarding its solubility:

  • Polar Solvents: The presence of the polar functional groups in the structure, especially the carboxylate group, suggests that this compound may have increased solubility in polar solvents such as water.
  • Non-Polar Solvents: Conversely, the 2-phenoxyacetyl moiety may hinder solubility in non-polar solvents due to the overall structural complexity and hydrophilicity.
  • pH Sensitivity: Solubility can vary with pH; the carboxylate group can ionize in basic conditions, further enhancing solubility in aqueous solutions.
  • Temperature Effects: As with many compounds, increasing temperature may also increase solubility, especially in solvents where solvation dynamics are favorable.

Overall, while we can assume moderate to high solubility in aqueous systems due to its ionic nature from the potassium ion and carboxylate moiety, empirical testing is essential for precise solubility data under various conditions. As the old adage goes, "The proof of the pudding is in the eating," implying that practical experimentation is crucial for understanding solubility fully.

Interesting facts

Interesting Facts about Potassium; 3,3-Dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

This compound is a fascinating example in the realm of medicinal chemistry and has garnered attention due to its unique structure and potential therapeutic applications. Here are some intriguing insights:

Structural Features

  • Bicyclic Framework: The compound features a bicyclo[3.2.0] structure, which contributes to its rigidity and can influence its biological activity.
  • Thia and Amidic Groups: The presence of sulfur in the thia group and an amide linkage adds to the chemical versatility, affecting how the compound interacts with biological targets.

Biological Significance

  • Pharmacological Potential: Compounds with this structure may exhibit a range of pharmacological effects, making them candidates for drug development.
  • Enzyme Inhibition: The unique functional groups may allow the compound to inhibit specific enzymes, which is pivotal in treating various diseases.

Applications and Implications

Research into this compound can lead to advancements in:

  • Antibiotic Discovery: Due to its structural qualities, this compound might provide a scaffold for new antibiotic agents.
  • Cancer Treatment: Investigating its potential as an anticancer agent could uncover important therapeutic pathways.

As with many compounds, the opportunity for future research and development is vast. As one chemist put it, "The complexity of a molecule often hides infinite possibilities for its application." Indeed, the journey of exploring this compound is just as important as its potential uses!

Synonyms
Phenoxymethylpenicillinic acid potassium salt
SMR000875249
MLS001333167
MLS001333168
CHEMBL1905582
SCHEMBL11465923
AKOS026750030
NCGC00094753-01
NCGC00094753-02
PD055371
DB-042149
potassium;3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate