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Cloxacillin potassium

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Identification
Molecular formula
C19H17ClKN3O5S
CAS number
7081-44-9
IUPAC name
potassium;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
State
State

At room temperature, cloxacillin potassium is a solid. It is typically supplied as a crystalline powder for the preparation of oral or parenteral pharmaceutical formulations.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
210.00
Boiling point (Kelvin)
483.15
General information
Molecular weight
493.55g/mol
Molar mass
493.5490g/mol
Density
1.4500g/cm3
Appearence

Cloxacillin potassium appears as a white to off-white crystalline powder. It is odorless or may have a very faint odor.

Comment on solubility

Solubility of Potassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

The solubility of potassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate is a subject of interest due to its complex structure and various factors that influence its interaction with solvents.

Key considerations regarding solubility include:

  • Nature of the solvent: Polar solvents, such as water, typically enhance the solubility of ionic or polar compounds, while non-polar solvents are better suited for hydrophobic substances.
  • Presence of functional groups: The compound contains both polar and non-polar functional groups, which can affect its solubility in mixed solvent systems.
  • Influence of temperature: Higher temperatures generally increase solubility for many compounds by providing the energy needed to overcome lattice energy and dissolve solute molecules.

Understanding the solubility can also depend on the following:

  • pH Levels: The solubility can vary with pH, particularly for compounds containing acidic or basic moieties.
  • Ionic Strength: The presence of salts in solution may also influence solubility by altering the interaction dynamics among ions.

In conclusion, while definitive solubility data for potassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate may vary, it is clear that a multitude of factors must be considered for a comprehensive understanding of its solubility behavior. As research progresses, further insights into its solubility characteristics and potential applications will undoubtedly emerge.

Interesting facts

Interesting Facts about Potassium (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

This compound is a fascinating example of a complex bicyclic structure featuring both a thiazolidine and a bicyclo configuration. It is important to note that this compound holds significant relevance in the field of medicinal chemistry.

Key Characteristics

  • Unique Structural Features: The bicyclic system, with its distinct arrangements of atoms, contributes to the compound's unique chemical properties and biological activities.
  • Pharmaceutical Implications: Compounds similar to this one are often studied for their potential therapeutic effects, particularly in antibiotic or anti-inflammatory applications.
  • Stereochemistry: The (2S,5R,6R) configuration indicates that this molecule has specific spatial arrangements that can significantly influence its reactivity and interactions with biological targets.

The presence of the phenoxyacetyl group is also notable, as it can enhance the compound's ability to interact with specific enzymes or receptors. As chemists explore the nuances of structure-activity relationships, understanding such modifications can lead to the development of more effective drug candidates.

Quote from the Literature

"The intricate design of complex organic molecules, like this compound, reveals the art and science of synthetic chemistry, where every subtle change can lead to remarkable differences in biological effectiveness."

In summary, potassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate is not just a chemical entity; it stands at the intersection of molecular design and therapeutic innovation, showcasing the profound impact of chemistry on health and medicine.