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Glutarimide

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Identification
Molecular formula
C5H7NO2
CAS number
108-95-2
IUPAC name
piperazine-2,5-dione
State
State

At room temperature, glutarimide is in the solid state, appearing as a fine powder or crystalline solid.

Melting point (Celsius)
84.00
Melting point (Kelvin)
357.00
Boiling point (Celsius)
196.00
Boiling point (Kelvin)
469.00
General information
Molecular weight
99.12g/mol
Molar mass
99.1180g/mol
Density
1.2900g/cm3
Appearence

Glutarimide appears as a white crystalline solid at room temperature. It is typically supplied as a fine powder.

Comment on solubility

Solubility of Piperazine-2,5-dione

Piperazine-2,5-dione, with the chemical formula C4H6N2O2, exhibits interesting solubility characteristics that are noteworthy for various applications in chemical science.

In general, the solubility of piperazine-2,5-dione can be summarized as follows:

  • Polar Solvents: It is known to be soluble in polar solvents such as water and methanol, which is attributed to the presence of its **hydrophilic** (water-attracting) functional groups.
  • Non-Polar Solvents: Conversely, piperazine-2,5-dione shows limited solubility in non-polar solvents like hexane or benzene. This is due to its polar nature, which does not favor interactions with non-polar substances.
  • Temperature Influence: The solubility may vary with temperature; it is often observed that higher temperatures can increase solubility in polar solvents.

Overall, while piperazine-2,5-dione is readily soluble in specific solvents, its ability to dissolve increases primarily in environments where solvent polarity aligns with its own characteristics. As one could say, “like dissolves like,” highlighting the importance of understanding solvent interactions in solubility studies.

Interesting facts

Interesting Facts about Piperazine-2,5-dione

Piperazine-2,5-dione, also known as an essential derivative of piperazine, is an intriguing compound in the field of organic chemistry. This compound exhibits a unique structure that has captured the interest of scientists and researchers alike.

Key Characteristics

  • Versatile Derivative: Piperazine-2,5-dione serves as a core structure for numerous bioactive compounds and pharmaceuticals, highlighting its importance in drug development.
  • Applications: It has been investigated for its potential use in treating various health conditions, including anxiety disorders and schizophrenia.
  • Building Block: The compound acts as a valuable building block in the synthesis of more complex molecules, making it essential for chemists working on novel therapeutic agents.

The Science Behind Its Significance

The structure of piperazine-2,5-dione features a 6-membered ring, which contributes to its chemical reactivity and interaction with biological systems. This compound is often involved in:

  • Pharmacological Studies: Research has indicated that derivatives of piperazine-2,5-dione exhibit diverse pharmacological activities, making them potential candidates for drug design.
  • Bioactivity: Its reactivity allows it to participate in various biochemical pathways, enhancing its appeal as a compound of interest in medicinal chemistry.

Quote from the Field

As one scientist noted, "Piperazine derivatives serve as a window into the potential of therapeutic interventions in complex disorders." This highlights the growing belief in the compound's prospects as a crucial player in developing new treatment strategies.

In conclusion, piperazine-2,5-dione is more than just a simple organic compound; it is a promising platform for innovation in medicinal chemistry and drug design, paving the way for new pursuits in scientific research.

Synonyms
Piperazine-2,5-dione
2,5-Piperazinedione
106-57-0
GLYCINE ANHYDRIDE
2,5-DIKETOPIPERAZINE
2,5-Dioxopiperazine
Cycloglycylglycine
Cyclodiglycine
Glycylglycine lactam
Cyclo(glycylglycyl)
Diglycolyl diamide
diglycolyldiamide
Glycine, bimol. cyclic peptide
Cyclic(glycylglycyl)
MFCD00006009
Piperazinedione
Glycine, N-glycyl-, cyclic peptide
EINECS 203-411-5
NSC 26345
UNII-240L69DTV7
BRN 0112112
.alpha.,.gamma.-Diacipiperazine
CHEBI:16535
NSC-26345
DTXSID8059342
240L69DTV7
2,5-PIPERAZINEDIONE [MI]
5-24-05-00294 (Beilstein Handbook Reference)
NSC26345
Piperazine-2,5-dione (Glycine Anhydride)
alpha,gamma-Diacipiperazine
Glycine Anhydride(2,5-Piperazinedione)
Glycocoll Anhydride
cyclo-(Gly-Gly)
2,5Dioxopiperazine
2,5diketopiperazine
Glycine, cyclic peptide
piperazine-2,5-quinone
alpha,gammaDiacipiperazine
SCHEMBL66638
CHEMBL125229
DTXCID5032997
Glycine, Nglycyl, cyclic peptide
2,5-Diazacyclohexane-1,4-dione
Glycine anhydride, cyclic dipeptide
BCP20475
STK741583
TETRAHYDRO-2,5-PYRAZINEDIONE
AKOS001056505
Glycine anhydride;2,5-Piperazinedione
FD05300
PS-4716
SY011208
CS-0046695
EU-0051025
G0100
NS00015771
CYCLO-GLYCYLGLYCINE (3,3,6,6-D4)
EN300-16993
C02777
F11382
AC-907/30002028
BRD-K95941975-001-01-5
Q27101960
Z56854487
F0278-0016