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Salol

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Identification
Molecular formula
C13H10O3
CAS number
118-55-8
IUPAC name
phenyl 2-hydroxybenzoate
State
State

Salol is a solid at room temperature, appearing as a crystalline powder.

Melting point (Celsius)
41.50
Melting point (Kelvin)
314.70
Boiling point (Celsius)
306.50
Boiling point (Kelvin)
579.70
General information
Molecular weight
214.22g/mol
Molar mass
214.2160g/mol
Density
1.4430g/cm3
Appearence

Salol appears as a white crystalline solid or powder. It is known for its somewhat pleasant aromatic odor, reminiscent of wintergreen oil, which is characteristic of salicylates.

Comment on solubility

Solubility of Phenyl 2-Hydroxybenzoate

The solubility of phenyl 2-hydroxybenzoate, also known as salicylic acid phenyl ester, is influenced by several factors due to its molecular structure. Here are some key points to consider:

  • Polar and Non-polar Nature: As a compound featuring a phenyl group and a hydroxyl group, it exhibits both polar and non-polar characteristics, which can impact its solubility in different solvents.
  • Solvent Interactions: Generally, phenyl 2-hydroxybenzoate tends to be soluble in organic solvents such as ethanol, methanol, and chloroform due to its non-polar aromatic character.
  • Water Solubility: However, its solubility in water is limited. The hydroxyl group can form hydrogen bonds, but the overall hydrophobic nature of the phenyl group hinders extensive solvation in aqueous environments.
  • Temperature Dependence: The solubility of phenyl 2-hydroxybenzoate may increase with temperature, allowing for greater dissolution in hot solvents.

In summary, while phenyl 2-hydroxybenzoate is more soluble in organic solvents due to its structure, its limited solubility in water highlights the importance of understanding solvent interactions for practical applications in various fields.

Interesting facts

Interesting Facts About Phenyl 2-Hydroxybenzoate

Pheynl 2-hydroxybenzoate is an intriguing compound with a range of applications in chemistry and industry. Here are some noteworthy points:

  • Chemical Class: This compound belongs to the class of esters, which are derived from acids and alcohols. Its structure contributes to its properties, playing a significant role in various chemical reactions.
  • Antimicrobial Properties: Phenyl 2-hydroxybenzoate exhibits antimicrobial features, making it valuable in the manufacturing of preservatives for personal care products. This helps in extending the shelf life of lotions, creams, and other cosmetic formulations.
  • Pharmaceutical Applications: Due to its ability to inhibit microbial growth, phenyl 2-hydroxybenzoate is often utilized in pharmaceuticals, particularly in formulations aimed at treating skin infections.
  • Structural Versatility: The presence of both phenyl and hydroxyl groups in its structure allows for varied reactivity. This enables chemists to use it as a starting material or intermediate in organic synthesis.
  • Environmental Impact: Like many compounds, its usage comes with environmental responsibilities. Awareness and regulations around its use are critical to ensuring safe practices in industrial applications.

In summary, phenyl 2-hydroxybenzoate is more than just a chemical compound; it plays a crucial role in enhancing the efficacy and longevity of products we use daily. As researchers and students delve deeper into this compound, they can uncover new potential uses and understand its broader impacts on health and environment. As the chemist Linus Pauling once said, "The best way to have a good idea is to have lots of ideas," and exploring compounds like phenyl 2-hydroxybenzoate undoubtedly fosters a wealth of innovation.

Synonyms
Phenyl salicylate
118-55-8
PHENYL 2-HYDROXYBENZOATE
Salol
Phenol salicylate
Salphenyl
Musol
2-Phenoxycarbonylphenol
Benzoic acid, 2-hydroxy-, phenyl ester
Salicylic acid, phenyl ester
2-Hydroxybenzoic acid phenyl ester
Phenyl-2-hydroxybenzoate
Fenylester kyseliny salicylove
Seesorb 201
2-Hydroxy-benzoic acid phenyl ester
Seesorb K 201
NSC 33406
CCRIS 4859
Phenyl salicylate [NF]
2-Hydroxybenzoic acid, phenyl ester
Salicylic Acid Phenyl Ester
EINECS 204-259-2
MFCD00002213
NSC-33406
Fenylester kyseliny salicylove [Czech]
BRN 0393969
DTXSID6021957
FEMA NO. 3960
CHEBI:34918
AI3-00195
28A37T47QO
SALOL [VANDF]
SALOL [HPUS]
SALOL [MART.]
Phenyl salicylate melting point standard
PHENYL SALICYLATE [MI]
DTXCID201957
PHENYL SALICYLATE [FHFI]
PHENYL SALICYLATE [VANDF]
PHENYL SALICYLATE [USP-RS]
PHENYL SALICYLATE [WHO-DD]
NCGC00090887-02
SALOL (MART.)
PHENYL SALICYLATE (USP-RS)
CAS-118-55-8
phenylsalicylate
UNII-28A37T47QO
phenyl-salicylate
phenyl salicylic acid
2Phenoxycarbonylphenol
salicylic phenyl ester
Phenyl 2hydroxybenzoate
WLN: QR BVOR
Oprea1_020651
Oprea1_771794
SCHEMBL24326
BIDD:ER0018
CHEMBL1339216
PHENYL SALICYLATE [INCI]
Phenyl salicylate, >=99%, FG
2Hydroxybenzoic acid, phenyl ester
HY-B1731
NSC33406
STR06361
Tox21_113459
Tox21_201811
Tox21_302949
Phenyl Salicylate, Crystal, Purified
STK052177
Benzoic acid, 2hydroxy, phenyl ester
AKOS000121203
Tox21_113459_1
DB11071
FP34589
PS-7960
NCGC00090887-01
NCGC00090887-03
NCGC00090887-04
NCGC00090887-05
NCGC00091499-03
NCGC00256612-01
NCGC00259360-01
AC-11469
Phenyl salicylate, ReagentPlus(R), 99%
DB-024372
CS-0013740
NS00010218
S0017
EN300-18348
SBI-0653857.0001
AB00443435-03
Phenyl salicylate, Vetec(TM) reagent grade, 98%
Q421259
SR-01000883691
SR-01000883691-1
BRD-K44091963-001-01-5
Phenyl salicylate - Melting point 41.82 masculineC
Z57206005
Mettler-Toledo Calibration substance ME 30034252, Phenyl salicylate
204-259-2
Mettler-Toledo Calibration substance ME 30034252, Phenyl salicylate, traceable to primary standards
Phenyl salicylate melting point standard, approximately 41 degrees, United States Pharmacopeia (USP) Reference Standard
Phenyl salicylate melting point standard, Pharmaceutical Secondary Standard; Certified Reference Material