N,N,4-Trimethylaniline | Solubility of Things

Identification

Molecular formula

C₉H₁₃N

CAS number

99-97-8

IUPAC name

N,N,4-trimethylaniline

State

N,N,4-Trimethylaniline is typically found as a liquid at room temperature.

Melting point (Celsius)

-20.00

Melting point (Kelvin)

253.15

Boiling point (Celsius)

225.00

Boiling point (Kelvin)

498.15

General information

Molecular weight

135.21g/mol

Molar mass

135.2110g/mol

Density

0.9000g/cm³

Appearence

N,N,4-Trimethylaniline appears as a colorless to light yellow liquid. It is notable for its characteristic aromatic amine odor, which is typical for such compounds. Upon exposure to air or light, it may darken.

Comment on solubility

Solubility of N,N,4-trimethylaniline

N,N,4-trimethylaniline, with the chemical formula C₁₀H₁₅N, is a compound that exhibits specific solubility characteristics based on its molecular structure.

This compound is noted for its moderate solubility in organic solvents, while it is generally insoluble in water. The reasons for this behavior include:

Molecular Structure: The presence of three methyl groups on the aniline structure contributes to hydrophobic interactions, which reduces its affinity for polar solvents like water.
Polarity: As a relatively non-polar molecule, it prefers non-polar environments and thus dissolves better when interacting with organic solvents such as ethanol or ether.
Hydrophobicity: The dense packing of the methyl groups increases the hydrophobic character, further decreasing solubility in aqueous solutions.

In summary, while N,N,4-trimethylaniline may be utilized effectively in various organic solvent applications, its limited water solubility makes it less suitable for aqueous systems. This characteristic is important for its practical applications in fields such as dye synthesis and chemical manufacturing.

Interesting facts

Interesting Facts about N,N,4-Trimethylaniline

N,N,4-trimethylaniline is a fascinating compound primarily known for its role in organic chemistry and industrial applications. As a derivative of aniline, this compound has several interesting aspects:

Structure and Function: N,N,4-trimethylaniline contains a benzene ring substituted with three methyl groups and an amino group. This unique structure contributes to its reactivity and utility in various chemical transformations.
Applications: This compound is often used as a intermediate in the synthesis of dyes, pigments, and pharmaceuticals. Its ability to undergo electrophilic aromatic substitution makes it valuable in organic synthesis.
Biological Relevance: Like many aniline derivatives, N,N,4-trimethylaniline can mimic certain biological functions and has been studied for its potential in pharmaceuticals. Its interactions with biological systems can open doors for new drug discovery.
Toxicity Considerations: Despite its utility, it's important to note that N,N,4-trimethylaniline may present toxicity risks in certain concentrations. Safety protocols should always be upheld when handling this compound, as aniline derivatives are known for their effects on human health.
Research Opportunities: The unique properties of N,N,4-trimethylaniline make it a subject of research in fields such as materials science and catalysis. Its potential as a catalyst in specific chemical reactions makes it an exciting area of study.

Overall, the study of N,N,4-trimethylaniline unfolds a narrative of chemical versatility, balancing useful applications with the need for careful handling. As scientists continue to explore its properties, there are likely to be even more exciting developments surrounding this compound in the future.

Synonyms

N,N-Dimethyl-p-toluidine

N,N,4-TRIMETHYLANILINE

99-97-8

Dimethyl-p-toluidine

Benzenamine, N,N,4-trimethyl-

Dimethyl-4-toluidine

N,N-Dimethyl-4-methylaniline

N,N,4-Trimethylbenzenamine

p-(Dimethylamino)toluene

p-Methyl-N,N-dimethylaniline

N,N-Dimethyl-p-tolylamine

p,N,N-Trimethylaniline

p-Toluidine, N,N-dimethyl-

NSC 1785

Dimetil-p-toluidina

4-Dimethylaminotoluene

dimethyltolylamine

Dimetil-p-toluidina [Italian]

CCRIS 1001

1-(Dimethylamino)-4-methylbenzene

N,N-Dimethyl-4-toluidine

EINECS 202-805-4

UNII-S8XC5939VU

S8XC5939VU

DTXSID0021832

HSDB 8202

NSC-1785

4,N,N-Trimethylaniline

DTXCID401832

N,N-Dimethyl-p-methylphenylamine

EC 202-805-4

N,N-DIMETHYL-P-TOLUIDINE [IARC]

NL 65-100

N,N-Dimethyl-para-toluidine

aniline, N,N,4-trimethyl-

p-N,N-Trimethylaniline

CAS-99-97-8

N,N-DIMETHYL-P-TOLUIDINE (IARC)

dimethyl-para-toluidine

MFCD00008316

Dimetilptoluidina

Benzeneamine,N,N,4-trimethyl-

Dimethylptoluidine

N,NDimethylptoluidine

N,4-Trimethylaniline

N,NDimethylptolylamine

p,N,NTrimethylaniline

N,N,4Trimethylaniline

p(Dimethylamino)toluene

pMethylN,Ndimethylaniline

N,NDimethyl4methylaniline

dimethyl-(p-tolyl)-amine

Benzenamine,N,4-trimethyl-

SCHEMBL28378

Benzenamine, N,N,4trimethyl

MLS001050174

Benzenamine, N,N,4-trimethyl

4-dimethylamino-1-methylbenzene

4,N,N-Trimethylaniline, 99%

CHEMBL1462714

N,N-DIMETHYL-P-TOLUIDENE

DIMETHYLTOLYLAMINE [INCI]

NSC1785

N,N-DIMETHYL-1,4-TOLUIDINE

Tox21_201370

Tox21_300062

AC-368

AKOS015915159

NCGC00091397-01

NCGC00091397-02

NCGC00091397-03

NCGC00254201-01

NCGC00258922-01

SMR001216586

D0807

NS00002247

E75885

EN300-7266829

4,N,N-Trimethylaniline, purum, >=98.0% (GC)

Q2051705

Z1002998236

platinum(2+); 4-(1H-pyrazol-4-ylmethyl)-1H-pyrazole; tetrachloride

202-805-4