Interesting facts
Interesting Facts about N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine; hydrochloride
N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine; hydrochloride is a compound recognized for its significance in both the pharmaceutical realm and chemical research. Here are some notable insights:
- Pharmaceutical Relevance: This compound is often studied for its potential as a therapeutic agent. It belongs to a class of drugs known for their antidepressant and anxiolytic properties, making it of interest in mental health treatments.
- Phenothiazine Derivative: The structure includes a phenothiazine moiety, which contributes to various biological activities. Phenothiazine compounds are historically recognized for their role in the development of antipsychotic medications.
- Applications in Research: Beyond its medicinal uses, this compound is utilized in laboratory settings to explore drug behavior, interactions, and efficacy, assisting scientists in understanding complex biochemical pathways.
- Structure-Activity Relationship (SAR): Researchers frequently investigate the SAR of such compounds to optimize their pharmacological profile, with modifications to the dimethyl and amine substitutions being a focal point in study.
- Chirality Importance: The presence of chirality in the compound adds another layer of complexity and intrigue. How the stereochemistry affects its biological interactions can provide deep insights into enantiomeric effects in pharmacology.
As a compound with multifaceted applications in both medicine and research, N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine; hydrochloride exemplifies the intricate relationship between chemical structure and biological function.
Overall, its study not only supports the advancement of therapeutic medications but also enriches our understanding of chemical behavior in biological systems. As we uncover more about such substances, the potential for novel treatments continues to expand.
Synonyms
PROMETHAZINE HYDROCHLORIDE
58-33-3
Promethazine Hcl
Phenergan
N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine hydrochloride
Fenergan
Farganesse
Promethacon
Promethegan
Diprasine
Fellozine
Ganphen
Plletia
Remsed
Prometh Fortis
Prometh Plain
Promethazine.HCl
Mymethazine Fortis
Promethazine (hydrochloride)
Promethiazin
Allerfen
Anergan 25
Diprazin
Duplamin
Goodnight
Hibechin
Histantil
Kinetosin
Lergigan
Phenadoz
Pipolfen
Pipolphen
Promantine
Proneurin
Bonnox
Closin
Frinova
Phencen
Primine
Soporil
Dorme
Prome
Promethazine chloride
Eusedon Mono
Phenergan Fortis
Zipan-25
PMS Promethazine
Promethazine Plain
V GAN
Romergan
Prorex
PHENERGAN PLAIN
ZIPAN-50
Promethazine monohydrochloride
Pyrethia
Phenergan hydrochloride
CCRIS 5873
Genphen
HL 8700
Phanergan D
UNII-R61ZEH7I1I
EINECS 200-375-2
N-(2-Dimethylaminopropyl-1)phenothiazine hydrochloride
R61ZEH7I1I
MFCD00012652
NSC 231688
CHEBI:8462
N-(2'-Dimethylamino-2'-methyl)ethylphenothiazine hydrochloride
DTXSID3021192
3277 R.P.
10-(3-Dimethylaminoisopropyl)phenothiazine hydrochloride
10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride
10-(2-Dimethylamino-1-propyl)phenothiazine hydrochloride
NSC-231688
10-(2-Dimethylaminopropyl)phenothiazine hydrochloride
MLS000069398
DTXCID801192
10-(2-(Dimethylamino)propyl)phenothiazine monohydrochloride
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride
Phenothiazine, 10-(2-(dimethylamino)-propyl)-, hydrochloride
(+-)-10-(2-(Dimethylamino)propyl)phenothiazine monohydrochloride
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, monohydrochloride
Avomine
Prometh
NSC231688
Promethazine hydrochloride [USP:JAN]
1435933-86-0
RP-3389
58-33-3 (HCl)
SMR000058379
Phenothiazine, 10-(2-(dimethylamino)propyl)-, monohydrochloride
MEPERGAN COMPONENT PROMETHAZINE HYDROCHLORIDE
Anergan 50
PHENERGAN VC COMPONENT PROMETHAZINE HYDROCHLORIDE
PHERAZINE DM COMPONENT PROMETHAZINE HYDROCHLORIDE
PHERAZINE VC COMPONENT PROMETHAZINE HYDROCHLORIDE
Promethazine hydrochloride 100 microg/mL in Acetonitrile
Promethiazin [German]
PROMETHAZINE DM COMPONENT PROMETHAZINE HYDROCHLORIDE
PROMETHAZINE VC COMPONENT PROMETHAZINE HYDROCHLORIDE
Promethazine hydrochloride (USP:JAN)
(+/-)-10-(2-(DIMETHYLAMINO)PROPYL)PHENOTHIAZINE MONOHYDROCHLORIDE
PROMETHAZINE HYDROCHLORIDE (MART.)
PROMETHAZINE HYDROCHLORIDE [MART.]
PROMETHAZINE HYDROCHLORIDE (USP-RS)
PROMETHAZINE HYDROCHLORIDE [USP-RS]
Promethazine hydrochloride [JAN]
PROMETHAZINE HYDROCHLORIDE (EP MONOGRAPH)
PROMETHAZINE HYDROCHLORIDE (USP IMPURITY)
PROMETHAZINE HYDROCHLORIDE [EP MONOGRAPH]
PROMETHAZINE HYDROCHLORIDE [USP IMPURITY]
PromethazineHydrochloride
PROMETHAZINE HYDROCHLORIDE (USP MONOGRAPH)
PROMETHAZINE HYDROCHLORIDE [USP MONOGRAPH]
10-(2-(DIMETHYLAMINO)PROPYL)PHENOTHIAZINE HYDROCHLORIDE
SR-01000002993
Promethazine HCI
Phenergan (TN)
Promethegan (TN)
V-Gan
DIPRAZINUM
component of Mepergan
CPD000058379
PRONASE [JAN]
Promethazine hydrochlorine
CAS-58-33-3
Opera_ID_1745
Hydrochloride, Promethazine
DIPRAZINUM [WHO-IP]
ROMERGAN HYDROCHLORIDE
SCHEMBL41904
MLS001074184
MLS002548850
PROMETHAZINIUM CHLORIDE
SPECTRUM1500510
CHEMBL1200750
HY-B0781R
PROMETHAZINI HYDROCHLORIDUM
HMS1570B18
HMS1920L16
Pharmakon1600-01500510
HY-B0781
N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine hydrochloride
Promethazine for peak identification
Tox21_202264
Tox21_302878
Tox21_500899
NSC757301
s4293
Promethazine HCl - Bio-X trade mark
PROMETHAZINE HYDROCHLORIDE tablet
10H-Phenothiazine-10-ethanamine, N,N,.alpha.-trimethyl-, monohydrochloride
AKOS016339657
PROMETHAZINE HYDROCHLORIDE PLAIN
CCG-207895
CS-3543
FD27182
KS-1385
LP00899
NC00471
NSC-757301
Promethazine hydrochloride (JP18/USP)
PROMETHAZINE HYDROCHLORIDE [MI]
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, monohydrochloride, (+-)-
Promethazine (hydrochloride) (Standard)
NCGC00089735-04
NCGC00094215-01
NCGC00094215-02
NCGC00094215-03
NCGC00094215-04
NCGC00094215-05
NCGC00256588-01
NCGC00259813-01
NCGC00261584-01
AC-12482
BP166198
PROMETHAZINE HYDROCHLORIDE [VANDF]
PROMETHAZINE HYDROCHLORIDE [WHO-DD]
PROMETHAZINE HYDROCHLORIDE [WHO-IP]
DB-053186
EU-0100899
NS00076255
P2029
SW197234-3
EN300-72728
D00480
D92182
P 4651
PROMETHAZINE HYDROCHLORIDE [ORANGE BOOK]
Promethazine.HCl, 1mg/ml in Dmf (as free base)
WLN: T C666 BN ISJ B1Y1&N1&1 &GH
A831833
PROMETHAZINI HYDROCHLORIDUM [WHO-IP LATIN]
SR-01000002993-2
SR-01000002993-7
PROMETHAZINE HYDROCHLORIDE COMPONENT OF MEPERGAN
Q27108086
F0138-3355
Z1151174635
PROMETHAZINE HYDROCHLORIDE COMPONENT OF PHENERGAN VC
PROMETHAZINE HYDROCHLORIDE COMPONENT OF PHERAZINE DM
PROMETHAZINE HYDROCHLORIDE COMPONENT OF PHERAZINE VC
N,N-dimethyl-1-(10-phenothiazinyl)-2-propanamine hydrochloride
N-(2'-Dimethylamino-2'-methylaethyl)-phenothiazin hydrochlorid
N-(2'-Dimethylamino-2-methylethyl)phenothiazine hydrochloride
PROMETHAZINE HYDROCHLORIDE COMPONENT OF PROMETHAZINE DM
PROMETHAZINE HYDROCHLORIDE COMPONENT OF PROMETHAZINE VC
Promethazine hydrochloride, VETRANAL(TM), analytical standard
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine;hydron;chloride
10H-Phenothiazine-10-ethanamine,N,.alpha.-trimethyl-, monohydrochloride
DIMETHYL[1-(10H-PHENOTHIAZIN-10-YL)PROPAN-2-YL]AMINE HYDROCHLORIDE
N,N-Dimethyl-1-(10H-phenothiazin-10-yl)-2-propanamine hydrochloride
Promethazine Hydrochloride 1.0 mg/ml in Dimethyl Sulfoxide (as free base)
Promethazine hydrochloride, European Pharmacopoeia (EP) Reference Standard
Promethazine hydrochloride, vial of 25 mg, certified reference material
(2RS)-N,N-Dimethyl-1-(10H-phenothiazin-10-yl)propan-2-ylamine monohydrochloride
10H-PHENOTHIAZINE-10-ETHANAMINE, N,N,.ALPHA.-TRIMETHYL-, MONOHYDROCHLORIDE, (+/-)-
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, hydrochloride (1:1)
10H-PHENOTHIAZINE-10-ETHANAMINE, N,N,alpha-TRIMETHYL-, MONOHYDROCHLORIDE, (+/-)-
10H-PHENOTHIAZINE-10-ETHANAMINE, N,N-ALPHA-TRIMETHYL-, MONOHYDROCHLORIDE
N,N-ALPHA-TRIMETHYL-10H-PHENOTHIAZINE-10-ETHANAMINE MONOHYDROCHLORIDE
Promethazine for peak identification, European Pharmacopoeia (EP) Reference Standard
Promethazine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
Promethazine hydrochloride, United States Pharmacopeia (USP) Reference Standard
PROMETHAZINE N-(2'-DIMETHYLAMINO-2'-METHYLETHYL)PHENOTHIAZINE HYDROCHLORIDE
200-375-2
N,N,a-Trimethyl-10H-phenothiazine-10-ethanamine hydrochloride;10-[2-(Dimethylamino)propyl]phenothiazine Hydrochloride;(2-Dimethylami no-2-methyl)ethyl-N-dibenzoparathiazine hydrochloride;Promethazine hydrochloride
N,N,a-Trimethyl-10H-phenothiazine-10-ethanamine hydrochloride;10-2-(Dimethylamino)propylphenothiazine Hydrochloride;(2-Dimethylami n o-2-methyl)ethyl-N-dibenzoparathiazine hydrochloride;Promethazine hydrochloride
Solubility of N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine; hydrochloride
The solubility of N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine; hydrochloride (C17H20N2S·HCl) is a critical aspect to understand for its application and handling. Being a hydrochloride salt, this compound typically exhibits improved solubility in water compared to its parent base. Below are key features regarding its solubility:
In summary, this compound demonstrates good solubility characteristics due to its ionic form, making it more accessible for biological and pharmaceutical applications. As noted, “solubility is not just a property, but a gateway to understanding the behavior of compounds in various environments.”