Interesting facts
Interesting Facts about N,N-Dimethyl-1-phenothiazin-10-yl-propan-2-amine
N,N-Dimethyl-1-phenothiazin-10-yl-propan-2-amine, often referred to for its intriguing structure and diverse applications, is a compound worth exploring. Here are some engaging facts:
- Pharmaceutical Applications: This compound is part of a class of phenothiazine derivatives, which have been extensively studied for their efficacy as antipsychotic medications. Its ability to influence neurotransmitter systems in the brain has made it a topic of interest in psychopharmacology.
- Complex Structure: The structure features a phenothiazine moiety, known for its unique bicyclic framework that consists of sulfur and nitrogen. This complex arrangement contributes to its chemical reactivity and interaction with biological targets.
- Mechanism of Action: Phenothiazines like this compound often work by blocking dopamine receptors in the brain. Thus, they help alleviate symptoms of various psychological disorders, making them crucial in modern psychiatry.
- Research Applications: Besides its medical applications, N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine is also subject to research in environmental chemistry and materials science, where studies are investigating its interactions with different agents.
- Historical Significance: The discovery of phenothiazines marked a turning point in the treatment of mental health conditions in the mid-20th century, ushering in an era of pharmacotherapy that has reshaped psychiatric treatment.
This compound stands as a testament to the intersection of organic chemistry and pharmacology, illustrating how small changes in molecular structure can lead to significant biological effects. As we delve deeper into its properties and functions, we continue to unveil the intriguing behaviors of chemical compounds.
Synonyms
promethazine
Proazamine
60-87-7
Diphergan
Protazine
Promethazin
Prometazin
Vallergine
Dimapp
Fargan
Procit
Promazinamide
Promezathine
Phenargan
Prothazin
Diprazine
Histargan
Phensedyl
Phargan
Tanidil
Thiergan
Pyrethiazine
Prometazina
Provigan
Fenazil
Lilly 1516
Avomine
Prorex
Antiallersin
Fenetazine
Phenerzine
Pipolphene
Proazaimine
Prometasin
Promethazinum
Promethiazine
Camergan
Iergigan
Metaryl
Pelpica
Pilothia
Pilpophen
Promacot
Promergan
Promesan
PromethazineHcl
Lilly 01516
Phenoject-50
Lercigan
Valergine
Pyrethia
N-(2'-Dimethylamino-2'-methyl)ethylphenothiazine
SKF 1498
Pro-50
Prometh
(2-Dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine
WY 509
Dimethylamino-isopropyl-phenthiazin
RP 3277
10-(2-Dimethylaminopropyl)phenothiazine
10-[2-(Dimethylamino)propyl]phenothiazine
N,N,alpha-Trimethyl-10H-phenothiazine-10-ethanamine
Romergan
N-Dimethylamino-2-methylethyl thiodiphenylamine
Prometazina [INN-Spanish]
Promethazinum [INN-Latin]
NCI-C60673
A-91033
10-(2-(Dimethylamino)-2-methylethyl)phenothiazine
Phenothiazine, 10-(2-dimethylaminopropyl)-
CCRIS 7056
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-
3277 RP
HSDB 3173
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine
10-(2-(Dimethylamino)propyl)phenothiazine
EINECS 200-489-2
UNII-FF28EJQ494
NSC 30321
NSC-30321
BRN 0088554
CHEBI:8461
FF28EJQ494
DTXSID7023518
N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine
CHEMBL643
RP-3277
60-87-7 (free base)
10H-Phenothiazine-10-ethanamine, N,N,.alpha.-trimethyl-
DTXCID803518
Phenothiazine, 10-[2-(dimethylamino)propyl]-
4-27-00-01253 (Beilstein Handbook Reference)
NSC30321
dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine
(+/-)-promethazine
NCGC00015817-05
Prometazine
Prothazine
Prometazina (INN-Spanish)
Promethazinum (INN-Latin)
Promethazine [INN:BAN]
PROMETHAZINE (MART.)
PROMETHAZINE [MART.]
PHENOTHIAZINE, 10-(2-(DIMETHYLAMINO)PROPYL)-
10-(2-DIMETHYLAMINO-2-METHYLETHYL)PHENOTHIAZINE
(+/-)-10-(2-(DIMETHYLAMINO)PROPYL)PHENOTHIAZINE
CAS-60-87-7
Dimethylamino-isopropyl-phenthiazin [German]
Promethazine (JAN/INN)
Proazamine; Diphergan; Phenargan; Phensedyl; Promazinamide
Phenergan base
SR-01000002993
38878-40-9
()-Promethazine
Remsed (Salt/Mix)
3389 R.p.
Pyrethia (Salt/Mix)
Pipolphen (Salt/Mix)
Spectrum_000868
camsilate de promAthazine
Prestwick0_000888
Prestwick1_000888
Prestwick2_000888
Prestwick3_000888
Spectrum2_000840
Spectrum3_001019
Spectrum4_001149
Spectrum5_000977
PROMETHAZINE [MI]
(.+/-.)-Promethazine
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, radical ion(1+)
PROMETHAZINE [INN]
PROMETHAZINE [JAN]
PROMETHAZINE [HSDB]
SCHEMBL4700
PROMETHAZINE [VANDF]
Lopac0_000899
Oprea1_758749
BSPBio_000676
BSPBio_002777
KBioGR_001697
KBioSS_001348
73745-50-3
DivK1c_000005
PROMETHAZINE [WHO-DD]
SPBio_000799
SPBio_002895
(Dimethylamino-2-propyl-10-phenothiazine hydrochloride
BPBio1_000744
GTPL7282
KBio1_000005
KBio2_001348
KBio2_003916
KBio2_006484
KBio3_001997
PWWVAXIEGOYWEE-UHFFFAOYSA-
D04AA10
EX-A891
N,N-DIMETHYL-1-PHENOTHIAZIN-10-YL-PROPAN-2-AMINE
R06AD02
NINDS_000005
HMS2089E08
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine hydrochloride
Tox21_110227
BDBM50017696
AKOS015962127
Tox21_110227_1
3389 RP
4182 R.p.
4182 RP
CCG-109848
DB01069
FP35119
SDCCGSBI-0050874.P005
IDI1_000005
NCGC00015817-03
NCGC00015817-04
NCGC00015817-06
NCGC00015817-08
NCGC00015817-09
NCGC00015817-10
NCGC00015817-11
NCGC00015817-12
NCGC00015817-14
NCGC00015817-17
NCGC00015817-24
NCGC00089735-02
NCGC00089735-03
AC-15939
NCI60_001878
TS-07641
SBI-0050874.P004
AB00053535
NS00010423
S5196
WLN: T C666 BN ISJ B1Y1&N1&1
C07404
D00494
EN300-708776
F17386
AB00053535-12
AB00053535_13
L000495
Q422970
10H-Phenothiazine-10-ethanamine,N,.alpha.-trimethyl-
BRD-A46335897-003-26-0
BRD-A46335897-003-27-8
N,N,-alpha-Trimethyl-10H-phenothiazine-10-ethanamine
SR-01000002993-10
N,N-Dimethyl-1-(10H-phenothiazin-10-yl)-2-propanamine
N-(2'-DIMETHYLAMINO-2-METHYL)ETHYLPHENOTHIAZINE
N,N-Dimethyl-1-(10H-phenothiazin-10-yl)-2-propanamine #
N,N,.ALPHA.-TRIMETHYL-10H-PHENOTHIAZINE-10-ETHANAMINE
10H-PHENOTHIAZINE-10-ETHANAMINE, N,N,.ALPHA.-TRIMETHYL-, (+/-)-
10H-PHENOTHIAZINE-10-ETHANAMINE, N,N,alpha-TRIMETHYL-, (+/-)-
200-489-2
InChI=1/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3
Solubility of N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine (C17H20N2S)
The solubility of N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine, commonly referenced by its chemical formula C17H20N2S, presents interesting characteristics pertinent to its usage and applications.
In understanding the solubility of this compound, consider the following points:
As with many substances, the general rule of thumb – "like dissolves like" – applies, indicating that solubility is maximized in similar types of solvents. Therefore, N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine is expected to be more soluble in non-polar or moderately polar solvents rather than in aqueous environments.
In conclusion, while detailed experimental data would offer specific solubility values, this compound generally leans towards solubility in organic solvents due to its structure and chemical properties.