Interesting facts
Interesting Facts about N,N-Diethyl-1-phenothiazin-10-yl-propan-2-amine
N,N-Diethyl-1-phenothiazin-10-yl-propan-2-amine, often referred to as a type of phenothiazine compound, holds a fascinating place in the realm of medicinal chemistry and psychopharmacology. This compound is notable for several reasons:
- Pharmaceutical Applications: Compounds like N,N-diethyl-1-phenothiazin-10-yl-propan-2-amine are integral in the development of antipsychotic medications. They work primarily by antagonizing certain neurotransmitter receptors, mainly dopamine receptors, which play a crucial role in regulating mood and behavior.
- Diverse Mechanism of Action: Phenothiazines are known for their unique ability to interact with multiple types of receptors, including adrenergic, histaminergic, and cholinergic systems, making them versatile in treating various psychological disorders.
- Side Effects and Considerations: While these compounds can be effective in treating mental health conditions, they are also associated with various side effects such as sedation and extrapyramidal symptoms. Researchers are continually investigating ways to minimize these effects while maximizing therapeutic benefits.
- Importance in Research: The study of compounds like N,N-diethyl-1-phenothiazin-10-yl-propan-2-amine aids in understanding the complex interactions between chemical substances and biological systems, making it an important subject of research in pharmacology.
- Chemical Structure Significance: The incorporation of the phenothiazine moiety, characterized by its sulfur and nitrogen-containing framework, is attributed to the compound's efficacy and behavior in biological systems, highlighting how molecular structure can influence activity.
As a chemistry student or a scientist, one can appreciate how the intricate design of compounds like N,N-diethyl-1-phenothiazin-10-yl-propan-2-amine not only contributes to the understanding of psychotropic medications but also opens avenues for developing new therapeutic agents capable of treating various disorders while reducing side effects.
In the words of Dr. Avery W. Jones, a prominent researcher in the field, "Understanding the chemical foundations of mental health medications enhances our capability to innovate and improve therapeutic interventions." This highlights the importance of continuous exploration in the field of medicinal chemistry.
Synonyms
ethopropazine
Profenamine
Parsidol
Ethopromazine
Isothazine
Isothiazine
Parsitan
522-00-9
Phenopropazine
Prophenamine
Prophenaminum
Parfezine
Parsotil
Profenamina
Profenaminum
Rodipal
Parkin
Ethapropazine
Isopthazine
Profenamina [Italian]
Fempropazine
Profenaminum [INN-Latin]
Profenamina [INN-Spanish]
2-Diethylamino-1-propyl-N-dibenzoparathiazine
10-(2-Diethylaminopropyl)phenothiazine
SKF 2538
RP 3356
SC 2538
N,N-diethyl-1-phenothiazin-10-ylpropan-2-amine
N,N-Diethyl-alpha-methyl-10H-phenothiazine-10-ethanamine
Profenamine (INN)
10-[2-(Diethylamino)propyl]phenothiazine
10-[2-(Diethylamino)-1-Propyl]phenothiazine
10H-Phenothiazine-10-ethanamine, N,N-diethyl-alpha-methyl-
10-[2-(Diethylamino)-2-methylethyl]phenothiazine
CHEMBL1206
7WI4P02YN1
10-[2-DIETHYLAMINOPROPYL]PHENOTHIAZINE
CHEBI:313639
PHENOTHIAZINE, 10-(2-(DIETHYLAMINO)PROPYL)-
diethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine
N,N-Diethyl-1-(10H-phenothiazin-10-yl)-2-propanamine
N,N-diethyl-1-(10H-phenothiazin-10-yl)propan-2-amine
Athapropazine
Athopropazin
Etopropezina
Fenpropazina
Phenoprozine
Prodierazine
Isotazin
10-(2-(Diethylamino)propyl)-phenothiazin
10H-Phenothiazine-10-ethanamine, N,N-diethyl-.alpha.-methyl-
Aethopropropazin
PROFENAMINE [INN]
W-483
Profenamine [INN:BAN]
N,N-Diethyl-.alpha.-methyl-10H-phenothiazine-10-ethanamine
Phenothiazine, 10-[2-(diethylamino)propyl]-
10-(2-(DIETHYLAMINO)PROPYL)PHENOTHIAZINE
W 483
EINECS 208-320-4
UNII-7WI4P02YN1
SR-05000001626
Dibutil (Salt/Mix)
Lysivane (Salt/Mix)
Pardisol (Salt/Mix)
Spectrum_000815
Parphezein (Salt/Mix)
Prodictazin (Salt/Mix)
Prestwick0_000840
Prestwick1_000840
Prestwick2_000840
Prestwick3_000840
Spectrum2_000984
Spectrum3_000429
Spectrum4_000548
Spectrum5_001592
(.+/-.)-Profenamine
ETHOPROPAZINE [MI]
NCIOpen2_008174
SCHEMBL34045
(+/-)-PROFENAMINE
BSPBio_000799
BSPBio_002018
ETHOPROPAZINE [VANDF]
KBioGR_001215
KBioSS_001295
PROFENAMINE [WHO-DD]
DivK1c_000061
(+/-)-ETHOPROPAZINE
SPBio_001047
SPBio_002720
BDBM8958
BPBio1_000879
GTPL7181
DTXSID2023018
KBio1_000061
KBio2_001295
KBio2_003863
KBio2_006431
KBio3_001238
NINDS_000061
AKOS040753613
DB00392
RP-3356
SC-2538
SDCCGSBI-0051378.P004
IDI1_000061
NCGC00178860-03
NCGC00178860-10
SBI-0051378.P003
phenothiazine, 10-(2-diethylaminopropyl)-
AB00053474
NS00006829
D08426
AB00053474_04
EN300-18530982
L001334
N,N-diethyl-1-phe-nothiazin-10-yl-propan-2-amine
Q7247908
SR-05000001626-4
BRD-A16311756-003-01-0
BRD-A16311756-003-08-5
BRD-A16311756-003-09-3
N,N-Diethyl-1-(10H-phenothiazin-10-yl)-2-propanamine #
Solubility of N,N-Diethyl-1-phenothiazin-10-yl-propan-2-amine
The solubility of N,N-diethyl-1-phenothiazin-10-yl-propan-2-amine (C19H24N2S) can be influenced by several factors, primarily due to its structural characteristics. Here are some key points to consider:
It is essential to conduct empirical solubility tests to better understand the specific solubility behavior of this compound under different conditions. As a rule of thumb, the presence of the phenothiazine ring often leads to limited solubility in aqueous environments, which can be mathematically estimated using Hansen solubility parameters.
Conclusion
In summary, the solubility of C19H24N2S is paramount for its applications and should be comprehensively investigated to predict its behavior in various chemical environments.