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Dibenzylchloroethanolamine hydrochloride

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Identification
Molecular formula
C16H19Cl2N
CAS number
5069-56-1
IUPAC name
N,N-dibenzyl-2-chloro-ethanamine;hydrochloride
State
State

At room temperature, Dibenzylchloroethanolamine hydrochloride is a solid compound. It should be handled with care as it may react with water or moisture to form hydrochloric acid.

Melting point (Celsius)
108.00
Melting point (Kelvin)
381.15
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
291.23g/mol
Molar mass
291.2200g/mol
Density
1.1473g/cm3
Appearence

Dibenzylchloroethanolamine hydrochloride typically appears as a white to off-white crystalline powder. The compound is usually stable under standard conditions and should be protected from moisture due to its hygroscopic nature.

Comment on solubility

Solubility of N,N-dibenzyl-2-chloro-ethanamine;hydrochloride (C16H19Cl2N)

N,N-dibenzyl-2-chloro-ethanamine;hydrochloride typically exhibits varied solubility characteristics, largely influenced by its ionic nature. As a salt form, this compound is expected to show different solubility behaviors compared to its free base counterpart. Here are some key considerations regarding its solubility:

  • Water Solubility: The presence of the hydrochloride indicates that it is soluble in water. This is typical for many amine hydrochlorides due to the ability of water to stabilize the charged species.
  • Organic Solvents: N,N-dibenzyl-2-chloro-ethanamine;hydrochloride may have limited solubility in non-polar organic solvents due to its polar characteristics.
  • Temperature Influence: Like many salts, solubility may increase with temperature, which can be useful in various applications and formulations.
  • pH Dependence: Changes in pH can influence the solubility of the compound; generally, an increase in pH could cause deprotonation and lead to decreased solubility in aqueous solutions.

In summary, solubility is an important aspect to consider in the context of N,N-dibenzyl-2-chloro-ethanamine;hydrochloride, affecting not only its handling and application but also its pharmacological properties. Understanding these factors is essential for effective use in both laboratory and industrial settings.

Interesting facts

Interesting Facts about N,N-Dibenzyl-2-chloro-ethanamine; Hydrochloride

N,N-Dibenzyl-2-chloro-ethanamine; hydrochloride is a fascinating compound in the realm of organic chemistry and pharmacology. Here are some key aspects to consider:

  • Pharmaceutical Relevance: This compound is often investigated for its potential use in the development of therapeutic agents. Its structural features allow for interactions with various biological targets, making it a point of interest in drug design.
  • Synthesis Techniques: The synthesis typically involves the reaction of benzyl chloride with 2-aminoethanol in the presence of a suitable catalyst. This showcases the application of nucleophilic substitution reactions in organic chemistry.
  • Chlorine Atom Significance: The presence of the chlorine atom in the ethylamine part of the molecule can influence its reactivity and biological activity, altering the compound's properties significantly.
  • Applications in Research: Scientists are keen on exploring this compound's role in understanding neuropharmacology due to its structural similarity to certain neurotransmitters. This similarity may yield insights into receptor interactions.
  • Complex Interactions: As a quaternary ammonium compound, this hydrochloride salt has interesting solubility and ionization characteristics that can affect its biological availability and transport in different systems.

In conclusion, the study of N,N-dibenzyl-2-chloro-ethanamine; hydrochloride not only highlights the intricate nature of organic compounds but also emphasizes the continuous potential for innovation and discovery in medicinal chemistry. As an aspiring chemist or student, understanding such compounds opens doors to future research and development in effective therapeutic agents.

Synonyms
55-43-6
N-(2-Chloroethyl)dibenzylamine hydrochloride
Dibenamine hydrochloride
N,N-dibenzyl-2-chloroethanamine hydrochloride
Sympatholytin
Dibenzylchlorethamine hydrochloride
Dibenamine HCl
N,N-Dibenzyl-2-chloroethylamine hydrochloride
Dibenzylchlorethylamine hydrochloride
N,N-Dibenzylaminoethyl chloride hydrochloride
N,N-dibenzyl-2-chloroethanamine;hydrochloride
2-Chloroethyldibenzylamine hydrochloride
N-(2-CHLOROETHYL)DIBENZYLAMINE HCl
2-Dibenzylaminoethyl chloride hydrochloride
EINECS 200-234-5
NSC 11491
Dibenzyl(2-chloroethyl)ammonium chloride
beta-Chloroethyldibenzylamine hydrochloride
Benzenemethanamine, N-(2-chloroethyl)-N-(phenylmethyl)-, hydrochloride
DIBENZYLAMINE, N-(2-CHLOROETHYL)-, HYDROCHLORIDE
N,N-Dibenzyl-beta-chloroethylamine hydrochloride
NSC-11491
Dibenamine (hydrochloride)
W65S0F7870
(2-Chloroethyl)dibenzylamine hydrochloride
DTXSID3075337
N,N-Dibenzyl-.beta.-chloroethylamine hydrochloride
DIBENAMINE HYDROCHLORIDE [MI]
DIBENAMINE HYDROCHLORIDE [WHO-DD]
dibenzyl(2-chloroethyl)amine hydrochloride
MFCD00012518
2-(DIBENZYLAMINO)ETHYL CHLORIDE HYDROCHLORIDE
(.BETA.-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
(N,N-DIBENZYLAMINO)ETHYL CHLORIDE HYDROCHLORIDE
N-(2-Chloroethyl)Dibenzylamine (Hydrochloride)
UNII-W65S0F7870
N,N'-Dibenzyl-2-chloroethylamine hydrochloride
SCHEMBL334991
CHEMBL3272451
DTXCID8041820
WLN: G2N1R&1R &GH
NSC11491
s5432
AKOS005267134
CCG-267427
N-(chloroethy)dibenzylamine hydrochloride
AS-66599
SY112039
DB-052731
dibenzyl-(2-chloroethyl)amine hydrochloride
HY-128380
.beta.-Chloroethyldibenzylamine hydrochloride
CS-0099460
2-chloro-N,N-dibenzylethanamine hydrochloride
N-(2-Chloroethyl) dibenzylamine hydrochloride
N-(2-hloroethyl)ibenzylamine (Hydrochloride)
D78410
(BETA-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
N-(2-Chloroethyl)dibenzylamine hydrochloride, 98%
Q27292380
Benzenemethanamine, N-(2-chloroethyl)-N-(phenylmethyl)-, hydrochloride (9CI)