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Dibenzylchloroethylamine

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Identification
Molecular formula
C16H18ClN
CAS number
27478-71-7
IUPAC name
N,N-dibenzyl-2-chloro-ethanamine
State
State

At room temperature, Dibenzylchloroethylamine is typically found as a liquid.

Melting point (Celsius)
-5.00
Melting point (Kelvin)
268.15
Boiling point (Celsius)
345.00
Boiling point (Kelvin)
618.15
General information
Molecular weight
259.78g/mol
Molar mass
259.7810g/mol
Density
1.0675g/cm3
Appearence

Dibenzylchloroethylamine is typically a clear to slightly yellow liquid. It may exhibit a slight aromatic odor due to its benzyl groups.

Comment on solubility

Solubility of N,N-dibenzyl-2-chloro-ethanamine

N,N-dibenzyl-2-chloro-ethanamine, with the chemical formula C16H18ClN, exhibits unique solubility characteristics that are influenced by its molecular structure. This compound is generally categorized as a polar organic molecule due to the presence of the amino group and the chlorine atom. Consequently, its solubility can be summarized as follows:

  • Solubility in Water: N,N-dibenzyl-2-chloro-ethanamine is expected to have limited solubility in water. The hydrophobic nature of the benzyl groups tends to hinder strong hydrogen bonding with water molecules.
  • Solubility in Organic Solvents: This compound is likely to be soluble in many organic solvents, such as ethanol, methanol, and acetone, due to its non-polar characteristics from the benzyl groups.
  • Temperature Dependence: The solubility may increase with temperature, as higher temperatures can enhance molecular motion and interaction with solvents.

In summary, while N,N-dibenzyl-2-chloro-ethanamine may not be highly soluble in water, its compatibility with various organic solvents allows for flexibility in applications. This solubility behavior is pivotal for its use in synthesis and chemical reactions. As a reminder, always consider the specific solvent properties when exploring solubility!

Interesting facts

Interesting Facts About N,N-Dibenzyl-2-chloro-ethanamine

N,N-dibenzyl-2-chloro-ethanamine is an intriguing chemical compound with a variety of applications in organic synthesis and medicinal chemistry. Here are some interesting insights into this compound:

  • Structural Uniqueness: The compound features two benzyl groups attached to a nitrogen atom, which can significantly influence its chemical properties and reactivity. This structural arrangement makes it a versatile building block in organic reactions.
  • Role in Synthesis: N,N-dibenzyl-2-chloro-ethanamine can serve as an important intermediate in the synthesis of various pharmaceutical agents. Its ability to undergo nucleophilic substitution reactions facilitates the formation of complex molecular structures.
  • Chirality Potential: The presence of a single chiral center in the molecule offers potential for the development of enantiomerically pure compounds. This is particularly valuable in the pharmaceutical industry, where the activity of a drug can depend heavily on its chirality.
  • Biological Relevance: Research has indicated that compounds similar to N,N-dibenzyl-2-chloro-ethanamine may exhibit various biological activities, making it a subject of interest in medicinal chemistry. Understanding its interactions can lead to the development of new therapeutic agents.
  • Synthetic Pathways: The synthesis of this compound often involves straightforward methods such as the reaction of benzylamine with chloroacetyl chloride, demonstrating its accessibility for research and industrial chemistry.

In summary, N,N-dibenzyl-2-chloro-ethanamine is not only significant in terms of its chemical properties but also in its potential applications across various fields, including organic synthesis and pharmacology. As chemistry continues to evolve, compounds like this one remind us of the interconnectedness of molecular structure and function.

Synonyms
DIBENAMINE
51-50-3
Dibenzylchlorethamine
Sympatholytin
N,N-Dibenzyl-2-chloroethanamine
Dibenzyl chlorethylamine
N-(2-Chloroethyl)dibenzylamine
2-(Dibenzylamino)ethyl chloride
Dibenzylchlorethylamine
Dibenzyl(2-chloroethyl)amine
2-Chloroethyldibenzylamine
Dibenzyl-2-chloroethylamine
Dibenzylamine, N-(2-chloroethyl)-
N,N-Dibenzyl-2-chloroethylamine
HSDB 2086
SKF 199
N,N-Dibenzyl-beta-chloroethylamine
BRN 2213696
DIBENAMINE [MI]
DIBENAMINE [HSDB]
N,N-Dibenzyl-.beta.-chloroethylamine
N-(2-Chloroethyl)-N-(phenylmethyl)benzenemethanamine
43EXU2S56H
DTXSID20199001
4-12-00-02180 (Beilstein Handbook Reference)
N,N-DIBENZYLAMINOETHYL CHLORIDE
N,N-dibenzyl-N-(2-chloroethyl)amine
Chlorethylamine, Dibenzyl
UNII-43EXU2S56H
Benzenemethanamine, N-(2-chloroethyl)-N-(phenylmethyl)-
2-chloro-N,N-bis(phenylmethyl)ethanamine
SCHEMBL479112
1-dibenzylamino-2-chloroethane
CHEMBL3305685
BDBM81445
dibenzyl-(2-chloro-ethyl)-amine
GTPL13154
DTXCID10121492
N,N-Dibenzyl-2-chloroethanamine #
NSC_5820
BBL028457
PDSP1_001100
PDSP2_001084
STK526670
AKOS005459848
CAS_55-43-6
AA-516/31407024
AE-848/01428028
SR-01000883996
SR-01000883996-1
Q27258645