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Pramipexole

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Identification
Molecular formula
C10H17N3S
CAS number
104632-26-0
IUPAC name
N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
State
State

At room temperature, Pramipexole exists as a solid in the form of a crystalline powder.

Melting point (Celsius)
296.60
Melting point (Kelvin)
569.80
Boiling point (Celsius)
470.15
Boiling point (Kelvin)
743.30
General information
Molecular weight
302.43g/mol
Molar mass
302.4270g/mol
Density
1.1390g/cm3
Appearence

Pramipexole is typically a white or off-white crystalline powder. It is practically insoluble in water and soluble in dimethyl sulfoxide.

Comment on solubility

Solubility of N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine

The solubility of N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine (C10H17N3S) can be influenced by its chemical structure and functional groups. Here are some key points regarding its solubility:

  • Polar Nature: The presence of the amine and thiazole groups suggests some level of polarity, which may enhance solubility in polar solvents.
  • Efficient Dissolution: Compounds like this may dissolve better in protic solvents, such as water, methanol, or ethanol, due to the potential for hydrogen bonding.
  • Non-Polar Solvents: Conversely, the propyl group may contribute to some solubility in non-polar solvents, but it's generally expected to be less effective.
  • Temperature Effects: Solubility can also vary with temperature; increased temperatures typically increase solubility for many compounds.

In conclusion, while N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine is expected to demonstrate moderate solubility in polar solvents, it may exhibit limited solubility in non-polar solvents. Overall, the solubility characteristic is critical for applications such as drug formulation and biological activity.

Interesting facts

Interesting Facts about N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine

N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine is a fascinating compound that has captured the interest of many in the fields of chemistry and pharmacology.

Key Features

  • Structure: This compound features a unique benzothiazole ring fused with a saturated tetrahydro moiety, which significantly influences its chemical behavior and potential applications.
  • Potential Biological Activity: The amine and thiazole functionalities suggest that it could interact with various biological targets, making it a candidate for further studies in medicinal chemistry.
  • Versatile Synthesis: Chemists have developed multiple synthetic pathways to create this compound, showcasing the flexibility in its synthesis and how variations can yield diverse derivatives.

Research Insights

Research on compounds similar to N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine has indicated potential roles in:

  • Antimicrobial properties: Investigating how the compound affects microbial growth.
  • Neuroprotective effects: Analyzing its impacts on neurodegenerative disorders.
  • Cancer research: Exploring its potential to inhibit tumor growth.

Final Thoughts

This compound serves as a prime example of how intricate chemical structures can lead to significant biological implications. As scientists continue to explore its properties, N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine may pave the way for future discoveries in drug development and therapeutic applications. The combination of its unique structure and potential biological activity makes it an exciting topic of study in current scientific research.

Synonyms
104617-86-9
N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
(+/-)-Pramipexole
6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
N6-Propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
CHEMBL76399
(S)-N6-Propyl-4,5,6,7-tetrahydrobenzothiazole-2,6-diamine
SND 919
MFCD00869076
Pramipexole Base
()-Pramipexole
(R)-Pramipexole;R-(+)-Pramipexole;KNS-760704
SCHEMBL195775
DTXSID9091527
DTXSID90274450
CHEBI:182913
HMS3370D06
HMS3393A21
HMS3657G15
(S)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzthiazole;(S)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzthiazole
ALBB-027263
HHC23009
BDBM50017550
AKOS017258887
SB16953
SY009549
NS00121232
EN300-296092
L000492
2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole
N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine
(+/-) 2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole
(+/-)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole
(+/-)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzthiazole
(+/-)2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole
(S)-2-Amnio-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole
(+/-)-2-amino-6-(N-propylamino)-4,5,6,7-tetrahydrobenzothiazole
2,6-benzothiazolediamine, 4,5,6,7-tetrahydro-N~6~-propyl-, dihydrochloride
N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine (Pramipexole, PPX)