Interesting facts
Interesting Facts about N,5-bis(4-chlorophenyl)-3-isopropylimino-phenazin-2-amine
N,5-bis(4-chlorophenyl)-3-isopropylimino-phenazin-2-amine is a compound that showcases intriguing features within the realm of organic chemistry. Here are some key points to consider:
- Chemical Structure: This compound possesses a complex aromatic structure, including phenazine moieties, which contribute to its stability and electronic properties.
- Biological Activity: Phenazine derivatives, like this one, are known for their biological significance. They exhibit a range of activities, including antimicrobial and antitumor properties. This makes compounds in this class of great interest for medicinal chemistry.
- Chlorine Substitution: The presence of chlorine atoms in the chemical structure often enhances the reactivity of the compound, potentially leading to interesting chemical transformations. Chlorinated compounds can also have unique properties, such as improved lipophilicity.
- Imine Functionality: The imino group in the molecule introduces a site of reactivity that can be leveraged for further synthetic modifications. This can open pathways to develop new derivatives with tailored properties.
- Applications in Dyes: Compounds with phenazine cores are not just limited to biological applications; they are also used in dye production. Their vibrant colors and stability make them suitable for various industries, including textiles and plastics.
In summary, N,5-bis(4-chlorophenyl)-3-isopropylimino-phenazin-2-amine presents a fascinating subject for exploration within organic and medicinal chemistry. Its versatile chemical properties could lead to numerous practical applications, making it a compound of significant interest to scientists and researchers alike.
Synonyms
clofazimine
2030-63-9
Lamprene
Chlofazimine
Lampren
Clofazimina
Clofaziminum
B 663 (Pharmaceutical)
Clofaziminum [INN-Latin]
Clofazimina [INN-Spanish]
NSC-141046
N,5-bis(4-chlorophenyl)-3-propan-2-yliminophenazin-2-amine
G 30320
B-663
3-(p-Chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin
3-(p-Chloroanilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)phenazine
B 663
3-(p-Chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazine
MFCD00056793
G-30320
D959AE5USF
CHEMBL1083384
DTXSID7022839
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(isopropylimino)phenazin-2-amine
2-Phenazinamine, 3,5-dihydro-N,5-bis(4-chlorophenyl)-3-((1-methylethyl)imino)-
2-Phenazinamine, N,5-bis(4-chlorophenyl)-3,5-dihydro-3-((1-methylethyl)imino)-
2-Phenazinamine, N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-2-phenazinamine
MMV687800
NSC141046
Phenazine, 2,10-dihydro-3-(p-chloroanilino)-10-(p-chlorophenyl)-2-(isopropylimino)-
Phenazine, 3-(p-chloroanilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-
NCGC00016600-01
CAS-2030-63-9
N,5-bis(4-chlorophenyl)-3-(propan-2-ylimino)-3,5-dihydrophenazin-2-amine
3-(p-Chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)phenazine
Riminophenazine
N,5-bis(4-chlorophenyl)-3-(isopropylimino)-3,5-dihydrophenazin-2-amine
B 663 (VAN)
(3Z)-N,5-bis(4-chlorophenyl)-3-[(1-methylethyl)imino]-3,5-dihydrophenazin-2-amine
Lamprene (TN)
SMR000058704
B 663, pharmaceutical
SR-05000001807
EINECS 217-980-2
UNII-D959AE5USF
NSC 141046
BRN 0060420
Colfazimine
Clofazimine (JAN/USP/INN)
(3E)-N,5-bis(4-chlorophenyl)-3-isopropylimino-phenazin-2-amine
Clofazimine [USAN:USP:INN:BAN]
Prestwick_685
3-(p-Chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin [German]
SMP2_000339
Clofazimine (Standard)
B663
CPD000058704
CLOFAZIMINE [MI]
Prestwick0_000376
Prestwick1_000376
Prestwick2_000376
Prestwick3_000376
CLOFAZIMINE [INN]
CLOFAZIMINE [JAN]
CLOFAZIMINE [USAN]
B. 663
CLOFAZIMINE [VANDF]
COLFAZIMINE [VANDF]
cid_2794
CHEMBL1292
CLOFAZIMINE [MART.]
BIDD:PXR0147
SCHEMBL26757
SCHEMBL26758
BSPBio_000531
CLOFAZIMINE [USP-RS]
CLOFAZIMINE [WHO-DD]
CLOFAZIMINE [WHO-IP]
4-25-00-03033 (Beilstein Handbook Reference)
MLS000028617
MLS001424318
MLS006010789
SPBio_002452
BPBio1_000585
CHEBI:3749
DTXCID302839
GTPL9184
SCHEMBL5663361
HY-B1046R
CLOFAZIMINE [ORANGE BOOK]
WDQPAMHFFCXSNU-KRUMMXJUSA-N
WDQPAMHFFCXSNU-UHFFFAOYSA-N
CLOFAZIMINE [EP MONOGRAPH]
CLOFAZIMINE [USP IMPURITY]
HMS1569K13
HMS2052B05
HMS2093J10
HMS2096K13
HMS2231B04
HMS3370N05
HMS3394B05
HMS3652A16
HMS3713K13
KUC109573N
Pharmakon1600-01505974
CLOFAZIMINE [USP MONOGRAPH]
BCP07792
CLOFAZIMINUM [WHO-IP LATIN]
HY-B1046
KSC-27-052A
Tox21_110516
BDBM50318909
BDBM50378783
NSC759283
s4107
AKOS015896438
AKOS026749881
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(isopropyliaino)phenazin-2-amine
AC20496
CCG-101159
CCG-269477
CS-4567
DB00845
KS-1412
NC00409
NSC-759283
2-Phenazinamine,N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-
NCGC00016600-02
NCGC00016600-03
NCGC00016600-04
NCGC00016600-05
NCGC00016600-07
NCGC00016600-08
NCGC00016600-09
NCGC00179529-01
DA-72278
SMR004701474
Clofazimine 100 microg/mL in Acetonitrile
Phenazine,10-dihydro-2-(isopropylimino)-
SBI-0206865.P001
C2866
NS00011720
SW196840-4
C06915
D00278
EN300-267815
EN300-21680301
Q418611
SR-01000000259
SR-01000000259-6
SR-05000001807-1
SR-05000001807-2
BRD-K56614220-001-10-9
BRD-K56614220-001-18-2
BRD-K56614220-001-19-0
BRD-K56614220-001-21-6
Z2037279473
Clofazimine, European Pharmacopoeia (EP) Reference Standard
Clofazimine, United States Pharmacopeia (USP) Reference Standard
2-p-Chloranilino-5-p-chlorphenyl-3,5-dihydro-3-isopropylimino-phenazin
(3E)-N,5-bis(4-chlorophenyl)-3-[(propan-2-yl)imino]-3,5-dihydrophenazin-2-amine
(4-Chloro-phenyl)-[5-(4-chloro-phenyl)-3-isopropylimino-3,5-dihydro-phenazin-2-yl]-amine
(E)-N,5-bis(4-chlorophenyl)-3-(isopropylimino)-3,5-dihydrophenazin-2-amine
2-Phenazinamine,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-
2-Phenazinamine,5-dihydro-N,5-bis(4-chlorophenyl)-3-[(1-methylethyl)imino]-
Clofazimine for system suitability, European Pharmacopoeia (EP) Reference Standard
N,5-Bis(4-chlorophenyl)-3-([1-methylethyl]imino)-3,5-dihydro-2-phenazinamine #
N,5-bis(4-chlorophenyl)-3-[(propan-2-yl)imino]-3,5-dihydrophenazin-2-amine
Phenazine,10-dihydro-3-(p-chloroanilino)-10-(p-chlorophenyl)-2-(isopropylimino)-
2458811-14-6
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-2-phenazina mine;3-(p-Chloroanilino)-10-(p-chlorophenyl)-2,10-dihydro-2- (isopropylimino)phenazine
Solubility of N,5-bis(4-chlorophenyl)-3-isopropylimino-phenazin-2-amine (C27H19Cl2N3)
The solubility of N,5-bis(4-chlorophenyl)-3-isopropylimino-phenazin-2-amine in various solvents can be characterized by several key factors:
As a rule of thumb, compounds with higher molecular weights and complex structures like N,5-bis(4-chlorophenyl)-3-isopropylimino-phenazin-2-amine tend to exhibit lower solubility in aqueous solutions. Consequently, understanding the solubility profile is crucial for applications in pharmaceuticals and materials science.
In summary, the solubility of this compound highlights the intricate relationship between molecular structure and its solvation dynamics, revealing the balance between hydrophobic and hydrophilic interactions.