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BIRT-377

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Identification
Molecular formula
C34H32N10O2
CAS number
343787-29-1
IUPAC name
N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-ylamino)phenyl]terephthalamide
State
State

At room temperature, BIRT-377 is in a solid state.

Melting point (Celsius)
320.00
Melting point (Kelvin)
593.15
Boiling point (Celsius)
550.00
Boiling point (Kelvin)
823.15
General information
Molecular weight
641.74g/mol
Molar mass
641.7400g/mol
Density
1.3600g/cm3
Appearence

BIRT-377 typically appears as a pale yellow solid powder.

Comment on solubility

Solubility of N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-ylamino)phenyl]terephthalamide

N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-ylamino)phenyl]terephthalamide exhibits unique solubility characteristics that can be summarized as follows:

  • Solvent Dependence: The solubility of this compound is significantly influenced by the choice of solvent. It tends to dissolve better in polar solvents compared to non-polar ones.
  • pH Influence: The solubility is also pH-dependent; increased solubility is observed in alkaline conditions due to potential ionization of the amine groups present in the molecule.
  • Temperature Effects: Higher temperatures can enhance the solubility of this compound, as increased kinetic energy helps the molecules overcome solvation barriers.
  • Polymeric Interaction: In the presence of certain polymers, the solubility can either be enhanced or hindered, depending on the nature of the polymer and its interaction with the compound.

In summary, while this compound may not be highly soluble across all solvents, its solubility profile demonstrates a fascinating interplay between solvent polarity, pH levels, and temperature variations. This complex behavior underscores the importance of considering various conditions when assessing the solubility of chemical compounds.

Interesting facts

Interesting Facts about N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-ylamino)phenyl]terephthalamide

N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-ylamino)phenyl]terephthalamide is a fascinating compound that plays a significant role in the field of medicinal chemistry. Here are some intriguing aspects:

  • Bioactivity: This compound possesses potential bioactive properties that may contribute to its relevance in drug development. Its structure allows for interactions with biological targets, making it a candidate for further pharmacological studies.
  • Synthesis: The synthetic pathways leading to this compound often involve multi-step reactions that require careful conditions and reagents, showcasing the complexity and beauty of organic synthesis.
  • Therapeutic Applications: Research indicates possibilities in treating various diseases due to its imidazole moiety, which is known to be linked with various pharmacological activities such as antifungal, antibacterial, and anticancer effects.
  • Structure-Activity Relationship: The relationship between its chemical structure and biological activity can provide insights into optimizing drug design, particularly in the development of agents with improved efficacy and reduced toxicity.
  • Potential in Materials Science: Beyond medicinal applications, this compound could have interesting properties in materials science, particularly in developing advanced polymers or nanocomposites.

In conclusion, N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2-ylamino)phenyl]terephthalamide not only exemplifies the intricate world of organic compounds but also highlights the interconnectedness of chemistry in addressing health and material challenges. As research continues, its full potential may yet be unveiled, paving the way for innovative solutions in various fields.

Synonyms
Terephthalanilide, 4',4''-bis(2-imidazolin-2-ylamino)-
64QR71LB83
537-66-6
4',4''-Bis(imidazolin-2-yl-amino)terephthalanilide
GNF-Pf-4940
BRN 0968373
UNII-64QR71LB83
4',4''-Bis(2-imidazolin-2-yl-amino)terephthalanilide
CHEMBL525140
SCHEMBL25605204
DTXSID20862147
5-25-09-00309 (Beilstein Handbook Reference)
N,N'-BIS(4-((4,5-DIHYDRO-1H-IMIDAZOL-2-YL)AMINO)PHENYL)-1,4-BENZENEDICARBOXAMIDE
N,Na(2)-Bis[4-[(4,5-dihydro-1H-imidazol-2-yl)amino]phenyl]-1,4-benzenedicarboxamide
1,4-BENZENEDICARBOXAMIDE, N,N'-BIS(4-((4,5-DIHYDRO-1H-IMIDAZOL-2-YL)AMINO)PHENYL)-
1,4-BENZENEDICARBOXAMIDE, N1,N4-BIS(4-((4,5-DIHYDRO-1H-IMIDAZOL-2-YL)AMINO)PHENYL)-