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Acetanilide

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Identification
Molecular formula
C9H11NO
CAS number
103-89-9
IUPAC name
N-(p-tolyl)acetamide
State
State
At room temperature, acetanilide is in a solid state as it forms crystalline flakes or a powder.
Melting point (Celsius)
113.50
Melting point (Kelvin)
386.60
Boiling point (Celsius)
304.00
Boiling point (Kelvin)
577.00
General information
Molecular weight
135.17g/mol
Molar mass
135.1670g/mol
Density
1.0773g/cm3
Appearence

Acetanilide appears as colorless, white, or off-white crystalline solid flakes or powder. It is odorless but has a slightly sweet taste. The compound is typically presents in a refined state without impurities.

Comment on solubility

Solubility of N-(p-tolyl)acetamide

N-(p-tolyl)acetamide, a chemical compound with the formula C10H13NO, exhibits interesting solubility characteristics that are essential for its applications in various fields.

General Solubility

This compound is moderately soluble in a variety of solvents, making it versatile in different chemical environments. Notably:

  • Water: N-(p-tolyl)acetamide demonstrates limited solubility in water due to its organic nature and hydrophobic p-tolyl group.
  • Organic Solvents: It is more soluble in common organic solvents such as ethanol and acetone, which can effectively dissolve this compound.

Factors Affecting Solubility

The solubility of N-(p-tolyl)acetamide can be influenced by various factors:

  • Temperature: Higher temperatures generally increase solubility in both water and organic solvents.
  • Presence of Solvents: The choice of solvent significantly affects solubility; polar solvents enhance solubility compared to non-polar solvents.
  • Concentration: The concentration of the compound can also alter solubility, often leading to saturation in certain solvents.

In conclusion, while N-(p-tolyl)acetamide has limited solubility in water, its greater affinity for organic solvents opens avenues for its use in a variety of chemical reactions and formulations. Understanding these solubility properties is critical for scientists and engineers working with this compound.

Interesting facts

Interesting Facts About N-(p-tolyl)acetamide

N-(p-tolyl)acetamide, also known as p-toluidine acetamide, is a fascinating organic compound with a range of applications in the scientific and industrial realms. Below are some intriguing aspects of this compound:

  • Synthesized with Care: N-(p-tolyl)acetamide is synthesized through a reaction between p-toluidine and acetic anhydride or acetic acid. This process highlights the importance of understanding reaction mechanisms and the impact of functional groups in organic synthesis.
  • Biological Relevance: This compound has garnered attention in the field of medicinal chemistry. Its derivatives are being explored for potential use in pharmaceutical formulations, showcasing the significance of amides in drug design.
  • Versatility in Applications: Beyond pharmaceuticals, N-(p-tolyl)acetamide is utilized in the production of dyes and pigments, demonstrating its versatility in various chemical applications.
  • Research and Development: As researchers continue to synthesize and study derivatives of N-(p-tolyl)acetamide, numerous possibilities for innovation and new applications in materials science and organic chemistry arise.
  • Analytical Importance: The study of N-(p-tolyl)acetamide and its derivatives often employs techniques such as NMR and IR spectroscopy, emphasizing the importance of analytical chemistry in understanding molecular structure and behavior.

In summary, N-(p-tolyl)acetamide is more than just a simple organic molecule. It has potential implications in fields from pharmaceuticals to dye manufacturing. As we continue to explore its properties and applications, this compound serves as a reminder of the intricate connections between chemistry and everyday life.

Synonyms
4'-Methylacetanilide
103-89-9
N-(4-Methylphenyl)acetamide
4-Methylacetanilide
p-Acetotoluidide
P-Acetotoluide
N-ACETYL-P-TOLUIDINE
4-Acetotoluide
Acetyl-p-toluidine
Acetamide, N-(4-methylphenyl)-
p-Acetamidotoluene
p-Methylacetanilide
p-Acetotoluidine
1-Acetamido-4-methylbenzene
N-Acetyl-p-toluidide
4-(Acetylamino)toluene
4-Acetotoluidide
N-Acetoxy-4-toluidine
N-p-tolylacetamide
NSC 7644
CCRIS 5956
EINECS 203-155-4
MFCD00008677
N36D4JN82T
DTXSID6024414
AI3-01428
NSC-7644
ACETAMIDOTOLUENE, P-
P-ACETOTOLUIDE [MI]
DTXCID104414
ACETYL-P-TOLUIDINE, N-
N-(p-tolyl)acetamide
4-ACETAMIDOTOLUENE
UNII-N36D4JN82T
Acet-p-toluidide
P-TOLYACETAMIDE
4\'-Methylacetanilide
N-(p-tolyl)-acetamide
P-ACETYLAMINOTOLUENE
SCHEMBL61417
WLN: 1VMR D1
4'-Methylacetanilide, 99%
MLS002415754
n-(4-methyl-phenyl)acetamide
N-ACETYL-PARA-TOLUIDINE
CHEMBL1604472
N-ACETYL-4-METHYLANILINE
SCHEMBL12309457
YICAMJWHIUMFDI-UHFFFAOYSA-
NSC7644
CHEBI:143108
HMS3039J04
Tox21_200119
STL163784
AKOS000120002
BS-3827
NCGC00091129-01
NCGC00091129-02
NCGC00257673-01
CAS-103-89-9
SMR001370915
SY035719
DB-014506
A0064
CS-0063380
NS00023266
4 inverted exclamation mark -Methylacetanilide
EN300-15544
AH-034/32844007
Q27284480
Z28134680
F1962-0207
InChI=1/C9H11NO/c1-7-3-5-9(6-4-7)10-8(2)11/h3-6H,1-2H3,(H,10,11)