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Nicotinamide adenine dinucleotide

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Identification
Molecular formula
C11H12N2O2
CAS number
10033-23-1
IUPAC name
N-methyl-4-oxo-4-(3-pyridyl)butanamide
State
State

At room temperature, it exists typically as a white to off-white crystalline solid, characterized by its distinct structural features and stability under standard conditions.

Melting point (Celsius)
112.00
Melting point (Kelvin)
385.15
Boiling point (Celsius)
296.00
Boiling point (Kelvin)
569.15
General information
Molecular weight
192.22g/mol
Molar mass
192.2180g/mol
Density
0.7500g/cm3
Appearence

N-methyl-4-oxo-4-(3-pyridyl)butanamide, also commonly known as a derivative used in nicotinamide research, often appears as a crystalline solid or powder. The color may vary from white to off-white, depending on purity and formulation.

Comment on solubility

Solubility of N-methyl-4-oxo-4-(3-pyridyl)butanamide

N-methyl-4-oxo-4-(3-pyridyl)butanamide, with the chemical formula C11H12N2O2, presents intriguing solubility characteristics. This compound's solubility profile can be attributed to its molecular structure and functional groups, which influence how it interacts with various solvents.


Key solubility points:

  • Polar vs Nonpolar Solvents: The presence of the amide group (-C(=O)NH-) suggests that the compound may exhibit greater solubility in polar solvents, such as water, compared to nonpolar solvents.
  • Hydrogen Bonding: The amide functional group allows for the formation of hydrogen bonds, which can enhance solubility in protic solvents.
  • pH Dependency: Solubility can also vary with pH; the presence of the pyridine ring may affect the ionization state and consequently the solubility in aqueous environments.
  • Temperature Effects: Like many organic compounds, solubility may increase with temperature, making it more soluble at elevated temperatures.

In summary, while N-methyl-4-oxo-4-(3-pyridyl)butanamide is expected to be soluble in polar solvents due to its amide and pyridine functionalities, the exact solubility can vary based on the solvent type and environmental conditions. It's important to conduct empirical solubility tests for precise applications.

Interesting facts

Interesting Facts about N-methyl-4-oxo-4-(3-pyridyl)butanamide

N-methyl-4-oxo-4-(3-pyridyl)butanamide is a fascinating compound with numerous intriguing attributes. This organic molecule is a member of the amide family and features both a pyridine ring and carbonyl group, which makes it noteworthy in various chemical contexts. Here are some key points to consider:

  • Biological Relevance: Compounds featuring amide groups are prevalent in medicinal chemistry. Many drugs are designed around the amide functional group due to their ability to form hydrogen bonds, which enhances bioactivity.
  • Pyridine Moiety: The presence of the 3-pyridyl group in this compound contributes to its electronic properties, making it a potential candidate for developing novel pharmaceuticals, particularly in the treatment of diseases related to the central nervous system.
  • Synthetic Versatility: This compound can be synthesized through straightforward chemical reactions that might include condensation or amide formation techniques, providing a practical pathway in laboratory settings.
  • Research Applications: Studies have shown that compounds with similar structures can exhibit a range of biological activities, including antimicrobial and antitumor efficacy, making this compound a candidate for further studies in pharmacology.

As emphasized by researchers, "the unique combination of functional groups in N-methyl-4-oxo-4-(3-pyridyl)butanamide opens the door to endless possibilities in drug design and discovery." This highlights the importance of exploring such compounds thoroughly to fully understand their potential and application in science.

Given its structure and properties, N-methyl-4-oxo-4-(3-pyridyl)butanamide exemplifies the interplay of organic chemistry and medicinal applications, making it a noteworthy subject of study for both chemists and pharmacologists alike.

Synonyms
Oxoamide
713-05-3
N-methyl-4-oxo-4-pyridin-3-ylbutanamide
4-oxo-4-(3-pyridyl)-N-methylbutanamide
gamma-(3-pyridyl)-gamma-oxo-N-methylbutyramide
OL86R2ULD8
4-(3-pyridyl)-4-oxo-N-methylbutyramide
N-methyl-4-oxo-4-(pyridin-3-yl)butanamide
N-METHYL-G-OXO-3-PYRIDINEBUTANAMIDE
UNII-OL86R2ULD8
SCHEMBL1954553
CHEMBL3544600
DTXSID80862385
CHEBI:166504
AKOS006293668
BA-2702
3-Pyridinebutanamide, N-methyl-gamma-oxo-
N-Methyl- gamma -oxo-3-pyridinebutanamide
NS00014893
.GAMMA.-(3-PYRIDYL)-.GAMMA.-OXO-N-METHYLBUTYRAMIDE