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Methylene Blue

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Identification
Molecular formula
C16H18N3SCl
CAS number
61-73-4
IUPAC name
N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine
State
State

At room temperature, this compound is typically in a solid state. It exists as a crystalline powder and is highly soluble in water, which adds to its practicality in various applications in laboratories and industrial settings.

Melting point (Celsius)
100.00
Melting point (Kelvin)
373.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
319.85g/mol
Molar mass
319.8530g/mol
Density
1.2000g/cm3
Appearence

N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine typically appears as a crystalline powder with a bluish tint. It is often vibrant and can exhibit different shades of blue depending on purity and concentration.

Comment on solubility

Solubility of N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine: C16H18N3SCl

The solubility of N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine can be quite complex due to its intricate structure. Here are some key points to consider:

  • Polarity: The presence of the amine group (–NH2) can enhance solubility in polar solvents, while the hydrophobic tricyclic structure may impede solubility in water.
  • Solvent Type: This compound is likely more soluble in organic solvents such as ethanol or methanol compared to aqueous solutions, due to the balance of hydrophilic (–NH2) and hydrophobic characteristics.
  • pH Influence: The solubility could also be influenced by pH, with amine groups potentially becoming protonated in acidic conditions, increasing their solubility in water.
  • Concentration Effects: At higher concentrations, solubility behavior might change, leading to possible precipitation or saturation effects.

Overall, the solubility behavior of this compound is a fascinating interplay between its unique chemical structure and the properties of the solvent system used. Understanding these characteristics is crucial for applications in fields like pharmacology and materials science.

Interesting facts

N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine

N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine is a fascinating compound that showcases the complexity of organic chemistry through its intricate molecular structure. This compound features a unique combination of a tricyclic framework and a blend of aliphatic and aromatic components, leading to a diverse range of potential applications. Here are some interesting facts about this intriguing chemical:

  • Structural Complexity: The presence of the tricyclo framework offers not only aesthetic appeal but also enhances the compound's reactivity and interaction with various biological systems.
  • Potential Applications: Given its structure, this compound could play a role in medicinal chemistry, potentially serving as a lead compound in the development of new pharmaceuticals targeting specific biological pathways.
  • Unique Reactivity: The presence of both the amine and imine functionalities in its structure allows for versatile chemical reactions, enabling it to participate in a wide range of synthetic pathways and modifications.
  • Biological Interest: Compounds like this often attract attention for their potential as bioactive agents, influencing enzymatic activities or exhibiting unique pharmacological properties.

In conclusion, N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine stands as a testament to the beauty and intricacy of molecular design in chemistry. As researchers explore this compound further, we may uncover its hidden properties and applications that could change how we approach certain chemical challenges.

Synonyms
nortriptyline
72-69-5
Aventyl
Desitriptilina
Noramitriptyline
Lumbeck
Avantyl
Desmethylamitriptyline
Noritren
Sensaval
Ateben
Demethylamitriptyline
Sesaval
Nortryptiline
Nortryptyline
Demethylamitryptyline
Pamelor
Nortriptilina
Nortriptylinum
Nortrilen
Amitryptyline, demethyl-
Psychostyl
Nortriptylinum [INN-Latin]
nortriptylina
CCRIS 9175
UNII-BL03SY4LXB
BL03SY4LXB
1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methyl-
EINECS 200-788-8
NSC-757234
BRN 2216786
CHEBI:7640
Aventyl;Desitriptilina
Nortriptyline (INN)
HSDB 3371
5-(3-Methylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene
3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine
Pamelor hydrochloride
5-(3-(Methylamino)propylidene)dibenzo(a,e)cyclohepta(1,5)diene
NCI-169453
5-(alpha-Methylaminopropylidene)dibenzo(a,d)cyclohepta(1,4)diene
N-Methyl-3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yliden)propylamin
10,11-Dihydro-5-(3-methylaminopropylidene)-5H-dibenzo(a,d)(1,4)cycloheptene
10,11-Dihydro-N-methyl-5H-dibenzo(a,d)cycloheptene-delta(5,gamma)-propylamine
3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methylpropylamine
3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine
N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine
Desitriptyline
DTXSID9023384
Nortriptylene hydrochloride
1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-
5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N-methyl-
NSC 757234
Desmethylamitriptylin
Nortriptilina [DCIT]
NSC169453
NORTRIPTYLINE [INN]
Nortriptylinum (INN-Latin)
Nortriptyline [INN:BAN]
Demethylamitriptylene
10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Delta(5,gamma)-propylamine
3-(10,11-DIHYDRO-5H-DIBENZO(A,D)(7)ANNULEN-5-YLIDENE)-N-METHYLPROPAN-1-AMINE
Nortrilen (TN)
NSC78248
CAS-894-71-3
Lambeck
5-[3-(Methylamino)propylidene]dibenzo[a,E]cyclohepta[1,5]diene
Triptyline-M nor
10,11-Dihydro-5-(3-methylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptene
10,11-dihydro-N-methyl-5H-dibenzo(a,d)cycloheptene-delta5,gamma-propylamine
10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Delta5,gamma-propylamine
3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methyl-1-propanamine
3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methylpropylamine
Demethylamitryptylene
NCI169453
Spectrum_001041
Psychostyl (Salt/Mix)
Prestwick0_000254
Prestwick1_000254
Prestwick2_000254
Prestwick3_000254
Spectrum2_000997
Spectrum3_000526
Spectrum4_000455
Spectrum5_001377
Lopac-N-7261
NORTRIPTYLINE [MI]
CHEMBL445
Nortiptylinum (INN-Latin)
NCIStruc1_000856
NCIStruc2_000700
NCIOpen2_004361
BIDD:PXR0187
Lopac0_000868
SCHEMBL34527
BSPBio_000068
BSPBio_002111
KBioGR_000870
KBioSS_001521
NORTRIPTYLINE [VANDF]
DivK1c_000151
SPECTRUM1500442
SPBio_001093
SPBio_002287
NORTRIPTYLINE [WHO-DD]
BPBio1_000076
DTXCID903384
GTPL2404
HMS500H13
KBio1_000151
KBio2_001521
KBio2_004089
KBio2_006657
KBio3_001611
N06AA10
NINDS_000151
3-(10,11-Dihydro-5H-dibenzo
BDBM112777
HMS1920B20
HMS2091J20
KUC112478N
Pharmakon1600-01500442
CCG-38266
NCGC00014483
NSC757234
PDSP1_001805
PDSP2_001788
DB00540
FN28876
SDCCGSBI-0050843.P006
(2)10,11-Dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-.delta.5.gamma.-propylamine
IDI1_000151
MRF-0000480
QTL1_000063
NCGC00014483-02
NCGC00014483-03
NCGC00014483-04
NCGC00014483-05
NCGC00014483-06
NCGC00014483-07
NCGC00014483-08
NCGC00014483-09
NCGC00014483-10
NCGC00014483-11
NCGC00014483-12
NCGC00014483-14
NCGC00014483-16
NCGC00014483-23
NCGC00024261-03
NCGC00024261-04
NCGC00024261-05
NCGC00024261-06
DA-56264
KSC-315-028-
methyl({3-[(2E)-tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]propyl})amine
MS-23718
NCI60_001354
SBI-0050843.P004
US8629135, SW-02
DB-240489
HY-118620
AB00052061
CS-0067638
NS00010393
EN300-57709
C07274
D08288
F82279
Q61387
AB00052061_16
SR-01000000223-4
BRD-K91263825-003-03-2
BRD-K91263825-003-21-4
AMITRIPTYLINE HYDROCHLORIDE IMPURITY C [EP IMPURITY]
10,11-Dihydro-N-methyl-5H-dibenzo(a,d)cycloheptane-.DELTA.,.gamma.-propylamine
10,11-DIHYDRO-N-METHYL-5H-DIBENZO(A,D)CYCLOHEPTENE-D(SUP5,.GAMMA.)-PROPYLAMINE
10,11-DIHYDRO-N-METHYL-5H-DIBENZO(A,D)CYCLOHEPTENE-D(SUP5,gamma)-PROPYLAMINE
3-(10,11-Dihydro-5H-dibenzo[a,d] cyclohepten-5-ylidene)-N-methyl-1-propanamine
3-(10,11-Dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N-methyl-1-propanamine
3-(5,6-dihydrodibenzo[[?],[?]][7]annulen-11-ylidene)-N-methyl-propan-1-amine
5H-Dibenzo(a,d)cycloheptene-delta(5,gamma)-propylamine, 10,11-dihydro-N-methyl
5H-Dibenzo[a,d]cycloheptene-.DELTA.5,.gamma.-propylamine, 10,11-dihydro-N-methyl-
200-788-8
21B
methyl({3-[(2E)-tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene]propyl})amine
methyl(3-{tricyclo[9.4.0.0,3,8]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene}propyl)amine