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Lidocaine N-oxide

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Identification
Molecular formula
C14H23N3O2
CAS number
51942-52-6
IUPAC name
N-[ethyl-[2-(ethylamino)ethyl]amino]-N-oxido-nitrous amide
State
State

At room temperature, Lidocaine N-oxide is a solid compound. It is stable under normal conditions of use and storage.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
273.00
Boiling point (Kelvin)
546.15
General information
Molecular weight
250.34g/mol
Molar mass
250.3360g/mol
Density
1.0600g/cm3
Appearence

Lidocaine N-oxide appears as a white crystalline powder. It is odorless and forms crystals that may vary slightly in shape depending on the method of crystallization.

Comment on solubility

Solubility of N-[ethyl-[2-(ethylamino)ethyl]amino]-N-oxido-nitrous amide

The solubility of the compound N-[ethyl-[2-(ethylamino)ethyl]amino]-N-oxido-nitrous amide, with the chemical formula C14H23N3O2, is influenced by several factors, primarily its molecular structure and the presence of functional groups. Here are some key points regarding its solubility:

  • Polarity: The presence of functional groups such as amines and the nitroso group contributes to the molecular polarity, which typically enhances solubility in polar solvents.
  • Hydrogen Bonding: The ability of the compound to participate in hydrogen bonding can significantly increase its solubility in water and other polar solvents.
  • Hydrophobic Regions: The ethyl groups present in the chain may create hydrophobic regions, potentially reducing the overall solubility in highly polar solvents.
  • Solvent Compatibility: Solubility is also affected by the solvent used; it may exhibit better solubility in organic solvents such as ethanol or methanol compared to non-polar solvents.
  • Concentration: Increasing temperature and stirring could help to increase solubility, particularly in cases where solid solubility is limited.

Ultimately, the solubility of this compound is a balancing act between its polarity and hydrophobic characteristics, making it soluble under certain conditions while remaining less soluble in others. Understanding these nuances is crucial for practical applications in various chemical environments.

Interesting facts

Interesting Facts about N-[ethyl-[2-(ethylamino)ethyl]amino]-N-oxido-nitrous amide

N-[ethyl-[2-(ethylamino)ethyl]amino]-N-oxido-nitrous amide is a fascinating compound that showcases the complex interplay of organic chemistry and medicinal applications. Below are some key insights about this intriguing compound:

  • Bioactivity: This compound is notable for its potential bioactive functions, which may provide insights in the field of drug design and development.
  • Unique Functional Groups: The presence of nitrous oxide and amino functionalities within its structure allows for diverse reactivity and interaction with biological systems, making it a subject of study for medicinal chemists.
  • Structure-Activity Relationships: Understanding the structure of this compound can aid researchers in modifying its attributes, potentially enhancing efficacy and reducing toxicity in therapeutic contexts.
  • Applications in Research: Compounds like this one are instrumental in pharmacological research, particularly in investigating novel mechanisms of action for treating various diseases.

This compound undoubtedly represents the rich tapestry of organic molecules being explored in modern chemistry and pharmacology. As noted by chemists, "the more complex the compound, the greater the potential for discovery." With its layered structure and unique properties, N-[ethyl-[2-(ethylamino)ethyl]amino]-N-oxido-nitrous amide is a prime example of how chemical innovation can lead to advancements in science and medicine.


In conclusion, the study of such compounds not only enhances our understanding of chemical interactions but also fuels the quest for new therapeutic agents in the ongoing battle against diseases.