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Butylphenylacetamide

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Identification
Molecular formula
C12H17NO
CAS number
4195-81-7
IUPAC name
N-butyl-N-phenyl-acetamide
State
State

At room temperature, butylphenylacetamide is in a liquid state, which is typical for many organic compounds of similar structure and size.

Melting point (Celsius)
12.00
Melting point (Kelvin)
285.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
191.27g/mol
Molar mass
191.2740g/mol
Density
1.0100g/cm3
Appearence

Butylphenylacetamide appears as a colorless to pale yellow liquid. It is generally clear and displays low viscosity, making it easy to handle in liquid form.

Comment on solubility

Solubility of N-butyl-N-phenyl-acetamide

N-butyl-N-phenyl-acetamide, with the chemical formula C13H17NO, exhibits interesting solubility characteristics that merit discussion.

General Solubility Characteristics:

This compound is primarily regarded as being:

  • Moderately soluble in organic solvents such as ether and chloroform.
  • Poorly soluble in water due to its relatively large hydrophobic butyl and phenyl groups, which decrease the overall polarity of the molecule.

Factors Influencing Solubility:

Several factors affect the solubility of N-butyl-N-phenyl-acetamide:

  • Hydrophobic interactions: The butyl and phenyl groups' size contributes to its hydrophobic nature, resulting in limited interactions with polar solvents like water.
  • Temperature: Solubility can increase with temperature, facilitating dissolution in organic solvents.
  • Presence of Functional Groups: The amide group (-C(O)NH-) can participate in hydrogen bonding, enhancing solubility in polar solvents to a minor extent.

Ultimately, the solubility of N-butyl-N-phenyl-acetamide reflects an intriguing balance between its hydrophobic and polar characteristics. To summarize, while this compound is well suited for non-polar environments, it presents notable challenges when attempting to dissolve it in aqueous solutions.

Interesting facts

Intriguing Aspects of N-butyl-N-phenyl-acetamide

N-butyl-N-phenyl-acetamide is a fascinating compound with a variety of applications and properties that make it significant in the field of chemistry. Here are some interesting facts to consider:

  • Versatile Applications: This compound is often utilized in organic synthesis and serves as an important intermediate in the preparation of various pharmaceuticals and agrochemicals.
  • Amide Functionality: The presence of the amide group in its structure contributes to its chemical reactivity and is crucial for interacting with biological systems, enhancing its potential as a drug candidate.
  • Solubility: N-butyl-N-phenyl-acetamide exhibits unique solubility characteristics, which can be influenced by the length of the butyl group, making it a subject of study in solubility and partitioning phenomena.
  • Thermodynamic Properties: The thermodynamic behavior of this compound can provide insights into molecular interactions and stability, making it a valuable substance for researchers investigating molecular dynamics.
  • Structural Significance: Understanding the stereochemistry and functional groups of N-butyl-N-phenyl-acetamide can lead to advancements in the synthesis of more complex organic compounds.

As a chemistry student or a scientist, it is essential to appreciate the broader implications of such compounds in real-world applications, ranging from medicinal chemistry to material science. Its intriguing molecular structure opens up numerous avenues for research and innovation.

In conclusion, N-butyl-N-phenyl-acetamide is not merely a compound; it's a gateway to understanding complex chemical interactions and the synthesis of essential materials for future advancements.

Synonyms
N-BUTYLACETANILIDE
N-Butyl-N-phenylacetamide
91-49-6
Butylacetanilide
Acetanilide, N-butyl-
Acetamide, N-butyl-N-phenyl-
N-butyl acetylaniline
Caswell No. 124
Acetic acid, amide, N-butyl-N-phenyl-
HSDB 2696
N-butyl-N-phenyl-acetamide
NSC 7662
EINECS 202-071-5
UNII-8M351V3SUN
EPA Pesticide Chemical Code 000401
BRN 2804963
8M351V3SUN
AI3-02484
NSC-7662
BUTYLACETANILIDE [HSDB]
DTXSID2042197
n-n-butylacetanilide
N-butylacetanilid
Acetanilide, Nbutyl
NButylNphenylacetamide
Acetamide, NbutylNphenyl
N-butyl-N-phenylethanamide
SCHEMBL817611
WLN: 4NR&V1
DTXCID0022197
NSC7662
Acetic acid, amide, NbutylNphenyl
AKOS006241926
AC-19529
CS-0368125
NS00039398
ACETIC ACID, AMIDE, N-BUTYL-N-PHENYL
Q15632770
202-071-5