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Thiabenazepam

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Identification
Molecular formula
C15H18ClN3O1
CAS number
29297-49-6
IUPAC name
N'-[(5-chloro-2-thienyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine
State
State

Thiabenazepam is typically found in a solid crystalline form at room temperature.

Melting point (Celsius)
123.15
Melting point (Kelvin)
396.30
Boiling point (Celsius)
423.15
Boiling point (Kelvin)
696.30
General information
Molecular weight
373.88g/mol
Molar mass
373.8820g/mol
Density
1.2700g/cm3
Appearence

Thiabenazepam appears as a crystalline solid. It is generally white to off-white in color.

Comment on solubility

Solubility of N'-[(5-chloro-2-thienyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine

The solubility of N'-[(5-chloro-2-thienyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine can be influenced by various factors due to its complex structure. Overall, understanding solubility is crucial for determining its practical applications in chemical processes and formulations.

Factors Affecting Solubility

  • Polarity: The presence of both thienyl and pyridyl groups suggests a degree of polarity in the molecule, which may enhance solubility in polar solvents.
  • Hydrogen Bonding: The amine functional groups can participate in hydrogen bonding, potentially increasing solubility in water and other polar solvents.
  • Temperature: Like many organic compounds, solubility can change with temperature. Typically, increased temperatures lead to enhanced solubility.
  • pH of the Solution: As a weak base, the solubility may vary significantly with changes in pH, with more pronounced effects in acidic or basic conditions.

“The solubility balance often dictates the pathways for chemical reactions and biological activity.”

This compound is expected to be soluble to some extent in organic solvents such as methanol or ethanol, while its exact solubility will depend on concentration and conditions. Further studies and experimentation would be essential to pinpoint actual solubility values, enabling better utilization in research and industrial applications.

Interesting facts

Interesting Facts about N'-[(5-chloro-2-thienyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine

This compound, known for its complex structure and functionality, is a fascinating example of synthetic organic chemistry. Its incorporation of diverse structural elements leads to a variety of chemical behaviors, making it a subject of interest in multiple fields such as medicinal chemistry and material science.

Structural Features

  • Thienyl moiety: The presence of the thienyl group, which is derived from thiophene, contributes to the compound's electronic properties. Thiophene derivatives are often used in organic electronics due to their ability to conduct electricity.
  • Pyridine ring: The pyridyl component enhances the compound's chelating abilities, often resulting in interesting interactions with metal ions, useful in various catalytic processes.
  • Chloro substituent: The chlorinated nature of this compound can provide additional sites for reactivity, potentially leading to more complex couplings in synthetic pathways.

Applications

Given its unique structural characteristics, this compound has potential applications in:

  • Pharmaceutical development: Compounds like this may have bioactive properties, making them candidates for research in drug discovery.
  • Material innovations: As highlighted earlier, its conductive properties may be harnessed in the creation of new materials, especially in electronic applications.
  • Catalysis: Its ability to form stable complexes with metal ions opens avenues for research into catalysis in organic reactions.

As you delve deeper into the world of chemical compounds, this compound exemplifies how nuanced variations in structure can lead to vastly different functionalities and applications. It encourages scientists to explore the intricate dance of atoms and functional groups, ultimately advancing our understanding of chemistry and its implications in real-world scenarios.

Synonyms
Chloropyrilene
CHLOROTHEN
Histachlorylene
Pyrithen
Chloromethapyrilene
Chlorthenylpyramine
Tagathen
148-65-2
Chlorothenylpyramine
Chlorpyrilenum
Chloropyrilenum
Cloropirilenio
Chloropyrilene [INN:BAN]
NCI-C60559
Chloropyrilenum [INN-Latin]
Cloropirilenio [INN-Spanish]
Cloropirileno
CCRIS 4768
HSDB 5183
BRN 0261143
CHLOROTHEN [MI]
2-((5-Chloro-2-thenyl)(2-dimethylaminoethyl)amino)pyridine
Y6068K376I
2-Thenylamine, 5-chloro-N-(2-(dimethylamino)ethyl)-N-2-pyridyl-
CHLOROPYRILENE [INN]
Ethylenediamine, N-(5-chloro-2-thenyl)-N',N'-dimethyl-N-2-pyridyl-
N,N-Dimethyl-N'-(2-pyridyl)-N'-(5-chloro-2-thenyl)ethylenediamine
CHLOROPYRILENE [HSDB]
N'-[(5-chlorothiophen-2-yl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine
CHLOROPYRILENE [WHO-DD]
DTXSID5074848
Pyridine, 2-((5-chloro-2-thenyl)(2-(dimethylamino)ethyl)amino)-
4-22-00-03951 (Beilstein Handbook Reference)
1,2-Ethanediamine, N-((5-chloro-2-thienyl)methyl)-N',N'-dimethyl-N-2-pyridinyl-
Chlorothen; Chlorthenylpyramine; Histachlorylene
1,2-Ethanediamine, N-[(5-chloro-2-thienyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-
Chloropyrilenum (INN-Latin)
Cloropirilenio (INN-Spanish)
Pyridine, 2-[(5-chloro-2-thenyl)[2-(dimethylamino)ethyl]amino]-
2-((5-Chloro-2-thenyl)(2-(dimethylamino)ethyl)amino)pyridine
cloropirilene
Chloropyrilen
UNII-Y6068K376I
SCHEMBL29707
CHEMBL2110628
DTXCID9034810
CHEBI:135246
XAEXSWVTEJHRMH-UHFFFAOYSA-N
NS00002322
Q5103211
2-((5-CHLORO-2-THENYL)(2-DIMETHYLAMINO)ETHYL)AMINO)PYRIDINE
5-CHLORO-N-(2-(DIMETHYLAMINO)ETHYL)-N-2-PYRIDYL-2-THENYLAMINE
N,N-DIMETHYL-N'-2-PYRIDYL-N-(5-CHLORO-2-THENYL)-N'-ETHYLENEDIAMINE
N,N-DIMETHYL-N'-(ALPHA-PYRIDYL)-N'-(2-METHYL-5-CHLOROTHIENYL)ETHYLENEDIAMINE
N-((5-CHLORO-2-THIENYL)METHYL)-N',N'-DIMETHYL-N-2-PYRIDINYL-1,2-ETHANEDIAMINE
N-5-CHLORO-2-THIENYLMETHYL-N',N'-DIMETHYL-N-2-PYRIDYLETHYLENEDIAMINE