Interesting facts
Interesting Facts about N-(4-sulfamoylphenyl)acetamide
N-(4-sulfamoylphenyl)acetamide, often recognized for its significant role in medicinal chemistry, is an organic compound that has garnered attention for its intriguing properties and applications. Here are some interesting highlights about this compound:
- Medical Relevance: This compound is closely related to sulfonamide antibiotics, which were among the first synthetic antimicrobial agents. The incorporation of a sulfamoyl group contributes to its potential therapeutic properties.
- Mechanism of Action: It is known that sulfonamides, including derivatives like N-(4-sulfamoylphenyl)acetamide, work by inhibiting the bacterial enzyme dihydropteroate synthase, which is crucial for folate synthesis in bacteria. This makes it effective in combating bacterial infections.
- Structure-Activity Relationship: The specific arrangement of the sulfonamide group and the phenyl ring in its structure is fundamental in determining its activity against various pathogens. Changes in these functional groups can lead to significant alteration in effectiveness.
- Biochemical Studies: Research has shown that compounds similar to N-(4-sulfamoylphenyl)acetamide are pivotal in studying metabolic pathways, particularly in understanding bacterial resistance mechanisms and developing new antibacterial treatments.
- Drug Development: With continuing research into its properties, this compound may inspire novel drug candidates, particularly for conditions caused by resistant strains of bacteria.
- Toxicology Considerations: While exploring its benefits, scientists also examine the potential toxicity and side effects associated with sulfamoyl compounds, which enhances the understanding of safe therapeutic use.
As a chemistry student, understanding N-(4-sulfamoylphenyl)acetamide means delving into the rich interplay of structure, activity, and medicinal application. The need for innovative solutions in antibiotic drug discovery makes this compound a compelling subject of study in both academic and pharmaceutical research settings.
Synonyms
4-Acetamidobenzenesulfonamide
121-61-9
N-(4-Sulfamoylphenyl)acetamide
Acetylsulfanilamide
N4-ACETYLSULFANILAMIDE
Neotherapol
p-Sulfamylacetanilide
Erytrin
4'-Sulfamylacetanilide
N4-Acetsulfanilamide
4-Acetylaminobenzenesulfonamide
4'-Sulfamoylacetanilide
Sulfanilamide-N4-acetate
N'-Acetylsulphanilamide
4'-Sulphamoylacetanilide
p-Sulfamoylacetanilide
p-(Acetylamino)benzenesulfonamide
p-Acetamidobenzenesulfonamide
Acetanilide, 4'-sulfamoyl-
Benzenesulfonamide, 4-(acetylamino)-
Benzenesulfonamide, p-acetamido-
N-(4-Sulphamoylphenyl)acetamide
N-4-Acetylsulfanilamide
NSC 217
N(sup 4)-Acetsulfanilamide
N(sup 4)-Acetylsulfanilamide
N-(4-(Aminosulfonyl)phenyl)acetamide
N-(4-Sulfamylphenyl)acetamide
CCRIS 6813
Sulfanilamide-N(sup 4)-acetate
Acetamide, N-[4-(aminosulfonyl)phenyl]-
A-319
EINECS 204-486-7
BRN 0746675
N-[4-(AMinosulf
Acetamide, N-(4-(aminosulfonyl)phenyl)-
DTXSID4041529
AI3-08023
NSC-217
MFCD00035784
CHEMBL687
340484WZ3L
NSC-406839
N4-ACETYL METABOLITE
ACETYLSULFANILAMIDE, N4-
DTXCID2021529
PKOFBDHYTMYVGJ-UHFFFAOYSA-
N4-ACETYLSULFANILAMIDE [MI]
N-[4-(Aminosulfonyl)phenyl]acetamide
SULFACETAMIDE SODIUM IMPURITY B [EP IMPURITY]
SULFACETAMIDE SODIUM IMPURITY B (EP IMPURITY)
Acetsulfanilamide
UNII-340484WZ3L
N-(4-Sulfamoyl-phenyl)-acetamide
N4 -acetylsulfanilamide
Enamine_001217
Cambridge id 5152132
Oprea1_094374
Oprea1_582774
4-Acetamido-benzenesulfonamide
SCHEMBL359721
aromatic sulfonamide compound 8
NSC217
4-N-Acetylaminophenylsulfonamide
BDBM16643
aniline, N'-acetyl-4-sulphamoyl-
HMS1397H07
AAA12161
Tox21_300850
NSC406839
STL308440
AKOS000141336
acetamide, N-(4-aminosulfonylphenyl)-
HY-W069721
PS-4449
SDCCGMLS-0064665.P001
N-[4-(Aminosulfonyl)phenyl]acetamide #
NCGC00248191-01
NCGC00254753-01
CAS-121-61-9
SY081511
DB-061940
A0115
CS-0080221
NS00011892
EN300-15532
Acetamide, N-(4-(aminosulfonyl)phenyl)-(9CI)
Q27256303
Z27682721
Solubility of N-(4-sulfamoylphenyl)acetamide
N-(4-sulfamoylphenyl)acetamide, a compound that falls under the category of sulfonamide derivatives, has unique solubility characteristics that can impact its practical applications. Generally, the solubility of this compound can be influenced by several factors:
In summary, while N-(4-sulfamoylphenyl)acetamide is expected to be soluble, the degree of solubility will depend on the specific conditions and the solvent utilized. Continued exploration into these aspects can provide further insights into its behavior in various environments.