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Pyrilamine

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Identification
Molecular formula
C17H23N3O
CAS number
91-84-9
IUPAC name
N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine
State
State

At room temperature, pyrilamine is typically in a solid state.

Melting point (Celsius)
67.00
Melting point (Kelvin)
340.15
Boiling point (Celsius)
307.70
Boiling point (Kelvin)
580.85
General information
Molecular weight
285.39g/mol
Molar mass
285.3890g/mol
Density
1.0199g/cm3
Appearence

Pyrilamine, also known as Mepyramine, typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine

The solubility of the compound N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine (C17H23N3O) can be influenced by several factors related to its molecular structure:

  • Polarity: The presence of amine groups and the methoxy group contributes to the overall polarity of the molecule, which may enhance its solubility in polar solvents.
  • Hydrogen Bonding: The ability of the amine groups to form hydrogen bonds can further increase solubility in polar solvents, particularly in aqueous solutions.
  • Hydrophobic Interactions: The aromatic ring (4-methoxyphenyl) introduces hydrophobic characteristics that can impact solubility in non-polar solvents.
  • Temperature and pH: These factors can greatly affect solubility; higher temperatures generally increase solubility, whereas varying pH can alter the ionization state of the amine groups, thereby affecting solubility.

In summary, while the solubility of this compound can be significant in certain solvents due to its polar functional groups, it may present challenges in non-polar environments. Therefore, understanding the solubility profile is essential for any practical applications or further studies of this compound. As a specific example, it is often soluble in ethanol and other polar organic solvents but may have limited solubility in hexane or other non-polar solvents.

Interesting facts

Interesting Facts about N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine

N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine, often referred to in research as a multifunctional compound, has sparked considerable interest in various scientific fields.

Chemical Characteristics

  • Amine Functions: This compound features two amine groups which contribute to its reactivity and can participate in various nucleophilic reactions.
  • Pyridyl Influence: The presence of the pyridine ring is significant because it can enhance the compound's ability to bind to metal ions, making it valuable in coordination chemistry.
  • 4-Methoxyphenyl Group: The methoxy group enhances solubility and can also influence the compound's interaction with biological targets, potentially impacting its pharmacological properties.

Applications

  • Pharmaceutical Development: Researchers are exploring its potential as a drug candidate, particularly for neurological conditions due to its ability to penetrate biological membranes.
  • Material Sciences: This compound might be utilized in the development of novel materials, especially those requiring tailored electronic properties.
  • Analytical Chemistry: It has implications in the fields of analytical chemistry, where it can serve as a ligand in various assays and detection methods.

Scientific Insights

The synthetic route to producing this compound often involves advanced chemical techniques, allowing for the close examination of structure-activity relationships. Notably, *“The diversity of functional groups within the molecule creates numerous pathways for chemical transformation,”* making it a highly versatile compound for further research.

Intriguingly, the interactions of this compound with biological systems highlight the importance of *molecular design* in developing compounds that could influence therapeutic avenues. Researchers continue to investigate its mechanisms of action and potential effects on living organisms, opening up a fascinating narrative of innovation and discovery.

Synonyms
Mepyramine
pyrilamine
91-84-9
Pyranisamine
Anthisan
Dorantamin
Mepiramine
Anhistabs
Anhistol
Antalergan
Antallergan
Antamine
Copsamine
Harvamine
Histacap
Histalon
Histapyran
Histasan
Maranhist
Neoantergan
Paraminyl
Statomin
Thylogen
Coradon
Dipane
Isamin
Kriptin
Mepyren
Nyscaps
Parmal
Pyramal
Stamine
Stangen
Neo-Bridal
Afko-Hist
Mepyramin
PYRA
Mepiramina
Mepyraminum
Wait's green mountain antihistamine
RP 2786
NCI-C60651
Pyrilamide
CCRIS 4865
Neobridal
N',N'-Dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)ethylenediamine
Pyrlex
HSDB 5187
1,2-Ethanediamine, N-((4-methoxyphenyl)methyl)-N',N'-dimethyl-N-2-pyridinyl-
Mepyraminum [INN-Latin]
Mepiramina [INN-Spanish]
UNII-HPE317O9TL
EINECS 202-102-2
HPE317O9TL
NSC 13136
NSC-13136
BRN 0269019
CHEBI:6762
DTXSID9023542
NSC13136
2-((p-Methoxybenzyl)(2-(dimethylamino)ethyl)amino)pyridine
CHEMBL511
Pyridine, 2-((p-methoxybenzyl)(2-(dimethylamino)ethyl)amino)-
N-(p-Methoxybenzyl)-N',N'-dimethyl-N-2-pyridyl-1,2-ethanediamine
DTXCID303542
102206-59-7
2-((2-(Dimethylamino)ethyl)-(p-methoxybenzyl)amino)pyridine
N-(p-Methoxybenzyl)-N',N'-dimethyl-N-2-pyridylethylenediamine
Pyridine, 2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-
N-(para-Methoxybenzyl)-N',N'-dimethyl-N-2-pyridylethylenediamine
N-p-Methoxybenzyl-N',N'-dimethyl-N-alpha-pyridylethylenediamine
N-para-Methoxybenzyl-N',N'-dimethyl-N-alpha-pyridylethylenediamine
5-22-08-00381 (Beilstein Handbook Reference)
Mepyramine (INN)
N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine
N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine
[3H]mepyramine
1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-
N-((4-Methoxyphenyl)methyl)-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine
N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine
p-Methoxybenzyl-alpha-pyridyl-dimethyl-aethylendiamin
R.d. 2786
NCGC00015822-09
MEPYRAMINE [INN]
Mepyraminum (INN-Latin)
N-(p-Methoxybenzyl)-N',N'-dimethyl-N-(alpha-pyridyl)ethylenediamine
Mepiramina (INN-Spanish)
MEPYRAMINE (MART.)
MEPYRAMINE [MART.]
Mepyramin [German]
2-[(2-Dimethylaminoethyl)(p-methoxybenzyl)amino]pyridine
p-Methoxy-benzyl-.alpha.-pyridyl-dimethyl-aethylendiamin
2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine
Mepyramine [INN:BAN]
Pyridine, 2-[[2-(dimethylamino)ethyl](p-methoxybenzyl)amino]-
2-((2-(DIMETHYLAMINO)ETHYL)(P-METHOXYBENZYL)AMINO)PYRIDINE
N-(p-Methoxybenzyl)-N',N'-dimethyl-N-(.alpha.-pyridyl)ethylenediamine
N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine
CAS-91-84-9
[11C]pyrilamine
[11C]-pyrilamine
[11C]-Mepyramine
CAS-59-33-6
2-[(p-Methoxybenzyl)[2-(dimethylamino)ethyl]amino]pyridine
Pyriliamine
2-[[2-(Dimethylamino)ethyl]-(p-methoxybenzyl)amino]pyridine
Pyridine, 2-[(p-methoxybenzyl)[2-(dimethylamino)ethyl]amino]-
2-((2-DIMETHYLAMINOETHYL)(P-METHOXYBENZYL)AMINO)PYRIDINE
Pyrilamine salt with fine resin
3H]pyrilamine
N,N-dimethyl-N'-{[4-(methyloxy)phenyl]methyl}-N'-pyridin-2-ylethane-1,2-diamine
N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine
Histan (Salt/Mix)
Pymafed (Salt/Mix)
Antihist (Salt/Mix)
Minihist (Salt/Mix)
Spectrum_000904
Tocris-0660
Prefrin A (Salt/Mix)
PYRILAMINE [MI]
p-Methoxybenzyl-alpha-pyridyl-dimethyl-aethylendiamin [German]
Prestwick0_000289
Prestwick1_000289
Prestwick2_000289
Prestwick3_000289
Spectrum2_001306
Spectrum3_000605
Spectrum4_000493
Spectrum5_001264
Lopac-P-5514
MEPYRAMINE [HSDB]
PYRILAMINE [VANDF]
MEPYRAMINE [WHO-DD]
Lopac0_000890
Oprea1_317349
SCHEMBL19114
BSPBio_000198
BSPBio_002110
KBioGR_001005
KBioSS_001384
BIDD:GT0215
DivK1c_000175
SPBio_001371
SPBio_002417
BPBio1_000218
CCRIS 1330 (Salt/Mix)
GTPL1227
GTPL3957
BDBM22567
KBio1_000175
KBio2_001384
KBio2_003952
KBio2_006520
KBio3_001610
D04AA02
R06AC01
NINDS_000175
HMS2089M19
Tox21_110230
Tox21_200978
MFCD00023451
AKOS001637059
N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine
Tox21_110230_1
CCG-204972
DB06691
RD 2786
SDCCGSBI-0050865.P005
IDI1_000175
WLN: T6NJ BN2N1&1&1R DO1
WLN: T6NJ DN1R DO1&2N1&1
N-(p-Methoxybenzyl)-N',2-ethanediamine
NCGC00015822-01
NCGC00015822-02
NCGC00015822-03
NCGC00015822-04
NCGC00015822-05
NCGC00015822-06
NCGC00015822-07
NCGC00015822-08
NCGC00015822-10
NCGC00015822-11
NCGC00015822-12
NCGC00015822-13
NCGC00015822-15
NCGC00015822-17
NCGC00015822-21
NCGC00023513-02
NCGC00023513-04
NCGC00023513-05
NCGC00023513-06
NCGC00258531-01
TS-08382
SBI-0050865.P004
AB00053539
NS00008274
D08183
AB00053539-19
AB00053539_20
AB00053539_21
EN300-18535450
L000391
Q3800087
BRD-K97564742-050-04-6
BRD-K97564742-050-05-3
BRD-K97564742-050-31-9
BRD-K97564742-050-32-7
BRD-K97564742-051-02-8
BRD-K97564742-103-01-9
pyridine, 2-((2-dimethylaminoethyl)(p-methoxybenzyl)amino)-
pyridine, 2-[(2-dimethylaminoethyl) (p-methoxybenzyl) amino]-
1, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-
Ethylenediamine, N',N'-dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)-
Ethylenediamine,N'-dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)-
n,n-dimethyl-n'-(4-methoxybenzyl)-n'-(2-pyridyl)ethylenediamine
N,N-Dimethyl-N'-(p-methoxybenzyl)-N'-(2 -Pyridyl)ethylenediamine
N-(p-Methoxybenzyl)-N',N'-dimethyl-N-2-(pyridylethylene)diamine
N-p-Methoxybenzyl-N',N'-dimethyl-N-.alpha.-pyridylethylenediamine
Pyridine, 2-[[2-(dimethylamino)ethyl][p-methoxybenzyl)amino]]-
N,N-Dimethyl-N'-(4-methoxybenzyl)-N'-(.alpha.-pyridyl)-ethylenediaminene
N-(4-methoxybenzyl)-N ,N -dimethyl-N-pyridin-2-ylethane-1,2-diamine
N-Dimethylamino-aethyl-N-p-methoxy-benzyl-.alpha.-amino-pyridin-maleat
N-P-METHOXYBENZYL-N'N'-DIMETHYL-N-ALPHA-PYRIDYLETHYLENEDIAMINE
1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridyl-
N-((4-METHOXYPHENYL)METHYL)-N'N'-DIMETHYL-N-2-PYRIDINYL-1,2-ETHANEDIAMINE
N-((4-METHOXYPHENYL)METHYL)-N-2-PYRIDINYL-N',N'-DIMETHYL-1,2-ETHANEDIAMINE
1,2-Ethanediamine, N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-; 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl- (9CI); Pyridine, 2-[[2-(dimethylamino)ethyl](p-methoxybenzyl)amino]- (7CI,8CI); N1-[(4-Methoxyphen
202-102-2
Y5E