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Acetanisole

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Identification
Molecular formula
C9H10O2
CAS number
100-06-1
IUPAC name
N-(4-methoxyphenyl)acetamide
State
State

Acetanisole is in a liquid state at room temperature, due to its relatively low melting point.

Melting point (Celsius)
23.00
Melting point (Kelvin)
296.15
Boiling point (Celsius)
248.82
Boiling point (Kelvin)
521.97
General information
Molecular weight
151.17g/mol
Molar mass
151.1650g/mol
Density
1.1430g/cm3
Appearence

Acetanisole is typically a colorless to pale yellow liquid. It is known for its pleasant aromatic odor that resembles anise or licorice.

Comment on solubility

Solubility of N-(4-methoxyphenyl)acetamide (C9H10O2)

N-(4-methoxyphenyl)acetamide is a compound that exhibits interesting solubility characteristics. Understanding its solubility can provide insight into its behavior in various solvents and applications. Here are some key points regarding its solubility:

  • Common Solvents: N-(4-methoxyphenyl)acetamide is generally soluble in polar organic solvents such as ethanol and methanol.
  • Water Solubility: The compound shows limited solubility in water, which can be attributed to its molecular structure that includes a non-polar aromatic group.
  • Temperature Dependence: Solubility can increase with temperature, making heating a practical strategy for increasing its dissolution rate in solvents.
  • pH Factors: The solubility may also be affected by the pH of the solution, particularly due to the presence of the amide functional group which can engage in acid-base interactions.

In conclusion, while N-(4-methoxyphenyl)acetamide demonstrates good solubility in various polar solvents, its limited solubility in water emphasizes the importance of solvent choice in practical applications. As a general guideline, always consider both the solvent and environmental conditions when contemplating the dissolution of this compound.

Interesting facts

Exciting Facts about N-(4-methoxyphenyl)acetamide

N-(4-methoxyphenyl)acetamide, often referred to as a derivative of acetanilide, presents a captivating profile in the realm of organic chemistry. Here are some intriguing aspects to consider:

  • Structural Significance: The presence of the 4-methoxyphenyl group significantly influences the compound's reactivity and properties. This substitution can enhance biological activity, thus making it an important candidate in pharmaceutical research.
  • Versatile Applications: Due to its structure, N-(4-methoxyphenyl)acetamide may find a variety of applications in medicinal chemistry. It is often studied for its potential use as an analgesic or anti-inflammatory agent.
  • Intriguing Mechanisms: The interaction between the methoxy group and the aromatic ring plays a crucial role in how this compound interacts with enzymes and receptors, making it a subject of interest in drug design.
  • Synthetic Pathways: Chemists often explore different synthetic methods to produce this compound, including the use of acylation reactions that showcase its versatility and adaptability in laboratory settings.
  • Study of Substituent Effects: The compound serves as an excellent model for studying how different substituents impact the electronic properties of phenyl rings, an essential concept in organic chemistry.

As you dive into the properties and uses of N-(4-methoxyphenyl)acetamide, consider the implications of its unique structure. Understanding such compounds not only enhances our knowledge of organic chemistry but also opens doors for innovative drug discovery and design.

Synonyms
N-(4-Methoxyphenyl)acetamide
51-66-1
4'-Methoxyacetanilide
p-Acetanisidide
p-Acetanisidine
Methacetin
p-Methoxyacetanilide
4-METHOXYACETANILIDE
Acetamide, N-(4-methoxyphenyl)-
Aceto-p-anisidide
N-Acetyl-p-anisidine
Acetyl-p-anisidine
N-Acetyl-p-methoxyaniline
Acetanilide, 4'-methoxy-
4-(Acetylamino)anisole
NSC 4687
Aceto-p-anisidine
4-acetamidoanisole
EINECS 200-114-2
UNII-13E468TFHP
BRN 0387887
DTXSID6026325
N-(4-Methoxy-phenyl)-acetamide
AI3-00798
NSC-4687
ACETANISIDIDE, P-
MFCD00014963
N-(p-Methoxyphenyl)acetamide
P-ACETANISIDINE [MI]
13E468TFHP
DTXCID806325
CHEBI:139354
4-13-00-01092 (Beilstein Handbook Reference)
N-(4-Methoxyphenyl)acetic acid amide
p-Acetaniside
p-acetamidoanisole
4-acetaminoanisole
WLN: 1VMR DO1
N-(4-methoxyphenyl)ethanamide
SCHEMBL171415
N-(4-methoxyphenyl)-acetamide
CHEMBL3183230
SCHEMBL12015254
SCHEMBL17955676
NSC4687
HMS1783M19
Tox21_201131
STK045687
AKOS000121469
FM25132
CAS-51-66-1
NCGC00248932-01
NCGC00258683-01
DS-15877
SY078829
A0019
A7614
CS-0072050
NS00002763
EN300-15545
A15080
AE-641/00642037
SR-01000395318
SR-01000395318-1
Q27251512
Z28138902
F1962-0209
Methacetin; N-(4-Methoxyphenyl)acetamide; p-Acetanisidine
N-(4-Methoxyphenyl)acetamide;p-Acetanisidine;p-Methoxyacetanilide
T9V