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N-(4-hydroxyphenyl)octadecanamide

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Identification
Molecular formula
C24H39NO2
CAS number
58743-81-0
IUPAC name
N-(4-hydroxyphenyl)octadecanamide
State
State
At room temperature, N-(4-hydroxyphenyl)octadecanamide is in a solid state. Due to its long hydrocarbon chain characteristic of octadecanamides, it is a waxy solid that demonstrates low solubility in water. The compound is generally stable in ambient atmospheric conditions.
Melting point (Celsius)
92.00
Melting point (Kelvin)
365.15
Boiling point (Celsius)
533.20
Boiling point (Kelvin)
806.35
General information
Molecular weight
389.58g/mol
Molar mass
389.6400g/mol
Density
0.9210g/cm3
Appearence

N-(4-hydroxyphenyl)octadecanamide appears as a white to off-white crystalline solid. The compound is typically a powder that can clump together due to its relatively high fatty acid content. Due to its amide linkage, it demonstrates robust stability under ambient conditions.

Comment on solubility

Solubility of N-(4-hydroxyphenyl)octadecanamide

N-(4-hydroxyphenyl)octadecanamide, with its long hydrophobic octadecanamide chain and a polar hydroxyphenyl group, presents a unique solubility profile. Understanding its solubility characteristics is crucial for its applications in various fields, such as pharmaceuticals and materials science.

Key Points About Solubility:

  • Hydrophobic vs. Hydrophilic: The compound exhibits a balance between hydrophobicity due to its long carbon chain and hydrophilicity from the hydroxyl group.
  • Solvent Interaction: It is more likely to dissolve in non-polar solvents like hexane or chloroform, while solubility in polar solvents such as water is significantly limited.
  • Temperature Effect: Increased temperatures may enhance solubility in organic solvents, leading to better dissolution rates.
  • pH Influence: The solubility might also be affected by the pH of the solution, as charged or ionized forms can be more soluble.

In conclusion, the solubility behavior of N-(4-hydroxyphenyl)octadecanamide is a fascinating interplay between its hydrophobic and hydrophilic components. As one researcher noted, “The dual nature of such compounds often leads to unexpected behaviors in mixed solvent systems.” This complexity opens avenues for tailored applications in diverse chemical contexts.

Interesting facts

Interesting Facts about N-(4-hydroxyphenyl)octadecanamide

N-(4-hydroxyphenyl)octadecanamide, often referred to as octadecanamide with a hydroxyl group substituted at the para position of the phenyl ring, showcases a fascinating blend of chemical properties due to its unique structure. This compound falls under the category of amides, which are characterized by the presence of a carbonyl group linked to a nitrogen atom. Here are some notable features:

  • Biological Relevance: The compound holds significant interest in the field of biochemistry. Its structure facilitates interactions with biological membranes, making it a potential candidate for studies related to drug delivery systems and membrane dynamics.
  • Inhibition Studies: Research has indicated that compounds similar to N-(4-hydroxyphenyl)octadecanamide may exhibit inhibitory effects on certain enzymatic pathways. This points to its potential utility in therapeutic applications, particularly in areas such as cancer treatment.
  • Thermal Properties: Due to its long hydrocarbon chain, this compound may exhibit interesting thermal properties, which are valuable for applications that require thermal stability.
  • Cosmetic Applications: The hydroxyl group provides opportunities for incorporation into formulations, making it a candidate in the cosmetic industry for enhancing skin feel and moisture retention.

As a scientist or student exploring this compound, consider how its specific functional groups affect its interactions and applications. The presence of both hydrophobic (octadecane chain) and hydrophilic (hydroxyl group) functionalities gives rise to its amphiphilic characteristics, highlighting the significance of molecular design in creating compounds with desired properties.

In summary, N-(4-hydroxyphenyl)octadecanamide represents a bridge between chemistry and real-world applications, underscoring the importance of understanding molecular structures and their implications in various scientific fields.

Synonyms
N-(4-Hydroxyphenyl)stearamide
103-99-1
N-Stearoyl-p-aminophenol
Octadecanamide, N-(4-hydroxyphenyl)-
N-(4-hydroxyphenyl)octadecanamide
Suconox-18
Stearoyl-p-aminophenol
p-(Steroylamino)phenol
N-Stearoyl-4-aminophenol
Stearic acid-p-hydroxyanilide
Suconox 18, 4'-hydroxy-
N-4-Hydroxyphenylstearamide
NSC 166354
Octadecananilide, 4'-hydroxy-
EINECS 203-165-9
Octadecanamide,N-(4-hydroxyphenyl)-
Suconox 18
4-hydroxystearanilide
N-stearoyl p-amino phenol
Stearamide, m-hydroxyphenol
SCHEMBL39282
4'-HYDROXYSTEARANILIDE
BIDD:ER0270
DTXSID6059287
N-(4-Hydroxyphenyl) Stearamide
NSC166354
Octadecananilide, 4'-hydroxy-(8CI)
AKOS024319103
NSC-166354
NS00021463
G64718
203-165-9