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Triazolam

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Identification
Molecular formula
C17H12Cl2N4
CAS number
28911-01-5
IUPAC name
N-[(4-carbamimidoylcyclohexyl)methyl]-2-(2,2-diphenylethyl)-6-methyl-1,3-dioxo-5,8-dihydro-[1,2,4]triazolo[1,2-a]pyridazine-8-carboxamide
State
State

At room temperature, Triazolam is in a solid state.

Melting point (Celsius)
253.00
Melting point (Kelvin)
526.15
Boiling point (Celsius)
498.15
Boiling point (Kelvin)
771.30
General information
Molecular weight
343.22g/mol
Molar mass
343.7710g/mol
Density
1.3800g/cm3
Appearence

Triazolam appears as a white crystalline powder.

Comment on solubility

Solubility of N-[(4-carbamimidoylcyclohexyl)methyl]-2-(2,2-diphenylethyl)-6-methyl-1,3-dioxo-5,8-dihydro-[1,2,4]triazolo[1,2-a]pyridazine-8-carboxamide

The solubility of the compound N-[(4-carbamimidoylcyclohexyl)methyl]-2-(2,2-diphenylethyl)-6-methyl-1,3-dioxo-5,8-dihydro-[1,2,4]triazolo[1,2-a]pyridazine-8-carboxamide with the formula C17H12Cl2N4 presents interesting characteristics due to its unique molecular structure. Understanding its solubility is crucial for predicting its behavior in various environments.

  • Polarity: The presence of both hydrophobic (alkyl and aryl groups) and hydrophilic (carboxamide and chlorinated groups) components suggests the compound may exhibit moderate solubility in polar solvents.
  • Solvents: It is likely to be soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol, while displaying limited solubility in water due to its overall hydrophobic characteristics.
  • Common Trends: Many compounds with similar functional groups follow a pattern where increased molecular complexity leads to decreased solubility in aqueous environments.
  • Experimental Data: It’s essential to conduct experimental solubility tests to ascertain the precise solubility profile, as theoretical predictions may vary significantly.

In conclusion, various factors including temperature, pH, and the solvent system used will impact the solubility of this compound. Therefore, careful consideration of these elements is paramount when evaluating its practical applications.

Interesting facts

Interesting Facts about N-[(4-carbamimidoylcyclohexyl)methyl]-2-(2,2-diphenylethyl)-6-methyl-1,3-dioxo-5,8-dihydro-[1,2,4]triazolo[1,2-a]pyridazine-8-carboxamide

This compound, with its intricate structure, showcases the fascinating world of organic chemistry and medicinal chemistry. As a scientist or chemistry student, you'll find the following aspects particularly intriguing:

  • Complexity and Design: The structure contains multiple functional groups, which implies potential for diverse chemical reactivity. Its design exemplifies the structural diversity found in pharmaceutical compounds.
  • Triazole and Pyridazine Rings: This compound features both triazole and pyridazine moieties. These fused ring systems are important in many biological applications, such as acting as bioisosteres in drug design, where they can replace other functional groups to improve pharmacological properties.
  • Potential Biological Activity: Compounds with similar structures are often explored for therapeutic effects. Research indicates that triazole derivatives may exhibit antimicrobial, antifungal, or anticancer properties, offering a promising avenue for further investigation.
  • Diversified Applications: The diverse functionalities present in this molecule allow for potential applications beyond medicine, including agricultural chemistry and material science as catalysts or stabilizers.
  • Adapting to Chemical Innovations: The incorporation of unique substituents, such as the diphenylethyl group, provides an avenue for enhancing molecular interactions, which can be critical for achieving desired bioactivity and specificity in drug design.

In summary, this compound serves as a striking example of how organic chemistry intertwines with biology, showcasing not only the creativity of chemists but also the potential for discovering new solutions to health-related challenges. It encourages a deeper exploration into chemical synthesis, structure-activity relationships, and the ongoing quest for effective therapeutic agents.