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SCH-23390

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Identification
Molecular formula
C17H19ClN3O3S
CAS number
82652-98-6
IUPAC name
N-(4-azatricyclo[5.2.1.02,6]decan-4-yl)-4-chloro-3-sulfamoyl-benzamide
State
State

At room temperature, this compound is typically in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
277.00
Melting point (Kelvin)
550.00
Boiling point (Celsius)
465.30
Boiling point (Kelvin)
738.40
General information
Molecular weight
371.87g/mol
Molar mass
371.8400g/mol
Density
1.5210g/cm3
Appearence

The compound presents as a crystalline solid that can be white to off-white in appearance.

Comment on solubility

Solubility of N-(4-azatricyclo[5.2.1.02,6]decan-4-yl)-4-chloro-3-sulfamoyl-benzamide

The solubility of the compound N-(4-azatricyclo[5.2.1.02,6]decan-4-yl)-4-chloro-3-sulfamoyl-benzamide (C17H19ClN3O3S) can be intriguing due to its multifaceted structure. Understanding its solubility can help in various applications, particularly in pharmaceuticals. Here are key points regarding its solubility:

  • Water solubility: Compounds that contain sulfonamide groups often exhibit varying degrees of solubility in water, influenced by their overall polarity.
  • Organic solvents: This compound may find better solubility in organic solvents like ethanol or dimethyl sulfoxide (DMSO), which can help dissolve hydrophobic components.
  • pH dependence: The solubility might also be pH-dependent, where changes in the pH can affect the ionization of the sulfonamide group, potentially increasing its solubility in basic solutions.

Overall, the solubility profile of this compound suggests that careful consideration of solvent choices and environmental conditions is necessary for optimal dissolution. As the saying goes, "Like dissolves like," emphasizing the importance of matching solvent properties to the compound's characteristics for successful solubilization.

Interesting facts

Interesting Facts about N-(4-azatricyclo[5.2.1.02,6]decan-4-yl)-4-chloro-3-sulfamoyl-benzamide

This compound is a fascinating example of modern medicinal chemistry, reflecting the intricate relationship between structure and function in drug design. Here are some notable aspects:

  • Multi-functional Moiety: The presence of a chloro group, sulfamoyl group, and complex bicyclic structure highlights the compound's potential for interacting with biological targets, indicating its role in pharmacology.
  • Sulfamoyl Group: This group is often found in sulfonamide drugs, known for their antibacterial activity. It underscores the potential therapeutic applications that could stem from this compound.
  • Bicyclic Framework: The intricate bicyclic structure not only adds to the compound's stability but may also influence its ability to bind to specific targets in biological systems.
  • Drug Development: Understanding the structure-activity relationship (SAR) of this compound is crucial as it could lead to the development of new pharmaceuticals with improved efficacy and reduced side effects.
  • Cyclic Compounds: Cycles in organic compounds often result in unique properties, such as enhanced molecular rigidity, which can affect how the compound interacts in biological environments.

As one can see, N-(4-azatricyclo[5.2.1.02,6]decan-4-yl)-4-chloro-3-sulfamoyl-benzamide isn't just a complex chemical; it represents a blend of various chemical strategies that have significant implications in the fields of medicinal chemistry and drug development. Understanding and exploring such compounds can pave the way for revolutionary treatments in medicine.

As the renowned chemist, Linus Pauling, once said, "The best way to have a good idea is to have a lot of ideas." This compound may be a source of many innovative ideas in the pharmaceutical field.

Synonyms
tripamide
73803-48-2
ADR 033; E 614; Normonal; TDS; TDS (diuretic); Toripamide
CHEMBL4792274
DTXSID60860965
SB48779
4-chloro-N-(octahydro-2H-4,7-methanoisoindol-2-yl)-3-sulfamoylbenzamide
N-(4-Azatricyclo[5.2.1.02,6]decan-4-yl)-4-chloro-3-sulfamoylbenzamide